A novel experimental approach for the determination of aerodynamic coefficients for aeroelastic instability studies

2000 ◽  
Vol 84 (3) ◽  
pp. 289-305
Author(s):  
J.L.V. Brito ◽  
J.D. Riera
Keyword(s):  
Experimental Approach ◽  
Aerodynamic Coefficients ◽  
Aeroelastic Instability

Experimental Determination of the Effective Resolution Limit in Thick Specimens at High Voltages

1975 ◽  
Vol 33 ◽  
pp. 664-665
Author(s):  
Mircea Fotino
Keyword(s):  
Experimental Approach ◽  
Chromatic Aberration ◽  
Resolving Power ◽  
Biological Research ◽  
Specimen Thickness ◽  
Resolution Limit ◽  
High Voltage Electron Microscopy ◽  
Voltage Electron ◽  
Resolution Level

The use of thick specimens (0.5 μm to 5.0 μm or more) is one of the most resourceful applications of high-voltage electron microscopy in biological research. However, the energy loss experienced by the electron beam in the specimen results in chromatic aberration and thus in a deterioration of the effective resolving power. This sets a limit to the maximum usable specimen thickness when investigating structures requiring a certain resolution level.An experimental approach is here described in which the deterioration of the resolving power as a function of specimen thickness is determined. In a manner similar to the Rayleigh criterion in which two image points are considered resolved at the resolution limit when their profiles overlap such that the minimum of one coincides with the maximum of the other, the resolution attainable in thick sections can be measured by the distance from minimum to maximum (or, equivalently, from 10% to 90% maximum) of the broadened profile of a well-defined step-like object placed on the specimen.

Reynolds-averaged Navier–Stokes simulation of hydrofoil effects on hydrodynamic coefficients of a catamaran in forced oscillation

2016 ◽  
Vol 231 (2) ◽  
pp. 364-383
Author(s):  
Amin Najafi ◽  
Mohammad Saeed Seif
Keyword(s):  
High Speed ◽  
Experimental Approach ◽  
Navier Stokes ◽  
Hydrodynamic Coefficients ◽  
Laboratory Equipment ◽  
Factors Affecting ◽  
High Frequencies ◽  
Frequency Independent ◽  
Reynolds Averaged Navier Stokes

Determination of high-speed crafts’ hydrodynamic coefficients will help to analyze the dynamics of these kinds of vessels and the factors affecting their dynamic stabilities. Also, it can be useful and effective in controlling the vessel instabilities. The main purpose of this study is to determine the coefficients of longitudinal motions of a planing catamaran with and without a hydrofoil using Reynolds-averaged Navier–Stokes method to evaluate the foil effects on them. Determination of hydrodynamic coefficients by experimental approach is costly and requires meticulous laboratory equipment; therefore, utilizing the numerical methods and developing a virtual laboratory seem highly efficient. In this study, the numerical results for hydrodynamic coefficients of a high-speed craft are verified against Troesch’s experimental results. In the following, after determination of hydrodynamic coefficients of a planing catamaran with and without foil, the foil effects on its hydrodynamic coefficients are evaluated. The results indicate that most of the coefficients are frequency-independent especially at high frequencies.

scholarly journals EVALUATION OF THE VITALITY OF A FLANGED CONNECTION WITH A STEEL TOWER STRUCTURE WITH ACCOUNT OF EXPERIMENTAL DETERMINATION OF AERODYNAMIC COEFFICIENTS

2020 ◽  
Vol 82 (2) ◽  
pp. 215-224
Author(s):  
V.I. Erofeev ◽  
I.A. Samokhvalov
Keyword(s):  
Bearing Capacity ◽  
Numerical Study ◽  
Wind Load ◽  
Aerodynamic Coefficients ◽  
Metal Structures ◽  
Equivalent Stresses ◽  
Tower Structure ◽  
Calculation Results ◽  
Design Calculations

A numerical study of the survivability of the flange assembly is carried out upon reaching a critical load and in the presence of a defect in one of the design areas, taking into account the calculated values of the aerodynamic coefficients. An experiment is being carried out to determine the values of the wind load acting on the supporting legs of a metal tower. The calculation of the stressstrain state is performed using software system as SCAD Office and IDEA StatiCa 10.0. After calculating the forces in the core model of the structure, a threedimensional plate model of the assembly is formed and prepared for calculation. According to the results of the experiment, a graph was compiled with the values of aerodynamic coefficients, which were used in calculating the stressstrain state of the node. The analysis of the calculation results revealed that in the design (defectfree) state of the structure, the safety factor of the bearing units and elements is 35-40% (equivalent stresses were 165 MPa). If there is a defect in the metal structures of the belt in the region of the flange, the equivalent stresses increase to 247.6 MPa in the region of the cleavage (defective hole), thus, the margin in bearing capacity drops to 0.4%. As a result of the assessment of the survivability of the flange connection, it was revealed that the connection has a high potential survivability, in turn, the flange itself is able to work in the presence of some defects without reducing its bearing capacity to a critical level. The aerodynamic coefficients obtained in this work will determine the wind load on this type of profile and can be used in design calculations of tower structures for wind loads.

NMR for the design of functional mimetics of protein-protein interactions: one key is in the building of bridges

1998 ◽  
Vol 76 (2-3) ◽  
pp. 177-188 ◽  
Author(s):  
Jianxing Song ◽  
Feng Ni
Keyword(s):  
Protein Interactions ◽  
Binding Sites ◽  
Experimental Approach ◽  
Structural Information ◽  
Peptide Ligands ◽  
Protein Protein Interactions ◽  
Binding Residues ◽  
Related Proteins ◽  
Binding Inhibitors

Using the design of bivalent and bridge-binding inhibitors of thrombin as an example, we review an NMR-based experimental approach for the design of functional mimetics of protein-protein interactions. The strategy includes: (i) identification of binding residues in peptide ligands by differential resonance perturbation, (ii) determination of protein-bound structures of peptide ligands by use of transferred NOEs, (iii) minimization of larger protein and peptide ligands on the basis of NMR structural information, and (iv) linkage of two weakly binding mimetics to produce an inhibitor with enhanced affinity and specificity. This approach can be especially effective for the design of potent and selective functional mimetics of protein-protein interactions because it is less likely that the surfaces of two related proteins or enzymes share two identical binding sites or regions.Key words: NMR, protein-protein interactions, functional mimetics, bridge-binding inhibitors, thrombin.

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