A patient with subcutaneous-insulin resistance treated by insulin lispro plus heparin

2001 ◽  
Vol 54 (3) ◽  
pp. 209-212 ◽  
Author(s):  
Yoshiharu Tokuyama ◽  
Osamu Nozaki ◽  
Azuma Kanatsuka
Keyword(s):  
Insulin Resistance ◽  
Insulin Lispro ◽  
Subcutaneous Insulin

scholarly journals Case of subcutaneous insulin resistance syndrome treated with ultra‐rapid insulin lispro

2021 ◽  
Author(s):  
Takahiro Ishii ◽  
Akihiro Katayama ◽  
Mihiro Sue ◽  
Remi Kuribayashi ◽  
Masafumi Tenta ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Insulin Lispro ◽  
Insulin Resistance Syndrome ◽  
Subcutaneous Insulin

scholarly journals A Male with Extreme Subcutaneous Insulin Resistance: A Case Report

2016 ◽  
Vol 23 (2) ◽  
pp. 209-213 ◽  
Author(s):  
Zuhayer Ahmed ◽  
Indrajit Prasad ◽  
Hafizur Rahman ◽  
Jalil Ansari ◽  
Khaled Hassan
Keyword(s):  
Insulin Resistance ◽  
Blood Glucose ◽  
Underdeveloped Country ◽  
Hypoglycemic Agents ◽  
High Dose ◽  
Subcutaneous Insulin ◽  
Oral Hypoglycemic Agents ◽  
Glucose Levels ◽  
Medical Issues ◽  
Insulin Autoantibody

AbstractIntroduction: Though insulin has no upper limit in dosage, we do not encounter very high dose requirements too often. The reported case is the first in Bangladesh to require more than 1000 international units (IU) of subcutaneous insulin per day.Case presentation: A 44-year old male diabetic patient from Bangladesh presented with unusually uncontrolled diabetes mellitus due to extreme insulin resistance. Despite dramatic increase in insulin step by step up to 1110 IU of concomitant short and intermediate acting insulin per day by subcutaneous route, his blood glucose remained over 12 mmol/L persistently, in all the fasting, pre-prandial, postprandial and random samples. He was also treated with several oral hypoglycemic agents including metformin, vildagliptin, glimepiride, pioglitazone and miglitol along with insulin but blood glucose levels remained almost unchanged. However, intravenous infusion of insulin over 4 hours caused a plummet in the glucose level. His blood test for insulin autoantibody was negative.Conclusion: This paper provides a scope to review literatures on extreme subcutaneous insulin resistance and its management. It also reveals the limitations of management due to lack of facilities in an underdeveloped country, which hinders proper exploration to many medical issues.

A NOVEL USE OF U-500 INSULIN FOR CONTINUOUS SUBCUTANEOUS INSULIN INFUSION IN PATIENTS WITH INSULIN RESISTANCE: A CASE SERIES

2003 ◽  
Vol 9 (3) ◽  
pp. 181-186 ◽  
Author(s):  
Treyce S. Knee, MD, FACE ◽  
Daniel F. Seidensticker, MD ◽  
Judy L. Walton, RNC, FNP, CDE ◽  
Larissa M. Solberg, RN, CDE ◽  
David H. Lasseter, MD, FACE
Keyword(s):  
Insulin Resistance ◽  
Continuous Subcutaneous Insulin Infusion ◽  
Insulin Infusion ◽  
Case Series ◽  
Subcutaneous Insulin

Severe insulin resistance in a patient with type 1 diabetes and stiff-man syndrome treated with insulin lispro

1998 ◽  
Vol 41 (3) ◽  
pp. 197-202 ◽  
Author(s):  
Irl B Hirsch ◽  
David D'Alessio ◽  
Lily Eng ◽  
Connie Davis ◽  
Åke Lernmark ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Type 1 Diabetes ◽  
Insulin Lispro ◽  
Severe Insulin Resistance ◽  
Stiff Man Syndrome
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