Surveillance after surgical resection of lung cancer – would the LNC-PATH risk stratification score affect follow-up protocols in Royal Glamorgan Hospital?

Objective: To report the experience of a routine follow-up program based on medical visits and chest CT. Methods: This was a retrospective study involving patients followed after complete surgical resection of non-small cell lung cancer between April of 2007 and December of 2015. The follow-up program consisted of clinical examination and chest CT. Each follow-up visit was classified as a routine or non-routine consultation, and patients were considered symptomatic or asymptomatic. The outcomes of the follow-up program were no evidence of cancer, recurrence, or second primary lung cancer. Results: The sample comprised 148 patients. The median time of follow-up was 40.1 months, and 74.3% of the patients underwent fewer chest CTs than those recommended in our follow-up program. Recurrence and second primary lung cancer were found in 17.6% and 11.5% of the patients, respectively. Recurrence was diagnosed in a routine medical consultation in 69.2% of the cases, 57.7% of the patients being asymptomatic. Second primary lung cancer was diagnosed in a routine medical appointment in 94.1% of the cases, 88.2% of the patients being asymptomatic. Of the 53 patients who presented with abnormalities on chest CT, 41 (77.3%) were diagnosed with cancer. Conclusion: Most of the cases of recurrence, especially those of second primary lung cancer, were confirmed by chest CT in asymptomatic patients, indicating the importance of a strict follow-up program that includes chest CTs after surgical resection of lung cancer.

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Follow-up of local (stage I and stage II) non-small-cell lung cancer after surgical resection

Current Treatment Options in Oncology ◽

10.1007/s11864-002-0043-y ◽

2002 ◽

Vol 3 (1) ◽

pp. 67-73 ◽

Cited By ~ 6

Author(s):

Martin J. Edelman ◽

Julie Schuetz

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Surgical Resection ◽

Cell Lung Cancer ◽

Small Cell ◽

Stage I ◽

Stage Ii ◽

Small Cell Lung

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Risk Stratification in Multinodular Goiter: A Retrospective Review of Sonographic Features, Histopathological Results, and Cancer Risk

Canadian Association of Radiologists Journal ◽

10.1016/j.carj.2017.03.002 ◽

2017 ◽

Vol 68 (4) ◽

pp. 425-430 ◽

Cited By ~ 2

Author(s):

Brendan S. Kelly ◽

Pradeep Govender ◽

Michael Jeffers ◽

John Kinsella ◽

James Gibney ◽

...

Keyword(s):

Risk Stratification ◽

Multinodular Goiter ◽

Needle Aspiration ◽

Ultrasound Images ◽

Average Risk ◽

Subclinical Disease ◽

Ultrasound Findings ◽

Histopathological Results ◽

Risk Stratification Score

Purpose In the management of thyroid nodules, although the potential for malignancy exists, there is also the potential for overtreatment of subclinical disease. Although the TI-RADS (Thyroid Imaging-Reporting and Data System) system outlines a risk stratification score based on suspicious ultrasound findings, it has not been universally accepted. Many TI-RADS 2 or 3 patients proceed to fine needle aspiration biopsy (FNAB), potentially unnecessarily. The aim of the study was to identify whether lesions within a multinodular goiter (MNG) without suspicious features can be followed with ultrasound rather than biopsied as is recommended for single nodules. Methods Pathology records were retrospectively analysed for proven MNGs over a 5-year period. A total of 293 cases were identified. FNAB, prebiopsy ultrasound images, and reports were identified for each case. Images were reviewed and assessed for sonographically suspicious criteria guided by TI-RADS. Logistic regression was applied to determine if any sonographic features were associated with neoplasia. Odds ratios with 95% confidence intervals were calculated. Results Of 293 samples, 14 (4.7%) were neoplastic. Having no suspicious features conferred an average risk of 0.0339 (95% confidence interval: 0.02831-0.04087) of neoplasia. Risk of neoplasm significantly increased by having 1 and >1 suspicious feature ( P < .001). Regarding cytological results, of 237 patients with Thy-2 cytology, 159 were followed up and 8 had a neoplasm. Conclusion Ultrasound can be used to estimate risk of neoplasia in MNG. In the absence of suspicious radiological findings, follow-up with ultrasound rather than FNAB may be appropriate in patients who have a low clinical suspicion for neoplasia.

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Bronchoscopic treatment of patients with intraluminal microinvasive radiographically occult lung cancer not eligible for surgical resection: a follow-up study

Lung Cancer ◽

10.1016/s0169-5002(02)00309-4 ◽

2003 ◽

Vol 39 (1) ◽

pp. 49-53 ◽

Cited By ~ 24

Author(s):

Anton Vonk-Noordegraaf ◽

Pieter E Postmus ◽

Tom G Sutedja

Keyword(s):

Lung Cancer ◽

Surgical Resection ◽

Follow Up Study

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Improvements in French risk stratification score were correlated with reductions in mean pulmonary artery pressure in pulmonary arterial hypertension: a subanalysis of the Japan Pulmonary Hypertension Registry (JAPHR)

BMC Pulmonary Medicine ◽

10.1186/s12890-021-01398-6 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Yuichi Tamura ◽

◽

Hiraku Kumamaru ◽

Kohtaro Abe ◽

Toru Satoh ◽

...

Keyword(s):

Pulmonary Hypertension ◽

Pulmonary Arterial Hypertension ◽

Pulmonary Artery ◽

Risk Stratification ◽

Arterial Hypertension ◽

Pulmonary Artery Pressure ◽

Pulmonary Arterial ◽

The Relationship ◽

Risk Stratification Score

Abstract Background Since there was no previous report, we analyzed the relationship between French Risk Stratification parameters in pulmonary arterial hypertension (PAH) and mean pulmonary arterial pressures (mPAP) using Japan PH Registry (JAPHR) national-wide cohort. Methods We enrolled 108 patients with PAH from JAPHR from previous reported cohort and analyzed the relations between French Risk Stratification scores and hemodynamic improvements. Results The ratio meeting 0 to 4 French Risk Stratification score was 21.3%, 31.5%, 32.4%, 13.0%, and 1.9% at baseline, and 6.5%, 23.2%, 33.3%, 23.2%, 13.9% at follow-up, respectively. The improvements in the number of criteria met were associated both with mPAP at follow-up (p = 0.03) and with the improvements in mPAP (p < 0.001). Conclusion The improvements in French Risk Stratification may become a marker of improved hemodynamics including mPAP.

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Improvements in French Risk Stratification Score were Correlated with Reductions in Mean Pulmonary Artery Pressure in Pulmonary Arterial Hypertension: A Subanalysis of the Japan Pulmonary Hypertension Registry (JAPHR)

10.21203/rs.3.rs-25209/v3 ◽

2020 ◽

Author(s):

Yuichi Tamura ◽

Hiraku Kumamaru ◽

Kohtaro Abe ◽

Toru Satoh ◽

Hiroaki Miyata ◽

...

Keyword(s):

Pulmonary Hypertension ◽

Pulmonary Arterial Hypertension ◽

Pulmonary Artery ◽

Risk Stratification ◽

Arterial Hypertension ◽

Pulmonary Artery Pressure ◽

Pulmonary Arterial ◽

The Relationship ◽

Risk Stratification Score

Abstract BackgroundSince there was no previous report, we analyzed the relationship between French Risk Stratification parameters in pulmonary arterial hypertension (PAH) and mean pulmonary arterial pressures (mPAP) using Japan PH Registry (JAPHR) national-wide cohort.MethodsWe enrolled 108 patients with PAH from JAPHR from previous reported cohort and analyzed the relations between French Risk Stratification scores and hemodynamic improvements.ResultsThe ratio meeting 0 to 4 French Risk Stratification score was 21.3%, 31.5%, 32.4%, 13.0%, and 1.9% at baseline, and 6.5%, 23.2%, 33.3%, 23.2%, 13.9% at follow-up, respectively. The improvements in the number of criteria met were associated both with mPAP at follow-up (p=0.03) and with the improvements in mPAP (p<0.001).ConclusionThe improvements in French Risk Stratification may become a marker of improved hemodynamics including mPAP.

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