Contingent negative variation, extraversion, reaction time and drug effects

2001 ◽  
Vol 30 (7) ◽  
pp. 1083-1094 ◽  
Author(s):  
P.F Werre ◽  
H Mattie ◽  
E.W Berretty
Sangyo Igaku ◽  
1991 ◽  
Vol 33 (3) ◽  
pp. 170-178
Author(s):  
Heihachiro ARITO ◽  
Masaya TAKAHASHI

Science ◽  
1980 ◽  
Vol 208 (4448) ◽  
pp. 1165-1168 ◽  
Author(s):  
JW Rohrbaugh ◽  
K Syndulko ◽  
TF Sanquist ◽  
DB Lindsley

Slow shifts in brain potential (commonly called the contingent negative variation), obtained during a warned reaction-time task with a foreperiod of 1 second, were compared with waveforms synthesized by the addition of separately obtained potentials associated with individual (nonpaired) sensory stimuli and self-initiated motor movements. The synthesized waveforms match closely the actual contingent negative variation, suggesting that it is constituted largely of separate, noncontingent elements related to sensory and motor processes.


1987 ◽  
Vol 18 (3) ◽  
pp. 149-154 ◽  
Author(s):  
R. Zappoli ◽  
G. Arnetoli ◽  
M. Paganini ◽  
A. Versari ◽  
A. Battaglia ◽  
...  

1992 ◽  
Vol 160 (5) ◽  
pp. 647-653 ◽  
Author(s):  
David J. King ◽  
Geraldine Henry

The effects of haloperidol (1 mg), benzhexol (5 mg), diazepam (10 mg) and caffeine (400 mg) on subjective and objective measures of cognitive and psychomotor function were compared with placebo in 20 healthy volunteers. While both diazepam and benzhexol were associated with highly significant impairments in subjective alertness, critical flicker fusion threshold and choice reaction time (CRT), haloperidol could not be distinguished from placebo in most tests but was actually associated with an apparent improvement in CRT (in males) and simple visual reaction time. The perceptual maze test detected impairment by benzhexol on processing speed but was not sensitive to any other drug effects. Multiple-dose studies are required to establish if there is a true activating effect of haloperidol using a test of sustained attention. No effect of Eysenck personality subtype or life events on baseline or drug response data was detected.


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