Safety and immunogenicity of a trivalent, inactivated, mammalian cell culture-derived influenza vaccine in healthy adults, seniors, and children

Scott A Halperin; Bruce Smith; Taoufik Mabrouk; Marc Germain; Pierre Trépanier; Thomas Hassell; John Treanor; Richard Gauthier; Elaine L Mills

doi:10.1016/s0264-410x(01)00428-5

Safety and immunogenicity of a trivalent, inactivated, mammalian cell culture-derived influenza vaccine in healthy adults, seniors, and children

Vaccine ◽

10.1016/s0264-410x(01)00428-5 ◽

2002 ◽

Vol 20 (7-8) ◽

pp. 1240-1247 ◽

Cited By ~ 75

Author(s):

Scott A Halperin ◽

Bruce Smith ◽

Taoufik Mabrouk ◽

Marc Germain ◽

Pierre Trépanier ◽

...

Keyword(s):

Cell Culture ◽

Influenza Vaccine ◽

Mammalian Cell ◽

Mammalian Cell Culture ◽

Healthy Adults

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A New Mammalian Cell Culture-Derived Influenza Vaccine is as Safe as, and Immunogenically Non-Inferior to, an Egg-Based Influenza Vaccine

International Journal of Infectious Diseases ◽

10.1016/j.ijid.2008.05.384 ◽

2008 ◽

Vol 12 ◽

pp. e155

Author(s):

A. Szymczakiewicz-Multanowska ◽

A. Izu ◽

M.V. Sparacio ◽

M. Lattanzi ◽

N. Groth

Keyword(s):

Cell Culture ◽

Influenza Vaccine ◽

Mammalian Cell ◽

Mammalian Cell Culture

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A phase III, open-label, single-arm, study to evaluate the safety and immunogenicity of a trivalent, surface antigen inactivated subunit influenza virus vaccine produced in mammalian cell culture (Optaflu®) in healthy adults

Infection ◽

10.1007/s15010-018-1233-2 ◽

2018 ◽

Vol 47 (1) ◽

pp. 105-109 ◽

Cited By ~ 2

Author(s):

Micha Loebermann ◽

Carlos Fritzsche ◽

Hilte Geerdes-Fenge ◽

Esther Heijnen ◽

Daniel Kirby ◽

...

Keyword(s):

Cell Culture ◽

Influenza Virus ◽

Mammalian Cell ◽

Surface Antigen ◽

Virus Vaccine ◽

Mammalian Cell Culture ◽

Influenza Virus Vaccine ◽

Healthy Adults ◽

Phase Iii ◽

Open Label

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Safety and immunogenicity of a new influenza vaccine grown in mammalian cell culture

Vaccine ◽

10.1016/s0264-410x(98)00011-5 ◽

1998 ◽

Vol 16 (13) ◽

pp. 1331-1335 ◽

Cited By ~ 23

Author(s):

S Halperin

Keyword(s):

Cell Culture ◽

Influenza Vaccine ◽

Mammalian Cell ◽

Mammalian Cell Culture

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Immunogenicity, Safety and Reactogenicity of a Mammalian Cell-Culture–Derived Influenza Vaccine in Healthy Children and Adolescents Three to Seventeen Years of Age

The Pediatric Infectious Disease Journal ◽

10.1097/inf.0b013e31824bb179 ◽

2012 ◽

Vol 31 (5) ◽

pp. 494-500 ◽

Cited By ~ 24

Author(s):

Timo Vesikari ◽

Stan L. Block ◽

Fernando Guerra ◽

Maria Lattanzi ◽

Sandra Holmes ◽

...

Keyword(s):

Cell Culture ◽

Influenza Vaccine ◽

Children And Adolescents ◽

Mammalian Cell ◽

Mammalian Cell Culture ◽

Healthy Children

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Faculty Opinions recommendation of A phase III, open-label, single-arm, study to evaluate the safety and immunogenicity of a trivalent, surface antigen inactivated subunit influenza virus vaccine produced in mammalian cell culture (Optaflu®) in healthy adults.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.737784494.793573737 ◽

2020 ◽

Author(s):

Graham Pawelec

Keyword(s):

Cell Culture ◽

Influenza Virus ◽

Mammalian Cell ◽

Surface Antigen ◽

Virus Vaccine ◽

Mammalian Cell Culture ◽

Influenza Virus Vaccine ◽

Healthy Adults ◽

Phase Iii ◽

Open Label

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A novel mammalian cell-culture technique for consistent production of a well-tolerated and immunogenic trivalent subunit influenza vaccine

Vaccine ◽

10.1016/j.vaccine.2009.07.083 ◽

2009 ◽

Vol 27 (43) ◽

pp. 6022-6029 ◽

Cited By ~ 19

Author(s):

Arvydas Ambrozaitis ◽

Nicola Groth ◽

Roberto Bugarini ◽

Vittoria Sparacio ◽

Audino Podda ◽

...

Keyword(s):

Cell Culture ◽

Influenza Vaccine ◽

Mammalian Cell ◽

Mammalian Cell Culture ◽

Culture Technique ◽

Cell Culture Technique

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Clinical Trial to Evaluate the Safety and Immunogenicity of a Trivalent Surface Antigen Seasonal Influenza Vaccine Produced in Mammalian Cell Culture and Administered to Young and Elderly Adults with and without A(H1N1) Pre-Vaccination

PLoS ONE ◽

10.1371/journal.pone.0070866 ◽

2013 ◽

Vol 8 (8) ◽

pp. e70866 ◽

Cited By ~ 11

Author(s):

Micha Loebermann ◽

Ulrich Voss ◽

Seetha Meyer ◽

Dietrich Bosse ◽

Carlos Fritzsche ◽

...

Keyword(s):

Clinical Trial ◽

Cell Culture ◽

Influenza Vaccine ◽

Mammalian Cell ◽

Surface Antigen ◽

Seasonal Influenza ◽

Mammalian Cell Culture ◽

Elderly Adults ◽

Seasonal Influenza Vaccine

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Safety, tolerability and immunogenicity of a mammalian cell-culture-derived influenza vaccine: A sequential Phase I and Phase II clinical trial

Vaccine ◽

10.1016/j.vaccine.2008.11.003 ◽

2009 ◽

Vol 27 (5) ◽

pp. 786-791 ◽

Cited By ~ 35

Author(s):

N. Groth ◽

E. Montomoli ◽

C. Gentile ◽

I. Manini ◽

R. Bugarini ◽

...

Keyword(s):

Clinical Trial ◽

Cell Culture ◽

Influenza Vaccine ◽

Phase I ◽

Mammalian Cell ◽

Phase Ii ◽

Mammalian Cell Culture ◽

Phase Ii Clinical Trial ◽

Sequential Phase

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Immunogenicity and safety of an inactivated 2012/2013 trivalent influenza vaccine produced in mammalian cell culture (Optaflu®)

Human Vaccines & Immunotherapeutics ◽

10.4161/hv.27140 ◽

2013 ◽

Vol 10 (2) ◽

pp. 441-448 ◽

Cited By ~ 10

Author(s):

Christof David Vinnemeier ◽

Johanna Fischer-Herr ◽

Seetha Meyer ◽

Katja Liebig ◽

Wiebke Theeß ◽

...

Keyword(s):

Cell Culture ◽

Influenza Vaccine ◽

Mammalian Cell ◽

Mammalian Cell Culture ◽

Trivalent Influenza Vaccine

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Safety, Tolerability and Immunogenicity of an Trivalent Inactivated Cell-Culture Influenza Vaccine in Healthy Adults

Case Medical Research ◽

10.31525/ct1-nct03893669 ◽

2019 ◽

Author(s):

Keyword(s):

Cell Culture ◽

Influenza Vaccine ◽

Healthy Adults

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