Molecular and functional characterization of galectin 9 mRNA isoforms in porcine and human cells and tissues***The nucleotide sequences reported in this paper have been submitted to the GenBankTM / EBI Data Bank with accession number(s) AJ131826 (Sus scrofa mRNA for urate transporter/channel protein) and AJ131827 (Sus scrofa mRNA for urate transporter/channel isoform).

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Abstract Together with genome analysis and knock-out mutants, structural and functional characterization of proteins provide valuable hints on the biology of the organism under investigation. Structural characterization can be achieved by techniques such as X-ray crystallography, NMR, Cryo-EM. The information derived from the structure are a good starting point to comprehend the details of the proteins molecular function for a better understanding of their biological role. This review aims at describing the progress in the structural and functional characterization of proteins from the plant pathogen Erwinia amylovora obtained by structural biology and currently deposited in the Protein Data Bank.


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Selectivity of a PFI-1 based BET bromodomain probe was demonstrated using affinity capture in nuclear extracts from human cells.


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