Estimation of uncertainty in multi-level in silico models predicting biomarkers of drug-induced proarrhythmic risk

2021 ◽  
Vol 350 ◽  
pp. S64-S65
Author(s):  
K. Kopanska ◽  
J.C. Gómez-Tamayo ◽  
J. Llopis-Lorente ◽  
B.A. Trenor-Gomis ◽  
J. Sáiz ◽  
...  
Keyword(s):  
In Silico ◽  
Drug Induced ◽  
Proarrhythmic Risk ◽  
Multi Level ◽  
In Silico Models ◽  
Estimation Of Uncertainty

scholarly journals The development and application of in silico models for drug induced liver injury

RSC Advances ◽  
2018 ◽  
Vol 8 (15) ◽  
pp. 8101-8111 ◽  
Author(s):  
Xiao Li ◽  
Yaojie Chen ◽  
Xinrui Song ◽  
Yuan Zhang ◽  
Huanhuan Li ◽  
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Keyword(s):  
Pharmaceutical Industry ◽  
Liver Injury ◽  
In Silico ◽  
Nutritional Supplements ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
In Silico Models

Drug-induced liver injury (DILI), caused by drugs, herbal agents or nutritional supplements, is a major issue for patients and the pharmaceutical industry.

Evaluation of four in silico biomarkers for drug-induced proarrhythmic risk: COVID-19 off-label therapies case study

2021 ◽  
Vol 111 ◽  
pp. 107052
Author(s):  
Elisa Passini ◽  
Xin Zhou ◽  
Cristian Trovato ◽  
Annie Delaunois ◽  
Jean-Pierre Valentin ◽  
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Keyword(s):  
In Silico ◽  
Drug Induced ◽  
Off Label ◽  
Proarrhythmic Risk

scholarly journals In silico models for evaluating proarrhythmic risk of drugs

2020 ◽  
Vol 4 (2) ◽  
pp. 021502
Author(s):  
Minki Hwang ◽  
Chul-Hyun Lim ◽  
Chae Hun Leem ◽  
Eun Bo Shim
Keyword(s):  
In Silico ◽  
Proarrhythmic Risk ◽  
In Silico Models

scholarly journals In Silico QT and APD Prolongation Assay for Early Screening of Drug-Induced Proarrhythmic Risk

2018 ◽  
Vol 58 (4) ◽  
pp. 867-878 ◽  
Author(s):  
Lucia Romero ◽  
Jordi Cano ◽  
Julio Gomis-Tena ◽  
Beatriz Trenor ◽  
Ferran Sanz ◽  
...  
Keyword(s):  
In Silico ◽  
Early Screening ◽  
Drug Induced ◽  
Proarrhythmic Risk
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