Determination of glutamate and aspartate in microdialysis samples by reversed-phase column liquid chromatography with fluorescence and electrochemical detection

Author(s):  
Jan Kehr
1979 ◽  
Vol 25 (12) ◽  
pp. 2043-2045 ◽  
Author(s):  
J L Morrisey ◽  
Z K Shihabi

Abstract We describe a method for the assay of urinary 4-hydroxy-3-methoxymandelic acid (vanillylmandelic acid) based on separation on a microparticulate reversed-phase column and direct electrochemical detection. The method can be used after extraction from urine or by direct urine injection after 100-fold dilution.


1979 ◽  
Vol 25 (12) ◽  
pp. 2045-2047 ◽  
Author(s):  
J L Morrisey ◽  
Z K Shihabi

Abstract We describe a method for the assay of urinary 4-hydroxy-3-methoxyphenylacetic acid (homovanillic acid), based on its separation on a microparticulate reversed-phase column and direct electrochemical detection. Patients with neuroblastoma, pheochromocytoma, and Parkinson's disease have increased amounts of this compound in their urine.


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