The Eve effect in the Penna model of biological ageing

1999 ◽  
Vol 273 (1-2) ◽  
pp. 169-181 ◽  
Author(s):  
Danuta Makowiec ◽  
Jakub Da̧bkowski ◽  
Małgorzata Groth
Keyword(s):  
Biological Ageing ◽  
Penna Model

Strategies of Reproduction and Longevity

1998 ◽  
Vol 09 (06) ◽  
pp. 787-791 ◽  
Author(s):  
M. Argollo de Menezes ◽  
A. Racco ◽  
T. J. P. Penna
Keyword(s):  
Computer Simulations ◽  
Mutation Accumulation ◽  
Biological Ageing ◽  
Penna Model

In this work we try to verify whether the increased lifespan of trees and some lobsters, like Homarus, whose fertility increases with advancing age, can be explained by the mutation accumulation theory of biological ageing. Computer simulations of the Penna model seems to support this hypothesis, showing that it is a robust strategy of reproduction.

Biological ageing with birth rate controlled by mutations in the Penna model

2000 ◽  
Vol 119 (2) ◽  
pp. 139-144 ◽  
Author(s):  
M. Magdoń-Maksymowicz ◽  
A. Z. Maksymowicz ◽  
K. Kułakowski
Keyword(s):  
Birth Rate ◽  
Biological Ageing ◽  
Penna Model ◽  
Rate Controlled

AGE-OF-PARENT DEPENDENT MUTATION RATE AND WEAK CHILDREN IN THE PENNA MODEL IN BIOLOGICAL AGEING

1996 ◽  
Vol 07 (05) ◽  
pp. 731-737 ◽  
Author(s):  
K. NIKOLAJ BERNTSEN
Keyword(s):  
Mutation Rate ◽  
High Mortality ◽  
Biological Ageing ◽  
Age Dependent ◽  
Penna Model

We investigate the effect of an age-dependent mutation rate in the Penna model of ageing and then we observe that the high mortality for human babies can be reproduced by the model if one assumes babies to be weaker than adults.

PROBABILISTIC GENERALIZATION OF PENNA AGEING MODEL AND THE OLDEST OLD

1999 ◽  
Vol 10 (07) ◽  
pp. 1363-1365 ◽  
Author(s):  
D. STAUFFER
Keyword(s):  
Oldest Old ◽  
Demographic Data ◽  
Absolute Maximum ◽  
Maximum Life Span ◽  
Monte Carlo Data ◽  
Biological Ageing ◽  
Probabilistic Generalization ◽  
Ageing Model ◽  
Penna Model ◽  
Rich Countries

Using a 1995 method of Thoms et al., the traditional Penna model of biological ageing is modified such that there is no more absolute maximum life span; instead, our Monte Carlo data are similar to real demographic data collected by Thatcher et al., for rich countries.

MONTE CARLO SIMULATION OF AGEING: BEYOND BIT-STRING MODELS

1996 ◽  
Vol 06 (06) ◽  
pp. 789-806 ◽  
Author(s):  
AMERICO T. BERNARDES ◽  
DIETRICH STAUFFER
Keyword(s):  
Monte Carlo Simulation ◽  
Monte Carlo ◽  
Population Size ◽  
String Model ◽  
Deleterious Mutations ◽  
Approach To Equilibrium ◽  
Biological Ageing ◽  
Penna Model ◽  
String Models ◽  
Mutational Meltdown

Penna's bit-string model of biological ageing due to the accumulation of deleterious mutations is generalized to allow for more than one disease per year. The results remain qualitatively unchanged except for a more complicated non-monotonic approach to equilibrium. We also look at "mutational meltdown", the extinction of the whole population if all mutations are deleterious and heritable, and why the Penna model can escape this extinction. No dependence on population size is found for mutational meltdown, with up to 108 individuals.

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