FRI-251-Impact of hepatitis C treatment on patterns of drug use and subsequent treatment outcomes: High SVR rates despite increasing intravenous drug use in the post treatment period

2019 ◽  
Vol 70 (1) ◽  
pp. e504-e505
Author(s):  
Trina Ritchie ◽  
Alison Boyle ◽  
Fiona Marra ◽  
Erica Peters ◽  
John Campbell ◽  
...  
2019 ◽  
Vol 4 ◽  
Author(s):  
G. Gioula ◽  
E. Sinakos ◽  
E. Gigi ◽  
I. Goulis ◽  
T. Vasiliadis ◽  
...  

Abstract Hepatitis C virus (HCV) represents a major public health problem, while the identification of a HCV genotype is clinically very important for therapy prescription. The aim of the present study was to determine the HCV genotype distribution patients from northern Greece with HCV RNA positive viral load and to identify whether there is a shift in this distribution, during 2009–2017. The study was performed on 915 HCV positive patients and according to the results, genotype 3 was the most prevalent genotype (Ν = 395, 43.2%) followed by genotype 1 (Ν = 361, 39.5%). Regarding the gender of the patients, genotype 1 was mostly detected in women. Moreover, genotype 1 was associated with higher viral loads, while genotype 3 was most frequently detected in patients with a history of intravenous drug use. In conclusion, our results show that genotype 3 is the most prevalent genotype in Greece during the last decade as opposed to older epidemiological studies, likely due to intravenous drug use becoming the major source of infection.


2011 ◽  
Vol 140 (5) ◽  
pp. S-456
Author(s):  
Hossein Poustchi ◽  
Saeed Esmaili ◽  
Ashraf Mohammadkhani ◽  
Aghbibi Nikmahzar ◽  
Shahin Merat ◽  
...  

2010 ◽  
Vol 30 (10) ◽  
pp. 1454-1460 ◽  
Author(s):  
Spilios Manolakopoulos ◽  
Melanie J. Deutsch ◽  
Olga Anagnostou ◽  
Stelios Karatapanis ◽  
Elli Tiniakou ◽  
...  

2014 ◽  
Vol 134 ◽  
pp. 222-227
Author(s):  
Marcia Russell ◽  
Mary Patricia Pauly ◽  
Charles Denton Moore ◽  
Constance Chia ◽  
Jennifer Mary Dorrell ◽  
...  

2008 ◽  
Vol 13 (21) ◽  
Author(s):  
A Duberg ◽  
R Janzon ◽  
E Bäck ◽  
K Ekdahl ◽  
A Blaxhult

In Sweden, infection with hepatitis C virus (HCV) has been a notifiable disease since 1990, when diagnostic methods became available. Blood donor screening indicated that about 0.5% of the Swedish population (9 millions) had been HCV infected. Here we present the Swedish hepatitis C epidemic based on data from all the HCV notifications 1990-2006. During this time about 42,000 individuals (70% men) were diagnosed and reported as HCV infected. The majority (80%) were born in 1950 or later, with a high percentage (60%) born in the 1950s and 1960s. Younger people, 15-24 years old at notification, were reported on the same level each year. The main reported routes of HCV transmission were intravenous drug use in 65%, blood transfusions/products in 6%, and sexual in 2%, though unknown or not stated in 26%. Approximately 6,000 of all notified individuals have died during the study period. To conclude, the Swedish HCV epidemic is highly related to the increase of intravenous drug use in the late 1960s and 1970s, with a high proportion of people now chronically infected for more than 25 years, resulting in an increase of severe liver complications in form of cirrhosis and hepatocellular carcinoma. Furthermore the unchanged number of notifications of newly infected younger people indicates an ongoing HCV epidemic.


2012 ◽  
Vol 12 (1) ◽  
pp. 9-10 ◽  
Author(s):  
Mehdi Zobeiri ◽  
Mehdi Zobeiri ◽  
Peyman Adibi ◽  
Peyman Adibi ◽  
Seyed Moayed Alavian ◽  
...  

2012 ◽  
Vol 12 (01) ◽  
pp. 09-10 ◽  
Author(s):  
Mehdi Zobeiri ◽  
Peyman Adibi ◽  
Seyed Moayed Alavian

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