EFFECTS OF RN316 (PF-04950615), A HUMANIZED IGG2ΔA MONOCLONAL ANTIBODY BINDING PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9, ON LIPOPROTEIN PARTICLES IN HYPERCHOLESTEROLEMIC SUBJECTS

Hong Wan; Barry Gumbiner; Tenshang Joh; Chandrasekhar Udata; Philippe Forgues; Pamela D. Garzone

doi:10.1016/s0735-1097(13)61387-x

EFFECTS OF RN316 (PF-04950615), A HUMANIZED IGG2ΔA MONOCLONAL ANTIBODY BINDING PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9, ON LIPOPROTEIN PARTICLES IN HYPERCHOLESTEROLEMIC SUBJECTS

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(13)61387-x ◽

2013 ◽

Vol 61 (10) ◽

pp. E1387 ◽

Cited By ~ 3

Author(s):

Hong Wan ◽

Barry Gumbiner ◽

Tenshang Joh ◽

Chandrasekhar Udata ◽

Philippe Forgues ◽

...

Keyword(s):

Monoclonal Antibody ◽

Antibody Binding ◽

Proprotein Convertase ◽

Lipoprotein Particles ◽

Hypercholesterolemic Subjects ◽

Monoclonal Antibody Binding

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The effects of single- and multiple-dose administration of bococizumab (RN316/PF-04950615), a humanized IgG2Δa monoclonal antibody binding proprotein convertase subtilisin/kexin type 9, in hypercholesterolemic subjects treated with and without atorvastati

Cardiovascular Therapeutics ◽

10.1111/1755-5922.12309 ◽

2017 ◽

Vol 36 (1) ◽

pp. e12309 ◽

Cited By ~ 5

Author(s):

Barry Gumbiner ◽

Tenshang Joh ◽

Hong Liang ◽

Hong Wan ◽

Matteo Levisetti ◽

...

Keyword(s):

Monoclonal Antibody ◽

Multiple Dose ◽

Antibody Binding ◽

Proprotein Convertase ◽

Dose Administration ◽

Multiple Dose Administration ◽

Hypercholesterolemic Subjects ◽

Monoclonal Antibody Binding

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IgE and monoclonal antibody binding by the mite allergen Der p 7

Clinical & Experimental Allergy ◽

10.1046/j.1365-2222.1996.d01-318.x ◽

1996 ◽

Vol 26 (3) ◽

pp. 308-315 ◽

Cited By ~ 1

Author(s):

H.-D. SHEN ◽

K. Y. CHUA ◽

W. L. LIN ◽

H. L. CHEN ◽

K.-H. HSIEH ◽

...

Keyword(s):

Monoclonal Antibody ◽

Mite Allergen ◽

Antibody Binding ◽

Monoclonal Antibody Binding

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Lipid-dependent recovery of alpha-bungarotoxin and monoclonal antibody binding to the purified alpha-subunit from Torpedo marmorata acetylcholine receptor. Enhancement by noncompetitive channel blockers.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)90892-6 ◽

1984 ◽

Vol 259 (18) ◽

pp. 11512-11519

Author(s):

S J Tzartos ◽

J P Changeux

Keyword(s):

Monoclonal Antibody ◽

Acetylcholine Receptor ◽

Antibody Binding ◽

Alpha Subunit ◽

Channel Blockers ◽

Torpedo Marmorata ◽

Alpha Bungarotoxin ◽

Monoclonal Antibody Binding

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The role of adsorbed fibrinogen in platelet adhesion to polyurethane surfaces: A comparison of surface hydrophobicity, protein adsorption, monoclonal antibody binding, and platelet adhesion

Journal of Biomedical Materials Research Part A ◽

10.1002/jbm.a.30381 ◽

2005 ◽

Vol 74A (4) ◽

pp. 722-738 ◽

Cited By ~ 144

Author(s):

Yuguang Wu ◽

Felix I. Simonovsky ◽

Buddy D. Ratner ◽

Thomas A. Horbett

Keyword(s):

Monoclonal Antibody ◽

Protein Adsorption ◽

Platelet Adhesion ◽

Surface Hydrophobicity ◽

Antibody Binding ◽

Monoclonal Antibody Binding

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Conformational changes at the active site of adenylate kinase detected using a fluorescent probe and monoclonal antibody binding

Biochimie ◽

10.1016/s0300-9084(02)01384-6 ◽

2002 ◽

Vol 84 (4) ◽

pp. 335-339 ◽

Cited By ~ 8

Author(s):

Tian-Hong Zhang ◽

Jie Luo ◽

Jun-Mei Zhou

Keyword(s):

Monoclonal Antibody ◽

Fluorescent Probe ◽

Conformational Changes ◽

Active Site ◽

Adenylate Kinase ◽

Antibody Binding ◽

Monoclonal Antibody Binding

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NMR studies of flexible opiate conformations at monoclonal antibody binding sites I. transferred nuclear overhauser effects show bound conformations

Biochemical and Biophysical Research Communications ◽

10.1016/s0006-291x(86)80182-6 ◽

1986 ◽

Vol 141 (3) ◽

pp. 1267-1273 ◽

Cited By ~ 16

Author(s):

Jay A. Glasel ◽

Philip N. Borer

Keyword(s):

Monoclonal Antibody ◽

Binding Sites ◽

Antibody Binding ◽

Nmr Studies ◽

Nuclear Overhauser ◽

Nuclear Overhauser Effects ◽

Monoclonal Antibody Binding

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Physical Studies of α-βγ Subunit Interactions of the Rod Outer Segment G Protein, G t : Effects of Monoclonal Antibody Binding

Sensory Transduction ◽

10.1007/978-1-4684-5841-1_11 ◽

1990 ◽

pp. 147-156 ◽

Cited By ~ 1

Author(s):

M. R. Mazzoni ◽

H. E. Hamm

Keyword(s):

Monoclonal Antibody ◽

G Protein ◽

Outer Segment ◽

Antibody Binding ◽

Protein G ◽

Subunit Interactions ◽

Rod Outer Segment ◽

Monoclonal Antibody Binding

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Enhancing Effect of C1q on IgG Monoclonal Antibody Binding to Hapten

International Archives of Allergy and Immunology ◽

10.1159/000235097 ◽

1990 ◽

Vol 91 (1) ◽

pp. 103-107 ◽

Cited By ~ 1

Author(s):

Atsuo Hamada ◽

Naohiro Watanabe ◽

Takachika Azuma ◽

Akio Kobayashi

Keyword(s):

Monoclonal Antibody ◽

Antibody Binding ◽

Enhancing Effect ◽

Monoclonal Antibody Binding

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Determination of a Monoclonal Antibody Binding Activity Using ImmunoDetection

Analytical Biochemistry ◽

10.1006/abio.1994.1115 ◽

1994 ◽

Vol 217 (2) ◽

pp. 241-247 ◽

Cited By ~ 6

Author(s):

M.A. Schenerman ◽

T.J. Collins

Keyword(s):

Monoclonal Antibody ◽

Binding Activity ◽

Antibody Binding ◽

Monoclonal Antibody Binding

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Quantitative analysis of monoclonal antibody binding to individual mononuclear phagocytes

Mononuclear Phagocytes ◽

10.1007/978-94-009-5020-7_6 ◽

1985 ◽

pp. 49-58

Author(s):

P. H. Nibbering ◽

P. C. J. Leijh ◽

R. van Furth

Keyword(s):

Monoclonal Antibody ◽

Quantitative Analysis ◽

Antibody Binding ◽

Mononuclear Phagocytes ◽

Monoclonal Antibody Binding

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