P.2.09 Effects of direct and indirect GABAB receptor agonists in animal models of depression and anxiety

2007 ◽  
Vol 17 ◽  
pp. S46-S47 ◽  
Author(s):  
M. Frankowska ◽  
A. Golda ◽  
K. Wydra ◽  
M. Filip ◽  
E. Przegalinski
Keyword(s):  
Animal Models ◽  
Gabab Receptor ◽  
Depression And Anxiety ◽  
Receptor Agonists ◽  
Animal Models Of Depression

Repeated exposure to chlorpyrifos alters the performance of adolescent male rats in animal models of depression and anxiety

2011 ◽  
Vol 32 (4) ◽  
pp. 355-361 ◽  
Author(s):  
Wen-Qiang Chen ◽  
Li Yuan ◽  
Rui Xue ◽  
Yun-Feng Li ◽  
Rui-Bin Su ◽  
...  
Keyword(s):  
Animal Models ◽  
Repeated Exposure ◽  
Male Rats ◽  
Adolescent Male ◽  
Depression And Anxiety ◽  
Animal Models Of Depression

Animal models of depression and anxiety: What do they tell us about human condition?

2011 ◽  
Vol 35 (6) ◽  
pp. 1357-1375 ◽  
Author(s):  
I.D. Neumann ◽  
G. Wegener ◽  
J.R. Homberg ◽  
H. Cohen ◽  
D.A. Slattery ◽  
...  
Keyword(s):  
Animal Models ◽  
Human Condition ◽  
Depression And Anxiety ◽  
Animal Models Of Depression

Preclinical evidence for the role of serotonin receptor-subtypes in depression

1992 ◽  
Vol 4 (2) ◽  
pp. 40-45
Author(s):  
B. Olivier ◽  
J. Schipper ◽  
J.A.M. van der Heyden ◽  
A. van Hest ◽  
J. Mos ◽  
...  
Keyword(s):  
Animal Models ◽  
Clinical Research ◽  
Serotonin Receptor ◽  
Antidepressant Effect ◽  
Receptor Subtypes ◽  
Research Support ◽  
Receptor Agonists ◽  
Animal Models Of Depression ◽  
Literature Evidence

SummarySerotonin (5-HT) plays an important role in depression and specific 5-HT reuptake blockers appear to be clinically important antidepressants. It is unclear however, which serotonergic mechanism is involved in the antidepressant effect, certainly when regarding the existence of at least seven 5-HT receptor subtypes. By testing different 5-HT ligands in two animal models of depression (forced swimming and DRL72-S test) and comparison with data from literature, evidence is provided for potential antidepressant qualities of 5-HT1A receptor-agonists and 5-HT1C receptor-antagonists. Compounds binding to 5-HT1B, 5-HT2 and 5-HT3 receptors do not have an antidepressant profile. Results of clinical research support the predicted antidepressive effects of 5-HT1A receptor-agonists.

scholarly journals Effects of Chronic D-Serine Elevation on Animal Models of Depression and Anxiety-Related Behavior

PLoS ONE ◽  
2013 ◽  
Vol 8 (6) ◽  
pp. e67131 ◽  
Author(s):  
David-Marian Otte ◽  
Maria Luisa Barcena de Arellano ◽  
Andras Bilkei-Gorzo ◽  
Önder Albayram ◽  
Sophie Imbeault ◽  
...  
Keyword(s):  
Animal Models ◽  
Depression And Anxiety ◽  
Animal Models Of Depression

Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: Relevance for neuropsychiatric disorders

2009 ◽  
Vol 198 (1) ◽  
pp. 83-90 ◽  
Author(s):  
Ana M. Basso ◽  
Natalie A. Bratcher ◽  
Richard R. Harris ◽  
Michael F. Jarvis ◽  
Michael W. Decker ◽  
...  
Keyword(s):  
Animal Models ◽  
Knockout Mice ◽  
P2x7 Receptor ◽  
Neuropsychiatric Disorders ◽  
Depression And Anxiety ◽  
Behavioral Profile ◽  
Animal Models Of Depression

5-Hydroxytryptamine1AReceptor Agonists in Animal Models of Depression and Anxiety

1992 ◽  
Vol 71 (1) ◽  
pp. 24-30 ◽  
Author(s):  
Wojciech Kostowski ◽  
Wanda Dyr ◽  
Pawel Krzascik ◽  
Torbjörn Järbe ◽  
Trevor Archer
Keyword(s):  
Animal Models ◽  
Depression And Anxiety ◽  
Animal Models Of Depression

Increased levels of cocaine and amphetamine regulated transcript in two animal models of depression and anxiety

2009 ◽  
Vol 34 (2) ◽  
pp. 375-380 ◽  
Author(s):  
Sara Wiehager ◽  
Daniela I. Beiderbeck ◽  
Susanne H.M. Gruber ◽  
Aram El-Khoury ◽  
Jackie Wamsteeker ◽  
...  
Keyword(s):  
Animal Models ◽  
Depression And Anxiety ◽  
Animal Models Of Depression
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