P.3.b.011 Association study of transforming growth factor-beta gene polymorphisms in schizophrenia

2013 ◽  
Vol 23 ◽  
pp. S435-S436
Author(s):  
P. Kapelski ◽  
M. Skibinska ◽  
J. Hauser
Keyword(s):  
Growth Factor ◽  
Association Study ◽  
Transforming Growth Factor Beta ◽  
Gene Polymorphisms ◽  
Transforming Growth Factor ◽  
Growth Factor Beta ◽  
Beta Gene

scholarly journals Family association study of Transforming Growth Factor-Beta 1 gene polymorphisms in schizophrenia

2016 ◽  
Vol 50 (4) ◽  
pp. 761-770 ◽  
Author(s):  
Paweł Kapelski ◽  
Maria Skibińska ◽  
Małgorzata Maciukiewicz ◽  
Dorota Zaremba ◽  
Maria Jasiak ◽  
...  
Keyword(s):  
Growth Factor ◽  
Association Study ◽  
Transforming Growth Factor Beta ◽  
Gene Polymorphisms ◽  
Transforming Growth Factor ◽  
Growth Factor Beta

scholarly journals Trastuzumab treatment is associated with elevated transforming growth factor beta gene expression.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Gene Expression ◽  
Growth Factor ◽  
Transforming Growth Factor Beta ◽  
Human Breast Cancer ◽  
Transforming Growth Factor ◽  
Expression Data ◽  
Human Breast ◽  
Trastuzumab Treatment ◽  
Growth Factor Beta ◽  
Beta Gene

The transforming growth factor beta superfamily, as its name implies, is critical for oncogenesis in multiple cellular contexts (1-8). We found, through mining published microarray and multiplexed gene expression data (9-11), that administration of trastuzumab was associated with increased expression of TGFBR1 and TGFBI. These data serve as one piece of evidence arguing against the use of trastuzumab in human breast cancer, a patient population already prone to difficult-to-treat metastases (12-15).

Sign in / Sign up

Export Citation Format

Share Document