scholarly journals The role of cadherins during primordial germ cell migration and early gonad formation in the mouse

2000 ◽  
Vol 91 (1-2) ◽  
pp. 143-152 ◽  
Author(s):  
Michael R Bendel-Stenzel ◽  
Miranda Gomperts ◽  
Robert Anderson ◽  
Janet Heasman ◽  
Christopher Wylie
Keyword(s):  
Cell Migration ◽  
Germ Cell ◽  
Primordial Germ Cell ◽  
Germ Cell Migration

scholarly journals Evidence for a role of matrix metalloproteinases and their inhibitors in primordial germ cell migration

Andrology ◽  
2013 ◽  
Vol 1 (5) ◽  
pp. 779-786 ◽  
Author(s):  
A. Díez-Torre ◽  
M. Díaz-Núñez ◽  
C. Eguizábal ◽  
U. Silván ◽  
J. Aréchaga
Keyword(s):  
Cell Migration ◽  
Matrix Metalloproteinases ◽  
Germ Cell ◽  
Primordial Germ Cell ◽  
Germ Cell Migration

scholarly journals Primordial Germ Cell Migration in the Rat: Preliminary Evidence for a Role of Galactosyltransferase1

2004 ◽  
Vol 71 (6) ◽  
pp. 1822-1827 ◽  
Author(s):  
Soma Bandyopadhyay ◽  
Sutapa Banerjee ◽  
Alok K. Pal ◽  
Sourendra K. Goswami ◽  
Baidyanath Chakravarty ◽  
...  
Keyword(s):  
Cell Migration ◽  
Germ Cell ◽  
Primordial Germ Cell ◽  
Preliminary Evidence ◽  
Germ Cell Migration

Role of GAGA factor in drosophila primordial germ cell migration and gonad development

2016 ◽  
Vol 47 (1) ◽  
pp. 33-40
Author(s):  
N. V. Dorogova ◽  
A. S. Khrushcheva ◽  
E. V. Fedorova ◽  
A. A. Ogienko ◽  
E. M. Baricheva
Keyword(s):  
Cell Migration ◽  
Germ Cell ◽  
Primordial Germ Cell ◽  
Gonad Development ◽  
Gaga Factor ◽  
Germ Cell Migration

scholarly journals Primordial germ cell migration in the chick and mouse embryo: the role of the chemokine SDF-1/CXCL12

2004 ◽  
Vol 272 (2) ◽  
pp. 351-361 ◽  
Author(s):  
Jürg Stebler ◽  
Derek Spieler ◽  
Krasimir Slanchev ◽  
Kathleen A. Molyneaux ◽  
Ulrike Richter ◽  
...  
Keyword(s):  
Cell Migration ◽  
Germ Cell ◽  
Mouse Embryo ◽  
Primordial Germ Cell ◽  
Germ Cell Migration

zfh-1 is required for germ cell migration and gonadal mesoderm development in Drosophila

Development ◽  
1998 ◽  
Vol 125 (4) ◽  
pp. 655-666 ◽  
Author(s):  
H.T. Broihier ◽  
L.A. Moore ◽  
M. Van Doren ◽  
S. Newman ◽  
R. Lehmann
Keyword(s):  
Cell Migration ◽  
Germ Cell ◽  
Germ Cells ◽  
Ectopic Expression ◽  
Homeodomain Protein ◽  
Mesoderm Development ◽  
Visceral Mesoderm ◽  
Temporal Course ◽  
Germ Cell Migration

In Drosophila as well as many vertebrate systems, germ cells form extraembryonically and migrate into the embryo before navigating toward gonadal mesodermal cells. How the gonadal mesoderm attracts migratory germ cells is not understood in any system. We have taken a genetic approach to identify genes required for germ cell migration in Drosophila. Here we describe the role of zfh-1 in germ cell migration to the gonadal mesoderm. In zfh-1 mutant embryos, the initial association of germ cells and gonadal mesoderm is blocked. Loss of zfh-1 activity disrupts the development of two distinct mesodermal populations: the caudal visceral mesoderm and the gonadal mesoderm. We demonstrate that the caudal visceral mesoderm facilitates the migration of germ cells from the endoderm to the mesoderm. Zfh-1 is also expressed in the gonadal mesoderm throughout the development of this tissue. Ectopic expression of Zfh-1 is sufficient to induce additional gonadal mesodermal cells and to alter the temporal course of gene expression within these cells. Finally, through analysis of a tinman zfh-1 double mutant, we show that zfh-1 acts in conjunction with tinman, another homeodomain protein, in the specification of lateral mesodermal derivatives, including the gonadal mesoderm.

Primordial Germ Cell Migration

2014 ◽  
pp. 189-198
Author(s):  
Aliaksandr Dzementsei ◽  
Tomas Pieler
Keyword(s):  
Cell Migration ◽  
Germ Cell ◽  
Primordial Germ Cell ◽  
Germ Cell Migration

scholarly journals Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Yeonjoo Kim ◽  
Jiyoung Lee ◽  
Maisa Seppala ◽  
Martyn T. Cobourne ◽  
Soo-Hyun Kim
Keyword(s):  
Cell Migration ◽  
Germ Cell ◽  
Primordial Germ Cell ◽  
Hedgehog Signalling ◽  
Germ Cell Migration
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