Vesicular neurotransmitter transport and the presynaptic regulation of quantal size

1998 ◽  
Vol 8 (3) ◽  
pp. 405-412 ◽  
Author(s):  
Richard J Reimer ◽  
Edward A Fon ◽  
Robert H Edwards
Keyword(s):  
Quantal Size ◽  
Neurotransmitter Transport ◽  
Presynaptic Regulation

scholarly journals Presynaptic regulation of quantal size: K+/H+ exchange stimulates vesicular glutamate transport

2011 ◽  
Vol 14 (10) ◽  
pp. 1285-1292 ◽  
Author(s):  
Germaine Y Goh ◽  
Hai Huang ◽  
Julie Ullman ◽  
Lars Borre ◽  
Thomas S Hnasko ◽  
...  
Keyword(s):  
Glutamate Transport ◽  
Quantal Size ◽  
Presynaptic Regulation

The microtubule associated protein (MAP) tau forms a new class of triple-stranded left-hand helical fibrous protein polymer

1992 ◽  
Vol 50 (1) ◽  
pp. 540-541
Author(s):  
G. C. Ruben ◽  
K. Iqbal ◽  
I. Grundke-Iqbal ◽  
H. Wisniewski ◽  
T. L. Ciardelli ◽  
...  
Keyword(s):  
Axial Ratio ◽  
Normal Structure ◽  
Paired Helical Filaments ◽  
Left Hand ◽  
New Class ◽  
Protein Polymer ◽  
Fibrous Protein ◽  
Protein Map ◽  
Neurotransmitter Transport ◽  
Alzheimer Neurofibrillary Tangles

In neurons, the microtubule associated protein, tau, is found in the axons. Tau stabilizes the microtubules required for neurotransmitter transport to the axonal terminal. Since tau has been found in both Alzheimer neurofibrillary tangles (NFT) and in paired helical filaments (PHF), the study of tau's normal structure had to preceed TEM studies of NFT and PHF. The structure of tau was first studied by ultracentrifugation. This work suggested that it was a rod shaped molecule with an axial ratio of 20:1. More recently, paraciystals of phosphorylated and nonphosphoiylated tau have been reported. Phosphorylated tau was 90-95 nm in length and 3-6 nm in diameter where as nonphosphorylated tau was 69-75 nm in length. A shorter length of 30 nm was reported for undamaged tau indicating that it is an extremely flexible molecule. Tau was also studied in relation to microtubules, and its length was found to be 56.1±14.1 nm.

Increase in perforant path quantal size in aged F-344 rats

1991 ◽  
Vol 12 (5) ◽  
pp. 441-448 ◽  
Author(s):  
T.C. Foster ◽  
C.A. Barnes ◽  
G. Rao ◽  
B.L. McNaughton
Keyword(s):  
Perforant Path ◽  
Quantal Size
Sign in / Sign up

Export Citation Format

Share Document