O54 Myotonic-like EMG activity of the urethral sphincter in women with urinary retention and the use of botulinum toxin to treat this disorder

1990 ◽  
Vol 20 ◽  
pp. 19s
Author(s):  
Clare J. Fowler ◽  
Jalesh N. Panicker

If a young woman in complete urinary retention is investigated and all urological and neurological investigations are found to be normal, the commonest diagnosis then made is Fowler’s syndrome (FS). Described by Fowler et al. in 1987, the original syndrome comprised of complete urinary retention with the finding of a particular pattern of electromyographic (EMG) activity recorded with a concentric needle electrode from the striated urethral sphincter, in a young woman with clinical features of polycystic ovaries. Prior to that, description medical opinion was that urinary retention in young women was due to ‘hysteria’; more had been written about ‘psychogenic urinary retention in women’ than any other possible causes. Twenty-five years on, the situation now seems to be that if neither the urologist or urologist can discover an underlying abnormality, the woman may be told she has FS without any positive identification of that condition.


2002 ◽  
Vol 13 (1) ◽  
pp. 55-56 ◽  
Author(s):  
C. P. Smith ◽  
M. O’Leary ◽  
J. Erickson ◽  
G. T. Somogyi ◽  
M. B. Chancellor

1985 ◽  
Vol 4 (1) ◽  
pp. 15-21 ◽  
Author(s):  
H. Colstrup ◽  
L. Jørgensen ◽  
G. Lose ◽  
J. K. Kristensen ◽  
J. T. Andersen ◽  
...  

2009 ◽  
Vol 9 ◽  
pp. 1300-1305 ◽  
Author(s):  
Lori Dyer ◽  
Israel Franco

Although, the role of Botulinum Toxin-A in the treatment of the neurogenic and non-neurogenic neurogenic bladder is becoming more defined, this is the first review article to characterize the emerging role of Botulinum Toxin-A in the pediatric urologic population. Injection of Botulinum Toxin-A at the level of the bladder works by inhibiting uninhibited bladder contractions and, possibly, by blocking some of the sensory nerve fibers. In children with sphincter dyssynergy, injection at the level of the urethral sphincter works by inhibiting the involuntary guarding reflex and blocking dyssynergic voiding.


2001 ◽  
Vol 165 (4) ◽  
pp. 1107-1110 ◽  
Author(s):  
MICHAEL W. PHELAN ◽  
MICHAEL FRANKS ◽  
GEORGE T. SOMOGYI ◽  
TERUHIKO YOKOYAMA ◽  
MATTHEW O. FRASER ◽  
...  

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