Stereotactic Radiosurgery Plus Whole-Brain Radiation Therapy vs Stereotactic Radiosurgery Alone for Treatment of Brain Metastases: A Randomized Controlled Trial

2007 ◽  
Vol 2007 ◽  
pp. 204-205
Author(s):  
N.H. Hanna
Keyword(s):  
Randomized Controlled Trial ◽  
Radiation Therapy ◽  
Brain Metastases ◽  
Stereotactic Radiosurgery ◽  
Controlled Trial ◽  
Whole Brain Radiation Therapy ◽  
Whole Brain ◽  
Randomized Controlled ◽  
Whole Brain Radiation ◽  
Brain Radiation

scholarly journals The Rationale for Adjuvant Whole Brain Radiation Therapy with Radiosurgery in the Treatment of Single Brain Metastases

2003 ◽  
Vol 2 (2) ◽  
pp. 111-115 ◽  
Author(s):  
Roy A. Patchell ◽  
William F. Regine
Keyword(s):  
Radiation Therapy ◽  
Brain Metastases ◽  
Stereotactic Radiosurgery ◽  
Scientific Evidence ◽  
Focal Therapy ◽  
Whole Brain Radiation Therapy ◽  
Conventional Surgery ◽  
Whole Brain ◽  
Whole Brain Radiation ◽  
Brain Radiation

Randomized trials have established the efficacy of focal treatment (either stereotactic radiosurgery or conventional surgery) for single brain metastases. In the past, adjuvant whole brain radiation therapy (WBRT) was routinely given with focal therapy. Recently, the utility of adjuvant WBRT has been called into question. This paper examines the scientific evidence and the arguments, pro and con, concerning the use of adjuvant WBRT in association with stereotactic radiosurgery or conventional surgery.

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