P1.041 Factor structure of the Geriatric Depression Scale in Turkish Parkinson's disease patients

Background The relationship between hippocampal and amygdaloid volumes and depression in patients with Parkinson’s disease (PD) is a controversial issue. Purpose To investigate the correlation between the 15-item shortened version of the Geriatric Depression Scale (GDS-15) and gray matter volume in PD. Material and Methods In the present study, 46 participants with PD were scanned with 3 T magnetic resonance imaging (MRI) to obtain three-dimensional (3D) T1-weighted (T1W) images. Neurologists specializing in movement disorders performed clinical evaluations of the participants (e.g. GDS-15, Mini-Mental State Examination, PD duration, age, sex). Statistical Parametric Mapping 8 software was used for image gray matter segmentation and for a correlation analysis between gray matter volume and GDS-15 score. Results The results showed a significant negative correlation between GDS-15 score and left hippocampal volume, and between GDS-15 score and right parahippocampal gyrus volume. No significant positive correlations were found in the whole brain. Conclusion The current results provide new evidence regarding the relationship between depression in PD and hippocampal volume.

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The accuracy of diagnosis of major depression in patients with Parkinson's disease: a comparative study among the UPDRS, the geriatric depression scale and the Beck depression inventory

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x2008000200002 ◽

2008 ◽

Vol 66 (2a) ◽

pp. 152-156 ◽

Cited By ~ 38

Author(s):

Vitor Tumas ◽

Guilherme Gustavo Ricioppo Rodrigues ◽

Tarsis Leonardo Almeida Farias ◽

José Alexandre S. Crippa

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Major Depression ◽

Beck Depression Inventory ◽

Geriatric Depression Scale ◽

Depression Scale ◽

Diagnostic Value ◽

Geriatric Depression ◽

Operating Characteristics ◽

Highly Correlated

OBJECTIVE: Evaluate the accuracy of diagnosis of major depression in patients with Parkinson's disease (PD) using the UPDRS, the 15-item Geriatric Depression Scale (GDS15) and the Beck Depression Inventory (BDI). METHOD: 50 consecutive patients with PD were evaluated. The diagnosis of major depression was made according to the DSM-IV criteria. RESULTS: We found a 24% prevalence of major depression. All depression scales were highly correlated but UPDRS depression item had the lowest diagnostic value. The GDS15 had the more appropriate "receiver operating characteristics" curve. The best cut-off scores for screening depression were 17/18 for BDI and 8/9 for GDS15. We did not find any correlation between the level of depression and intensity of motor symptoms, functional capacity and duration of the disease. CONCLUSION: GDS15 is better than the BDI and the UPDRS for screening depression in PD and depression is not related to the degree of parkinsonian symptoms.

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Improved function and geriatric depression scale profile in outpatients with parkinson’s disease through the participation in Lee Silverman Voice Therapy BIG® program

Physical Medicine and Rehabilitation Research ◽

10.15761/pmrr.1000152 ◽

2017 ◽

Vol 2 (4) ◽

Author(s):

Walter K ◽

Pizzichetta K ◽

Metz J ◽

DiCarlo D ◽

Sieban A ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Geriatric Depression Scale ◽

Depression Scale ◽

Voice Therapy ◽

Geriatric Depression ◽

Improved Function ◽

Scale Profile

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Reliability and Validity of the Geriatric Depression Scale in Italian Subjects with Parkinson’s Disease

Parkinson s Disease ◽

10.1155/2018/7347859 ◽

2018 ◽

Vol 2018 ◽

pp. 1-6 ◽

Cited By ~ 15

Author(s):

Perla Massai ◽

Francesca Colalelli ◽

Julita Sansoni ◽

Donatella Valente ◽

Marco Tofani ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Internal Consistency ◽

Discriminant Validity ◽

Geriatric Depression Scale ◽

Depression Scale ◽

Reliability And Validity ◽

Geriatric Depression ◽

Retest Reliability ◽

Test Retest Reliability

Introduction. The Geriatric Depression Scale (GDS) is commonly used to assess depressive symptoms, but its psychometric properties have never been examined in Italian people with Parkinson’s disease (PD). The aim of this study was to study the reliability and validity of the Italian version of the GDS in a sample of PD patients. Methods. The GDS was administered to 74 patients with PD in order to study its internal consistency, test-retest reliability, construct, and discriminant validity. Results. The internal consistency of GDS was excellent (α = 0.903), as well as the test-retest reliability (ICC = 0.941 [95% CI: 0.886–0.970]). GDS showed a strong correlation with instruments related to the depression (ρ = 0.880) in PD (ρ = 0.712) and a weak correlation with generic measurement instruments (−0.320 < ρ <−0.217). An area under the curve of 0.892 (95% CI 0.809–0.975) indicated a moderate capability to discriminate depressed patients to nondepressed patient, with a cutoff value between 15 and 16 points that predicts depression (sensitivity = 87%; specificity = 82%). Conclusion. The GDS is a reliable and valid tool in a sample of Italian PD subjects; this scale can be used in clinical and research contexts.

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