Abstract #236: Efficacy of Fracture Risk Reduction With Risedronate is Demonstrated in Postmenopausal Women With Loss or Gain of Bone Mineral Density During Treatment

2006 ◽  
Vol 12 ◽  
pp. 37-38
Author(s):  
Andrea B. Klemes ◽  
Nelson B. Watts ◽  
Jacques P. Brown ◽  
Paul D. Miller ◽  
Steven Boonen
Keyword(s):  
Bone Mineral Density ◽  
Fracture Risk ◽  
Postmenopausal Women ◽  
Risk Reduction ◽  
Bone Mineral ◽  
Mineral Density ◽  
Fracture Risk Reduction

Bone mineral density as a surrogate biomarker for fracture risk reduction – Authors' reply

2020 ◽  
Vol 8 (11) ◽  
pp. 876
Author(s):  
Dennis M Black ◽  
Mary L Bouxsein ◽  
Douglas C Bauer ◽  
Richard Eastell
Keyword(s):  
Bone Mineral Density ◽  
Fracture Risk ◽  
Risk Reduction ◽  
Bone Mineral ◽  
Mineral Density ◽  
Fracture Risk Reduction

Bone mineral density as a surrogate biomarker for fracture risk reduction

2020 ◽  
Vol 8 (11) ◽  
pp. 875-876
Author(s):  
Josivan G Lima ◽  
Lucia H C Nóbrega ◽  
Marcel C F Santos ◽  
Breno C C Simas
Keyword(s):  
Bone Mineral Density ◽  
Fracture Risk ◽  
Risk Reduction ◽  
Bone Mineral ◽  
Mineral Density ◽  
Fracture Risk Reduction

scholarly journals Relationship Between Bone Mineral Density Changes and Fracture Risk Reduction in Patients Treated With Strontium Ranelate

2008 ◽  
Vol 63 (1) ◽  
pp. 36-37
Author(s):  
Olivier Bruyere ◽  
Christian Roux ◽  
Johann Detilleux ◽  
Daniel O. Slosman ◽  
Tim D. Spector ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Fracture Risk ◽  
Risk Reduction ◽  
Bone Mineral ◽  
Strontium Ranelate ◽  
Mineral Density ◽  
Fracture Risk Reduction

scholarly journals Comparison of Bone Mineral Density, T-Scores and Serum Zinc between Diabetic and Non Diabetic Postmenopausal Women with Osteoporosis

2015 ◽  
Vol 7 (01) ◽  
pp. 043-048 ◽  
Author(s):  
Priyanka R Siddapur ◽  
Anuradha B Patil ◽  
Varsha S Borde
Keyword(s):  
Bone Mineral Density ◽  
Fracture Risk ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Mineral Density ◽  
T Score ◽  
Increased Risk ◽  
Serum Zn ◽  
Type 2 Diabetic

ABSTRACT Context: Postmenopausal osteoporosis is a public health problem. Diabetics are at increased risk of osteoporosis-related fractures. Zinc (Zn) has a role in collagen metabolism, and its levels are altered in diabetes. Aims: The aim was to compare bone mineral density (BMD), T-score and serum Zn between diabetic and nondiabetic postmenopausal women with osteoporosis to see if they influence increased fracture risk in diabetes. Settings and Design: It is a cross-sectional study conducted at Department of Biochemistry, Jawaharlal Nehru Medical College, Belgaum. Materials and Methods: Thirty type 2 diabetic and 30 age-matched (aged 45-75 years) nondiabetic Dual energy X-ray absorptiometry (DEXA) confirmed postmenopausal osteoporotics were included from January 2011 to March 2012. Serum Zn was analyzed by atomic absorption spectrophotometry. Statistical Analysis Used: Mean and standard deviation of the parameters of the two groups were computed and compared by unpaired Student's t-test. Relationship between variables was measured by Karl Pearson's correlation co-efficient. A statistical significance is set at 5% level of significance (P < 0.05). Results: T-score was significantly higher in diabetics compared with nondiabetics(−2.84 ± 0.42 vs. −3.22 ± 0.74) P < 0.05. BMD and serum Zn of diabetics showed a significant positive correlation with body mass index (BMI). Conclusions: Type 2 diabetic postmenopausal osteoporotics have a higher T-score than the nondiabetics. High BMI in type-2 diabetes mellitus (T2DM) may contribute to high BMD and may be a protective factor against zincuria. Increased fracture risk in T2DM could be due to other factors like poor bone quality due to hyperglycemia rather than BMD. Strict glycemic control is of paramount importance.

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