Fracture Risk Assessment Tool (FRAX®) Results Calculated With and Without Bone Mineral Density Values for the Evaluation of Fracture Risk in Postmenopausal Women With Osteopenia

Abstract Dual-energy X-ray absorptiometry (DXA) and the Fracture Risk Assessment Tool are recommended tools for osteoporotic fracture risk evaluation, but are underutilized. We present a novel and fully-automated tool to identify fractures, predict bone mineral density (BMD), and evaluate fracture risk using plain pelvis and lumbar spine radiographs. The performance of this tool were evaluated in 1639 and 11908 patients with pelvis or lumbar spine radiographs and DXA, respectively. The model was well calibrated for hip and spine BMD assessments with minimal or no bias. The area under the curve and accuracy were 0.89 and 92.4% for hip osteoporosis, 0.87 and 86.8% for spine osteoporosis, 0.92 and 94.6% for high 10-year major fracture risk, and 0.92 and 92.2% for high hip fracture risk, respectively. The success rates of our automated algorithm a real-world test were 85.3% and 90.4% for hip and spine, respectively. The clinical use of this automated tool may increase the likelihood of identifying high-risk patients in previously unscreened populations.

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The role of bone mineral density in therapeutic decision-making using the Fracture Risk Assessment Tool (FRAX): a sub-study of the Taiwan OsteoPorosis Survey (TOPS)

Archives of Osteoporosis ◽

10.1007/s11657-019-0653-7 ◽

2019 ◽

Vol 14 (1) ◽

Author(s):

Jia-Feng Chen ◽

Shan-Fu Yu ◽

Chung-Yuan Hsu ◽

Wen-Chan Chiu ◽

Chih-Hsing Wu ◽

...

Keyword(s):

Bone Mineral Density ◽

Risk Assessment ◽

Decision Making ◽

Fracture Risk ◽

Assessment Tool ◽

Therapeutic Decision ◽

Mineral Density ◽

Fracture Risk Assessment Tool ◽

Therapeutic Decision Making

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Translation, cultural adaptation, and validation of the 10-year Fracture Risk Assessment Tool into Filipino

Journal of Orthopaedics Trauma and Rehabilitation ◽

10.1177/2210491720952446 ◽

2020 ◽

Vol 27 (2) ◽

pp. 198-201

Author(s):

Pauline Melisse S del Rosario ◽

Misael Jonathan A Ticman ◽

Leo Daniel D Caro

Keyword(s):

Rheumatoid Arthritis ◽

Risk Assessment ◽

Fracture Risk ◽

Assessment Tool ◽

High Energy ◽

Fracture Risk Assessment ◽

Screening Tools ◽

Risk Assessment Tool ◽

Mineral Density ◽

Fracture Risk Assessment Tool

Introduction: Screening tools for osteoporosis are relatively expensive and inaccessible to the general Filipino population. This study aims to develop a Filipino version of a validated measure, the Fracture Risk Assessment Tool (FRAX), in order to facilitate improvement of fracture prevention care in the country. Methods: The FRAX was translated and culturally adapted into a Filipino version using established forward and backward translation methods and was succeedingly tested for equivalence to the original. The final version was administered to 120 outpatients and was tested for reliability using peripheral dual-energy x-ray absorptiometry (DXA) measurements of the distal radius. Results: To be better understood and reliably answered by the Filipino population, several qualifiers were added to items such as previous fracture and rheumatoid arthritis. This was to account for the high incidence of high-energy trauma in the country and the use of the same Filipino term for rheumatoid arthritis (RA) as with other arthritides, respectively. Conclusion: The Filipino version of the FRAX appears to be an acceptable and reliable instrument, serving as a low-cost alternative to bone mineral density (BMD) and DXA scans which are generally inaccessible and unaffordable by majority of the populations.

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