scholarly journals Motor Unit Number Estimation in Neuromuscular Disease

2008 ◽  
Vol 35 (2) ◽  
pp. 153-159 ◽  
Author(s):  
Omid Rashidipour ◽  
K. Ming Chan
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Motor Unit ◽  
Neuromuscular Disease ◽  
Muscular Atrophy ◽  
Neuromuscular Diseases ◽  
Neuronal Loss ◽  
Response To Treatment ◽  
Motor Unit Number Estimation ◽  
Electrophysiological Method ◽  
Lateral Sclerosis

Motor unit number estimation (MUNE) is an electrophysiological method designed to quantify motor unit loss in target muscles of interest. Most of the techniques are noninvasive and are therefore well suited for longitudinal monitoring. In this brief review, we describe the more commonly used techniques and their applications in amyotrophic lateral sclerosis, poliomyelitis, spinal muscular atrophy and hereditary sensorimotor neuropathies. Findings in some of these studies offer important pathophysiological insights. Since conventional electrophysiologic methods are not sensible measures of motor neuronal loss, MUNE could play a potentially important role in the diagnosis, monitoring of disease progression and response to treatment in neuromuscular diseases in which motor unit loss is a major feature.

Monitoring disease progression using high-density motor unit number estimation in amyotrophic lateral sclerosis

2010 ◽  
Vol 42 (2) ◽  
pp. 239-244 ◽  
Author(s):  
Johannes P. van Dijk ◽  
Helenius J. Schelhaas ◽  
Ivo N. Van Schaik ◽  
Henny M.H.A. Janssen ◽  
Dick F. Stegeman ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Disease Progression ◽  
Motor Unit ◽  
High Density ◽  
Motor Unit Number Estimation ◽  
Lateral Sclerosis

scholarly journals Motor Unit Number Estimation in Evaluating Disease Progression in Patients with Amyotrophic Lateral Sclerosis

2010 ◽  
Vol 25 (9) ◽  
pp. 1359 ◽  
Author(s):  
Suk-Won Ahn ◽  
Su-Hyun Kim ◽  
Dong-Hoon Oh ◽  
Sung-Min Kim ◽  
Kyung Seok Park ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Disease Progression ◽  
Motor Unit ◽  
Motor Unit Number Estimation ◽  
Lateral Sclerosis

P7-10 Asymmetry of motor unit number estimation (MUNE) in patients with amyotrophic lateral sclerosis

2010 ◽  
Vol 121 ◽  
pp. S142-S143
Author(s):  
J.E. Kim ◽  
S.W. Ahn ◽  
S.Y. Park ◽  
S.M. Kim ◽  
K.S. Park ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Motor Unit ◽  
Motor Unit Number Estimation ◽  
Lateral Sclerosis
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