scholarly journals WS9.4 Non invasive ventilation as airway clearance technique compared to PEP in adult patients with cystic fibrosis

2013 ◽  
Vol 12 ◽  
pp. S18 ◽  
Author(s):  
M.C. Rodriguez Hortal ◽  
L. Hjelte
Keyword(s):  
Cystic Fibrosis ◽  
Adult Patients ◽  
Invasive Ventilation ◽  
Non Invasive ◽  
Airway Clearance ◽  
Non Invasive Ventilation ◽  
Clearance Technique

Non-invasive Ventilation as Airway Clearance Technique in Cystic Fibrosis

2016 ◽  
Vol 22 (3) ◽  
pp. e1667 ◽  
Author(s):  
Maria Cecilia Rodriguez Hortal ◽  
Malin Nygren-Bonnier ◽  
Lena Hjelte
Keyword(s):  
Cystic Fibrosis ◽  
Invasive Ventilation ◽  
Non Invasive ◽  
Airway Clearance ◽  
Non Invasive Ventilation ◽  
Clearance Technique

scholarly journals Randomised cross-over trial evaluating the short-term effects of non-invasive ventilation as an adjunct to airway clearance techniques in adults with cystic fibrosis

2019 ◽  
Vol 6 (1) ◽  
pp. e000399 ◽  
Author(s):  
Gemma Stanford ◽  
Helen Parrott ◽  
Diana Bilton ◽  
Penny Agent ◽  
Winston Banya ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Work Of Breathing ◽  
Evidence Base ◽  
Forced Expiratory Volume ◽  
Post Treatment ◽  
Invasive Ventilation ◽  
Non Invasive ◽  
Airway Clearance ◽  
Non Invasive Ventilation ◽  
Pre Treatment

IntroductionNon-invasive ventilation (NIV) is used in cystic fibrosis (CF) to support airway clearance techniques (ACTs) by augmenting tidal volumes and reducing patient effort. However, the evidence base for this is limited. We hypothesised that NIV, in addition to usual ACT, would increase sputum clearance. In addition, we investigated ease of sputum clearance (EoC), work of breathing (WoB) and NIV tolerability.MethodsAdults with CF (16+ years) at the end of hospitalisation for a pulmonary exacerbation were randomised to a cross-over trial of NIV-supported ACT or ACT alone in two consecutive days. No other changes to standard care were made. The primary outcome was the total 24-hour expectorated sputum wet weight after the intervention. Spirometry was completed pre-treatment and post-treatment. Oxygen saturations were measured pre-treatment, during treatment and post-treatment. EoC and WoB were assessed using Visual Analogue Scale.Results14 subjects completed the study (7 male, mean age 35 [SD 17] years, mean forced expiratory volume in 1 s [FEV1] 49 [20] % predicted). The difference between treatment regimens was −0.98 g sputum (95% CI −11.5 to 9.6, p=0.84) over 24 hours. During treatment oxygen saturations were significantly higher with NIV-supported ACT (mean difference 2.0, 95% CI 0.9 to 2.6, p=0.0004). No other significant differences were found in post-treatment FEV1, EoC, WoB, oxygen saturations or subject preference.ConclusionsThere was no difference in treatment effect between NIV-supported ACT and ACT alone, although the study was underpowered. Oxygen saturations were significantly higher during NIV-supported ACT, but with no effect on post-treatment saturations. NIV was well tolerated.Trial registration numberNCT01885650.

scholarly journals ePS3.01 Long-term effects of non-invasive ventilation for airway clearance in cystic fibrosis

2019 ◽  
Vol 18 ◽  
pp. S44
Author(s):  
P.F. Bogoni ◽  
A. Meschi ◽  
R. Bellini ◽  
S. Tomezzoli ◽  
M. Sanguanini ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Invasive Ventilation ◽  
Long Term Effects ◽  
Non Invasive ◽  
Airway Clearance ◽  
Non Invasive Ventilation

scholarly journals Clinical usage of non-invasive ventilation by physical therapists in cystic fibrosis centres across Australia: A cross-sectional survey study

2021 ◽  
Author(s):  
Molly Molly Foxcroft ◽  
Rebecca Chambers ◽  
Robyn Cobb ◽  
Suzanne Kuys ◽  
Kathleen A Hall
Keyword(s):  
Cystic Fibrosis ◽  
Physical Therapy ◽  
Physical Therapists ◽  
Shortness Of Breath ◽  
Invasive Ventilation ◽  
Non Invasive ◽  
Airway Clearance ◽  
Clinical Indications ◽  
Bilevel Positive Airway Pressure ◽  
Non Invasive Ventilation

BACKGROUND: This study investigated clinical usage of non-invasive ventilation during physical therapy for people with cystic fibrosis. Specific research questions were: 1. What are the clinical indications, contraindications and patient selection criteria for non-invasive ventilation use as an adjunct to physical therapy in people with cystic fibrosis? 2. Who implements non-invasive ventilation, what settings are used and how are they determined? 3. What outcome measures are used to determine the effectiveness of non-invasive ventilation as an adjunct to physical therapy and what are the main benefits and complications? METHODS: A purpose-designed survey was sent to 23 Australian cystic fibrosis centres. RESULTS: Fifteen centres (65%) responded, with 13 reporting current utilization of non-invasive ventilation to assist physical therapy. Non-invasive ventilation was most commonly (85%) used in patients with lung function <40% predicted. Physical therapy clinical indications included shortness of breath at rest (100%) and during airway clearance (100%), and fatigue during airway clearance (100%). Physical therapists were responsible for initiating non-invasive ventilation (62%), setting up (85%) and determining settings (62%). Bi-level ventilation was the only chosen ventilation mode. Benefits reported included improved ease of airway clearance (100%), reduced fatigue (92%) and decreased dyspnoea (85%). Only one complication of haemoptysis was reported. CONCLUSIONS: Non-invasive ventilation was used during physical therapy in people with cystic fibrosis who had severe disease, mostly during airway clearance to improve tolerability of treatment. Australian physical therapists initiated non-invasive ventilation when people with cystic fibrosis experienced shortness of breath or fatigue during treatment, aligning with current clinical guidelines. Clinical usage was largely consistent across centres, with numerous benefits and few complications reported. Further research is required to explore benefits of non-invasive ventilation use during physical therapy. Keywords: Cystic Fibrosis, Noninvasive Ventilation, Bilevel Positive Airway Pressure, Physical Therapy, Airway Clearance, Exercise

The development of oxygen and non-invasive ventilation pathways in an adult cystic fibrosis centre

Physiotherapy ◽  
2019 ◽  
Vol 105 ◽  
pp. e200-e201
Author(s):  
P. Moran ◽  
E. Pilkington ◽  
N. Bell ◽  
K. Bateman ◽  
E. Swingwood
Keyword(s):  
Cystic Fibrosis ◽  
Invasive Ventilation ◽  
Non Invasive ◽  
Non Invasive Ventilation ◽  
Cystic Fibrosis Centre
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