Liquid chromatographic method for the determination of rosiglitazone in human plasma

2003 ◽  
Vol 788 (1) ◽  
pp. 37-44 ◽  
Author(s):  
B.L Kolte ◽  
B.B Raut ◽  
A.A Deo ◽  
M.A Bagool ◽  
D.B Shinde
Keyword(s):  
Human Plasma ◽  
Chromatographic Method ◽  
Liquid Chromatographic Method ◽  
Liquid Chromatographic

A sensitive liquid-chromatographic method for determination of 3'-azido-3'-deoxythymidine (AZT) in plasma and urine.

1988 ◽  
Vol 34 (8) ◽  
pp. 1565-1568 ◽  
Author(s):  
M A Hedaya ◽  
R J Sawchuk
Keyword(s):  
Human Plasma ◽  
Prescription Drugs ◽  
Chromatographic Method ◽  
Internal Standard ◽  
Infectious Complications ◽  
Over The Counter ◽  
Internal Standards ◽  
Liquid Chromatographic Method ◽  
Liquid Chromatographic

Abstract We describe a liquid-chromatographic assay for AZT in human plasma and urine. This assay involves the use of two internal standards, allowing reference of AZT peaks to the appropriate internal standard, the choice depending on the range of concentrations encountered. This method is isocratic, specific, sensitive enough to allow quantification of AZT in concentrations observed clinically, and requires only 13 min of chromatographic time. We saw no interference from various over-the-counter and prescription drugs often used in treating the infectious complications of AIDS.

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