P.19.6 SERUM PEPSINOGEN I AND GASTRIN-17 LEVELS ARE PREDICTABLE OF ATROPHIC GASTRITIS IN PATIENTS WITH AUTOIMMUNE THYROIDITIS AND ANTI-GASTRIC PARIETAL CELL AUTOANTIBODIES

2012 ◽  
Vol 44 ◽  
pp. S209
Author(s):  
S. Russo ◽  
N. De Bortoli ◽  
I. Martinucci ◽  
E. Fiore ◽  
A.T. Provenzale ◽  
...  
Keyword(s):  
Atrophic Gastritis ◽  
Parietal Cell ◽  
Autoimmune Thyroiditis ◽  
Serum Pepsinogen ◽  
Gastric Parietal Cell ◽  
Pepsinogen I ◽  
Parietal Cell Autoantibodies

scholarly journals Estimate of the Prevalence of Anti-Gastric Parietal Cell Autoantibodies in Healthy Individuals Is Method Dependent

2018 ◽  
Vol 150 (4) ◽  
pp. 285-292 ◽  
Author(s):  
Marcello Bagnasco ◽  
Daniele Saverino ◽  
Francesca Pupo ◽  
Manuela Marchiano ◽  
Maria Grazia Alessio ◽  
...  
Keyword(s):  
Parietal Cell ◽  
Healthy Individuals ◽  
Gastric Parietal Cell ◽  
Parietal Cell Autoantibodies

Reassessment of Intrinsic Factor and Parietal Cell Autoantibodies in Atrophic Gastritis With Respect to Cobalamin Deficiency

2009 ◽  
Vol 104 (8) ◽  
pp. 2071-2079 ◽  
Author(s):  
Edith Lahner ◽  
Gary L Norman ◽  
Carola Severi ◽  
Susan Encabo ◽  
Zakera Shums ◽  
...  
Keyword(s):  
Atrophic Gastritis ◽  
Parietal Cell ◽  
Intrinsic Factor ◽  
Cobalamin Deficiency ◽  
Parietal Cell Autoantibodies

scholarly journals Accuracy of screening for gastric cancer using serum pepsinogen concentrations

Gut ◽  
1999 ◽  
Vol 44 (5) ◽  
pp. 693-697 ◽  
Author(s):  
F Kitahara ◽  
K Kobayashi ◽  
T Sato ◽  
Y Kojima ◽  
T Araki ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Atrophic Gastritis ◽  
Sensitivity And Specificity ◽  
Endoscopic Diagnosis ◽  
Screening Methods ◽  
Fundic Gland ◽  
Serum Pepsinogen ◽  
Pepsinogen I ◽  
Pepsinogen Ii ◽  
Receiver Operator Characteristics

BACKGROUND/AIMSThe characteristics of pepsinogen screening for gastric cancer were investigated to establish a suitable cut off point for identifying gastric cancer, using endoscopic diagnosis as the yardstick.SUBJECTS/METHODSSerum pepsinogen concentrations were measured in 5113 subjects who were also screened for gastric cancer by endoscopy. The cut off point for pepsinogen was determined using receiver operator characteristics curves.RESULTSThe most suitable cut off point was a pepsinogen I concentration of less than 70 ng/ml and a ratio of pepsinogen I to pepsinogen II of less than 3.0. Using this cut off point, the sensitivity and specificity of pepsinogen screening for gastric cancer were 84.6% and 73.5% respectively. All cases of gastric cancer in patients with severe atrophic gastritis were detected. However, two of four cases of gastric cancer in patients with mild atrophic gastritis were overlooked. In subjects with mild atrophic gastritis, when gastric cancer arises within the fundic gland region, the size of the lesion determines whether it is possible to detect cancer by serum pepsinogen screening.CONCLUSIONPepsinogen screening has many advantages, including its suitability for combination with other screening methods because it is simple and inexpensive.

Complement-fixing gastric parietal cell auto antibodies. A good marker for the identification of type a chronic atrophic gastritis

Autoimmunity ◽  
1988 ◽  
Vol 1 (4) ◽  
pp. 267-274 ◽  
Author(s):  
C. Betterle ◽  
P. A. Mazzi ◽  
B. Pedini ◽  
F. Accordi ◽  
A. Cecchetto ◽  
...  
Keyword(s):  
Atrophic Gastritis ◽  
Parietal Cell ◽  
Type A ◽  
Chronic Atrophic Gastritis ◽  
Gastric Parietal Cell ◽  
Good Marker

Ph 3 holding time corrllates with serum pepsinogen I/II ratio in patients with Helicobacter pylori-positive atrophic gastritis

1998 ◽  
Vol 114 ◽  
pp. A286 ◽  
Author(s):  
T. Shimatani ◽  
M. Inoue ◽  
Y. Horikawa ◽  
Y. Kawai ◽  
C. Tao ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Atrophic Gastritis ◽  
Holding Time ◽  
Serum Pepsinogen ◽  
Pepsinogen I
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