PP219-MON THYROID DYSFUNCTION AND CHILDHOOD OBESITY: CORRELATION BETWEEN HYPERTHYROTROPINEMIA, THYROID ECHOGRAPHY AND THE METABOLIC AND CARDIOVASCULAR RISK FACTORS

2012 ◽  
Vol 7 (1) ◽  
pp. 225
Author(s):  
A.-M. Pelin ◽  
V. Stefanescu
Open Medicine ◽  
2013 ◽  
Vol 8 (6) ◽  
pp. 742-748 ◽  
Author(s):  
Alexander Shinkov ◽  
Anna-Maria Borissova ◽  
Roussanka Kovatcheva ◽  
Jordan Vlahov ◽  
Lilia Dakovska ◽  
...  

AbstractThe aim of this study was to determine the prevalence of thyroid dysfunction and its association with cardiovascular risk factors in an adult Bulgarian population. 2402 subjects were studied, 1347 female, 20–94y (median: 48.0y) and 1055 male, 20–91y (median: 45.5y). Body weight, height, waist circumference, arterial blood pressure, TSH, FT4 and lipids were measured. Known hypothyroidism was reported by 53 subjects (2.2%) and hyperthyroidism by 20 (0.8%). New hypothyroidism was found in 98 (4.1%), [subclinical (3.2%), overt (0.9%)]. New hyperthyroidism was found in 68 (2.9%), [subclinical (2.5%), overt (0.4%)]. New diagnosis of hypothyroidism and hyperthyroidism was entered in 84% and 87% in male subjects and 60% and 65% in the females respectively. Arterial hypertension was present in 40% of the women and in 47% of the men (p<0.001) and was more prevalent in hypothyroidism. Abdominal obesity and dyslipidemia were more prevalent in males and hypothyroid subjects. Arterial hypertension depended on age, gender and lipid status but not on thyroid function. CHD history depended on thyroid function and age. Conclusion: Most cases of thyroid dysfunction were undiagnosed, especially in the males. CV risk factors were more prevalent in the males with thyroid dysfunction a major determinant of CHD, but not hypertension.


1991 ◽  
Vol 30 (6) ◽  
pp. 643-643
Author(s):  
K Zwlauer ◽  
Renate Pakosta ◽  
K Widhalm

Author(s):  
Laura M. Trandafir ◽  
Otilia E. Frasinariu ◽  
Calin Corciova ◽  
Lucian V. Boiculese ◽  
Mihaela Moscalu

2010 ◽  
Vol 362 (6) ◽  
pp. 485-493 ◽  
Author(s):  
Paul W. Franks ◽  
Robert L. Hanson ◽  
William C. Knowler ◽  
Maurice L. Sievers ◽  
Peter H. Bennett ◽  
...  

2010 ◽  
Vol 128 (1) ◽  
pp. 18-23 ◽  
Author(s):  
Rodrigo Diaz-Olmos ◽  
Antônio-Carlos Nogueira ◽  
Daniele Queirós Fucciolo Penalva ◽  
Paulo Andrade Lotufo ◽  
Isabela Martins Benseñor

CONTEXT AND OBJECTIVE: Subclinical thyroid dysfunction is very common in clinical practice and there is some evidence that it may be associated with cardiovascular disease. The aim here was to evaluate the frequencies of subclinical thyroid disease and risk factors for cardiovascular disease among women at a workplace, and to evaluate the association between subclinical thyroid disease and cardiovascular risk factors among them. DESIGN AND SETTING: Cross-sectional study on 314 women aged 40 years or over who were working at Universidade de São Paulo (USP). METHODS: All the women answered a questionnaire on sociodemographic characteristics and risk factors for cardiovascular disease and the Rose angina questionnaire. Anthropometric variables were measured and blood samples were analyzed for blood glucose, total cholesterol and fractions, high-sensitivity C-reactive protein, thyroid-stimulating hormone (TSH), free thyroxine (free-T4) and anti-thyroperoxidase antibodies (anti-TPO). RESULTS: The frequencies of subclinical hypothyroidism and hyperthyroidism were, respectively, 7.3% and 5.1%. Women with subclinical thyroid disease presented higher levels of anti-TPO than did women with normal thyroid function (P = 0.01). There were no differences in sociodemographic factors and cardiovascular risk factors according to thyroid function status, except for greater sedentarism among the women with subclinical hypothyroidism. Restricting the comparison to women with subclinical hypothyroidism (TSH > 10 mIU/l) did not change the results. CONCLUSION: In this sample of women, there was no association between poor profile of cardiovascular risk factors and presence of subclinical thyroid disease that would justify screening at the workplace.


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