scholarly journals Bacteraemia and bacteria spread into the irrigation fluid during percutaneous nephrolithotomy: a prospective study

2021 ◽  
Vol 32 ◽  
pp. S118
Author(s):  
E. De Lorenzis ◽  
C. Bebi ◽  
C. Silvani ◽  
L. Boeri ◽  
F. Ripa ◽  
...  
2021 ◽  
Vol 79 ◽  
pp. S203-S205
Author(s):  
E. De Lorenzis ◽  
C. Bebi ◽  
C. Silvani ◽  
L. Boeri ◽  
F. Ripa ◽  
...  

F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 1550 ◽  
Author(s):  
Firtantyo Adi Syahputra ◽  
Ponco Birowo ◽  
Nur Rasyid ◽  
Faisal Abdi Matondang ◽  
Endrika Noviandrini ◽  
...  

Objectives Bleeding is the most common complication of percutaneous nephrolithotomy (PCNL). Injudicious transfusion is frequently performed in current practice, even though it is not always needed. This study aimed to identify the predictive factors of blood loss in the PCNL procedure and evaluate the perioperative transfusion practice. Methods A prospective study of PCNL was randomly performed by two consultants of endo-urology at our institution. The inclusion criteria were adults with kidney pelvic stones >20 mm or stone in inferior calyx >10 mm or staghorn stone. Those with coagulopathy, under anti-coagulant treatment or open conversion were excluded. A full blood count was taken at baseline and during 12, 24, 36, 72-hours post-operatively. Factors such as stone burden, sex, body surface area, shifting of hematocrit level and amount of blood transfused were analyzed statistically using line regression to identify the predictive factors of total blood loss (TBL).   Results Eighty-five patients were enrolled in this study. Mean TBL was 560.92 ± 428.43 mL for both endo-urology surgeons. Stone burden was the most influential factor for TBL (p=0.037). Our results revealed that TBL (mL) = -153.379 + 0.229 × stone burden (mm2) + 0.203 x baseline serum hematocrit (%); thus considerably predicted the need for blood transfusion. A total of 87.1% patients did not receive perioperative transfusion, 3.5% received intra-operative transfusion, 7.1% received post-operative transfusion, 23% had both intra and post-operative transfusion, resulting in a cross-matched transfusion ratio of 7.72. Mean perioperative blood transfused was 356.00 ± 145.88 mL.


Author(s):  
E. De Lorenzis ◽  
L. Boeri ◽  
A. Gallioli ◽  
M. Fontana ◽  
S. P. Zanetti ◽  
...  

Abstract Purpose We evaluated if, during lithotripsy, bacteria may be detected in the irrigation fluid of percutaneous nephrolithotomy (PCNL) and retrograde intrarenal surgery (RIRS). The concordance between urine culture from stone fragmentation (SFUC), bladder (BUC), renal pelvic (RPUC) and stone (SC) was analyzed. We also assessed the correlation between variables and cultures and their association with systemic inflammatory response syndrome (SIRS) and of a positive SC. Methods We included 107 patients who underwent PCNL (n = 53) and RIRS (n = 54) from January 2017 to May 2018. Samples for RPUC were obtained by renal catheterization. Stone fragments and irrigation fluid sample were sent for culture. Results SFUC was positive in 17 (15.9%), BUC in 22 (20.6%), RPUC in 26 (24.3%) and SC in 30 patients (28%). The concordance between SFUC and SC was the highest among all cultures: 94.1%. SFUC and SC grew identical microorganisms in 15/17 (88.2%) patients. Out of 17 (15.9%) patients with SIRS, 8 (7.5%) had sepsis. SFUC had the highest PPV and specificity to detect positive SC and SIRS. Previous urinary tract infection, a preoperative nephrostomy, stone diameter and composition, staghorn calculi, PCNL, positive BUC, RPUC and SFUC were predictors of infected stone. Variables that indicate complex stones, complex PCNL and an infection of the upper tract were associated with SIRS. Conclusion SFUC is technically feasible, easy to retrieve and to analyze. The spectrum of SFUC potential application in clinical practice is when is not possible to perform a SC, e.g. complete dusting or during micro-PCNL.


Urolithiasis ◽  
2015 ◽  
Vol 44 (3) ◽  
pp. 263-270 ◽  
Author(s):  
Kuldeep Sharma ◽  
Satya Narayan Sankhwar ◽  
Vishwajeet Singh ◽  
Bhupendra Pal Singh ◽  
Diwakar Dalela ◽  
...  

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