An epidemiological approach to the evaluation of disease control strategies for intestinal helminth infections: an age structured model

Author(s):  
M.S. Chan ◽  
G.F. Medley ◽  
D.A.P. Bundy
Parasitology ◽  
1994 ◽  
Vol 109 (3) ◽  
pp. 389-396 ◽  
Author(s):  
M. S. Chan ◽  
H. L. Guyatt ◽  
D. A. P. Bundy ◽  
G. F. Medley

SummaryEpidemiological modelling can be a useful tool for the evaluation of parasite control strategies. An age-structured epidemiological model of intestinal helminth dynamics is developed. This model includes the explicit representation of changing worm distributions between hosts as a result of treatment, and estimates the morbidity due to heavy infections. The model is used to evaluate the effectiveness of different programmes of age-targeted community chemotherapy in reducing the amount of morbidity due to helminth infection. The magnitude of age-related heterogeneities is found to be very important in determining the results of age-targeted treatment programmes. The model was verified using field data from control programmes for Ascaris lumbricoides and Trichuris trichiura, and was found to provide accurate predictions of prevalence and mean intensities of infection during and following different control regimes.


Author(s):  
Richard Langton ◽  
James Lindholm ◽  
James Wilson ◽  
Sally Sherman

2021 ◽  
Vol 2021 ◽  
pp. 1-20
Author(s):  
Amidou Traoré ◽  
Okana S. Sougué ◽  
Yacouba Simporé ◽  
Oumar Traoré

This paper is devoted to study the null controllability properties of a nonlinear age and two-sex population dynamics structured model without spatial structure. Here, the nonlinearity and the couplage are at the birth level. In this work, we consider two cases of null controllability problem. The first problem is related to the extinction of male and female subpopulation density. The second case concerns the null controllability of male or female subpopulation individuals. In both cases, if A is the maximal age, a time interval of duration A after the extinction of males or females, one must get the total extinction of the population. Our method uses first an observability inequality related to the adjoint of an auxiliary system, a null controllability of the linear auxiliary system, and after Kakutani’s fixed-point theorem.


1998 ◽  
Vol 107 (2-3) ◽  
pp. 289-303 ◽  
Author(s):  
Micheal S Allen ◽  
Leandro E Miranda

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