A modification of the general stochastic epidemic motivated by AIDS modelling

1993 ◽  
Vol 25 (01) ◽  
pp. 39-62 ◽  
Author(s):  
Frank Ball ◽  
Philip O'neill

This paper considers a model for the spread of an epidemic in a closed, homogeneously mixing population in which new infections occur at rate βxy/(x + y), where x and y are the numbers of susceptible and infectious individuals, respectively, and β is an infection parameter. This contrasts with the standard general epidemic in which new infections occur at rate βxy. Both the deterministic and stochastic versions of the modified epidemic are analysed. The deterministic model is completely soluble. The time-dependent solution of the stochastic model is derived and the total size distribution is considered. Threshold theorems, analogous to those of Whittle (1955) and Williams (1971) for the general stochastic epidemic, are proved for the stochastic model. Comparisons are made between the modified and general epidemics. The effect of introducing variability in susceptibility into the modified epidemic is studied.

1993 ◽  
Vol 25 (1) ◽  
pp. 39-62 ◽  
Author(s):  
Frank Ball ◽  
Philip O'neill

This paper considers a model for the spread of an epidemic in a closed, homogeneously mixing population in which new infections occur at rate βxy/(x + y), where x and y are the numbers of susceptible and infectious individuals, respectively, and β is an infection parameter. This contrasts with the standard general epidemic in which new infections occur at rate βxy. Both the deterministic and stochastic versions of the modified epidemic are analysed. The deterministic model is completely soluble. The time-dependent solution of the stochastic model is derived and the total size distribution is considered. Threshold theorems, analogous to those of Whittle (1955) and Williams (1971) for the general stochastic epidemic, are proved for the stochastic model. Comparisons are made between the modified and general epidemics. The effect of introducing variability in susceptibility into the modified epidemic is studied.


2001 ◽  
Vol 38 (01) ◽  
pp. 18-35 ◽  
Author(s):  
A. N. Startsev

A generalisation of the classical general stochastic epidemic within a closed, homogeneously mixing population is considered, in which the infectious periods of infectives follow i.i.d. random variables having an arbitrary but specified distribution. The asymptotic behaviour of the total size distribution for the epidemic as the initial numbers of susceptibles and infectives tend to infinity is investigated by generalising the construction of Sellke and reducing the problem to a boundary crossing problem for sums of independent random variables.


1986 ◽  
Vol 23 (03) ◽  
pp. 832-836 ◽  
Author(s):  
Frank Ball

A simple coupling argument is used to obtain a new proof of a result of Daniels (1967) concerning the total size distribution of the general stochastic epidemic. The proof admits a straightforward generalisation to multipopulation epidemics and indicates that similar results are unlikely to be available for epidemics with non-exponential infectious periods.


1986 ◽  
Vol 23 (3) ◽  
pp. 832-836 ◽  
Author(s):  
Frank Ball

A simple coupling argument is used to obtain a new proof of a result of Daniels (1967) concerning the total size distribution of the general stochastic epidemic. The proof admits a straightforward generalisation to multipopulation epidemics and indicates that similar results are unlikely to be available for epidemics with non-exponential infectious periods.


2001 ◽  
Vol 38 (1) ◽  
pp. 18-35 ◽  
Author(s):  
A. N. Startsev

A generalisation of the classical general stochastic epidemic within a closed, homogeneously mixing population is considered, in which the infectious periods of infectives follow i.i.d. random variables having an arbitrary but specified distribution. The asymptotic behaviour of the total size distribution for the epidemic as the initial numbers of susceptibles and infectives tend to infinity is investigated by generalising the construction of Sellke and reducing the problem to a boundary crossing problem for sums of independent random variables.


1982 ◽  
Vol 14 (11) ◽  
pp. 1449-1467 ◽  
Author(s):  
B Roehner ◽  
K E Wiese

A dynamic deterministic model of urban growth is proposed, which in its most simple form yields Zipf's law for city-size distribution, and in its general form may account for distributions that deviate strongly from Zipf's law. The qualitative consequences of the model are examined, and a corresponding stochastic model is introduced, which permits, in particular, the study of zero-growth situations.


1975 ◽  
Vol 12 (3) ◽  
pp. 415-424 ◽  
Author(s):  
Richard J. Kryscio

Recently, Billard (1973) derived a solution to the forward equations of the general stochastic model. This solution contains some recursively defined constants. In this paper we solve these forward equations along each of the paths the process can follow to absorption. A convenient method of combining the solutions for the different paths results in a simplified non-recursive expression for the transition probabilities of the process.


1975 ◽  
Vol 12 (01) ◽  
pp. 29-38 ◽  
Author(s):  
L. Billard

The general epidemic model does not provide for an infective recovering and thence being susceptible to further infection in the course of the epidemic. By considering the case in which recovery can occur once, we show how the state probabilities can be found for the stochastic model. This is readily extended to allow recovery up to a finite number of times.


Biometrika ◽  
1953 ◽  
Vol 40 (1-2) ◽  
pp. 177-185 ◽  
Author(s):  
NORMAN T. J. BAILEY

1971 ◽  
Vol 3 (2) ◽  
pp. 211-214
Author(s):  
Norman T. J. Bailey ◽  
Anthony S. Thomas

We consider the usual stochastic model of a general epidemic, consisting of n + 1 homogeneously mixing individuals, assuming that initially when t = 0 there is one infective and n susceptibles (Bailey (1957)). At any time t we suppose that there are r susceptibles still uninfected, s infectives in circulation, and u individuals who have been removed (and are dead, isolated, or recovered and immune), where


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