scholarly journals Duality Between the Two-Locus Wright–Fisher Diffusion Model and the Ancestral Process with Recombination

2013 ◽  
Vol 50 (01) ◽  
pp. 256-271 ◽  
Author(s):  
Shuhei Mano

Known results on the moments of the distribution generated by the two-locus Wright–Fisher diffusion model, and the duality between the diffusion process and the ancestral process with recombination are briefly summarized. A numerical method for computing moments using a Markov chain Monte Carlo simulation and a method to compute closed-form expressions of the moments are presented. By applying the duality argument, the properties of the ancestral recombination graph are studied in terms of the moments.

2013 ◽  
Vol 50 (1) ◽  
pp. 256-271 ◽  
Author(s):  
Shuhei Mano

Known results on the moments of the distribution generated by the two-locus Wright–Fisher diffusion model, and the duality between the diffusion process and the ancestral process with recombination are briefly summarized. A numerical method for computing moments using a Markov chain Monte Carlo simulation and a method to compute closed-form expressions of the moments are presented. By applying the duality argument, the properties of the ancestral recombination graph are studied in terms of the moments.


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