Late onset Cogan's syndrome

1989 ◽  
Vol 103 (5) ◽  
pp. 512-514 ◽  
Author(s):  
H. Fidler ◽  
N. S. Jones

AbstractPrevious reports describe Cogan's syndrome occurring in young adults this case shows that it can be diagnosed in an older patient, and that prompt treatment is often successful, making it a worthwhile diagnosis to consider in patients with sudden hearing loss. The erythrocyte sedimentation rate was a useful marker for disease activity in this patient.

1981 ◽  
Vol 24 (3) ◽  
pp. 501-503 ◽  
Author(s):  
Barton F. Haynes ◽  
Anita Pikus ◽  
Muriel Kaiser-Kupfer ◽  
Anthony S. Fauci

2018 ◽  
Vol 30 ◽  
pp. 50-53
Author(s):  
José Luis Treviño González ◽  
German A. Soto-Galindo ◽  
Rafael Moreno Sales ◽  
Josefina A. Morales Del Ángel

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Ahad Azami ◽  
Nasrollah Maleki ◽  
Mohammadreza Kalantar Hormozi ◽  
Zahra Tavosi

Cogan’s syndrome (CS) is a chronic inflammatory disorder of unknown etiology that most commonly affects young adults. Clinical hallmarks are bilateral interstitial keratitis and vestibuloauditory dysfunction. Association between CS and systemic vasculitis as well as aortitis also exists. The diagnosis of CS is based upon presence of characteristic inflammatory eye disease and vestibuloauditory dysfunction. We describe classic Cogan’s syndrome in a 47-year-old female from Ardabil. The patient was admitted with headache, vertigo, nausea, vomiting, right leg claudication, musculoskeletal pains, bilateral hearing loss, and blindness for the past two months. Ophthalmologic examination revealed that visual acuity was 0.1 bilaterally. Conjunctival hyperemia, bilateral cataract, and interstitial keratitis were detected with a slit lamp examination. Pure tone audiogram (PTA) and auditory brain stem response (ABR) showed bilateral sensorineural hearing loss. The other differential diagnosis of CS was studied and ruled out. Pulse i.v. methylprednisolone and cyclophosphamide were given and were followed by oral prednisolone and cyclophosphamide. Clinical follow-up showed partial improvement.


2007 ◽  
Vol 122 (3) ◽  
pp. 310-313 ◽  
Author(s):  
G J Im ◽  
H H Jung

AbstractCogan's syndrome is a rare clinical entity that is characterised by non-syphilitic interstitial keratitis and audiovestibular symptoms. The cause of Cogan's syndrome is considered to be autoimmune disease, which is supported by the resolution of hearing loss after steroid treatment, and the association with other autoimmune diseases. The sensorineural hearing loss of Cogan's syndrome is progressive over a few months, and sudden, bilateral deafness often occurs, which may be an indication for cochlear implantation. This paper presents the case of a young woman suffering from Cogan's syndrome and sudden, bilateral deafness. With reference to this case, we describe problems regarding cochlear implantation for Cogan's syndrome and radiological findings aiding selection of cochlear implantation side.


1978 ◽  
Vol 86 (3) ◽  
pp. ORL-473-ORL-478 ◽  
Author(s):  
Thomas V. McCaffrey ◽  
Thomas J. McDonald ◽  
Lee Ann McCaffrey

This review of 29 patients with relapsing polychondritis seen at the Mayo Clinic between 1962 and 1976 emphasizes the head and neck manifestations of the disease and the role of the otolaryngologist in its diagnosis and treatment. The major clinical features included inflammation of the pinna, eye involvement, nasal cartilage involvement, laryngotracheal involvement, arthropathy, hearing loss, costal chondritis, and fever. The erythrocyte sedimentation rate was often elevated, and mild anemia was not uncommon.


2019 ◽  
Vol 15 (5) ◽  
pp. e30-e32 ◽  
Author(s):  
Iván Cabezas-Rodríguez ◽  
Anahy Brandy-García ◽  
Carlos Rodríguez-Balsera ◽  
Paloma Rozas-Reyes ◽  
Belen Fernández-Llana ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
João Queirós ◽  
Sofia Maia ◽  
Mariana Seca ◽  
António Friande ◽  
Maria Araújo ◽  
...  

Background. Cogan’s syndrome is a rare clinical entity whose etiopathology is still unknown, and the treatment strategies are not clearly defined.Case. A 23-year-old male presented with symptoms of headache, peripheral facial palsy, persistent right hearing loss and bilateral papillitis. Workup excluded all infectious, granulomatous, neoplastic, and immune causes. The diagnosis of atypical Cogan’s syndrome was established, and the patient was treated with systemic corticosteroids and later on with cyclophosphamide and methotrexate. There were improvement of visual symptoms and stabilisation of left hearing.Conclusion. Cogan’s syndrome is a very rare disease with no specific biological tests for the diagnosis. The diagnostic exams are mostly important to exclude other etiologies. The atypical ocular and audiovestibular manifestations make the diagnosis difficult, delaying the institution of appropriate therapy which may result in profound bilateral deafness.


1984 ◽  
Vol 82 (2) ◽  
pp. 198-200 ◽  
Author(s):  
Paul Froom ◽  
Shaoul Margaliot ◽  
Yeheskial Caine ◽  
Jochanan Benbassat

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