Interdigitating dendritic cell sarcoma of the parotid gland

2005 ◽  
Vol 120 (3) ◽  
pp. 244-246 ◽  
Author(s):  
M Sharma ◽  
F Ahsan ◽  
K W Ah-See ◽  
M E McKean ◽  
R Kain ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Dendritic Cell ◽  
Parotid Gland ◽  
Histopathological Examination ◽  
Single Case ◽  
Needle Aspiration ◽  
Soft Tissue Tumour ◽  
Dendritic Cell Sarcoma ◽  
Single Case Report ◽  
Tissue Tumour

Interdigitating dendritic cell sarcomas (IDCSs) are extremely uncommon tumours that arise predominantly in lymphoid tissue. We report a case of an IDCS arising in the parotid gland of a 73-year-old man. Clinically, a primary salivary gland tumour was suspected but fine needle aspiration cytology suggested a soft tissue tumour. A diagnosis of IDCS was made on histopathological examination of the resection specimen, with subsequent confirmation by electron microscopy. Given the extreme rarity of this tumour at this site, it is unlikely to be a common diagnostic problem, but the importance of multiple diagnostic modalities is emphasized. The findings of cytology, histology, immunohistochemistry and electron microscopy have not previously been described together in a single case report of this tumour.

Fine Needle Aspiration Cytology in Follicular Dendritic Cell Sarcoma

2007 ◽  
Vol 51 (4) ◽  
pp. 642-647 ◽  
Author(s):  
Yuen-Shan Fan ◽  
Wai-Kuen Ng ◽  
Alice Chan ◽  
Gavin Shueng-Wai Chan ◽  
Janice Tsang ◽  
...  
Keyword(s):  
Dendritic Cell ◽  
Fine Needle Aspiration ◽  
Follicular Dendritic Cell ◽  
Needle Aspiration ◽  
Follicular Dendritic Cell Sarcoma ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Cell Sarcoma ◽  
Dendritic Cell Sarcoma ◽  
Needle Aspiration Cytology

Cytomorphological Findings of Follicular Dendritic Cell Sarcoma on Fine-Needle Aspiration Cytology

2017 ◽  
Vol 62 (2) ◽  
pp. 145-150 ◽  
Author(s):  
Sandeep S. Ojha ◽  
Rubal Jain ◽  
Farah Meenai ◽  
Ramrao Nilkanthe ◽  
Amit Haritwal
Keyword(s):  
Dendritic Cell ◽  
Follicular Dendritic Cell ◽  
Needle Aspiration ◽  
Follicular Dendritic Cell Sarcoma ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Cell Sarcoma ◽  
Dendritic Cell Sarcoma ◽  
Follicular Dendritic ◽  
Needle Aspiration Cytology

Background: Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm arising from follicular dendritic cells of germinal centers. The most common site of origin is lymph nodes and it may mimic a variety of tumors at that location, including carcinomas and sarcomas. Diagnosis is frequently missed on cytology as there are very few case reports describing the cytological characteristics of the lesion. Even on histology, a high degree of suspicion is required for an appropriate diagnosis. Case: A 60-year-old male presented with a gradually increasing left submandibular mass that had been present for 3 months. Fine-needle aspiration cytology (FNAC) was performed, showing many clusters as well as scattered epithelioid cells with spindled to oval nuclei, nuclear pleomorphism, grooves, inclusions, and uniformly dispersed mature lymphocytes throughout the smears. The diagnosis of FDCS was suspected and was confirmed on histopathology and immunohistochemistry. Conclusion: FNAC can be a cheap, easy, and helpful tool in obtaining a diagnosis of FDCS as there are few characteristic cytological features that are better recognized than histology.

Follicular Dendritic Cell Sarcoma of the Parotid Gland Recurring 6 Times Within 12 Years

2009 ◽  
Vol 20 (6) ◽  
pp. 2171-2172 ◽  
Author(s):  
Emin Karaman ◽  
Gkioukxel Saritzali ◽  
Erkan Kilic ◽  
Nazim Korkut ◽  
Ozgun Enver
Keyword(s):  
Dendritic Cell ◽  
Parotid Gland ◽  
Follicular Dendritic Cell ◽  
Follicular Dendritic Cell Sarcoma ◽  
Cell Sarcoma ◽  
Dendritic Cell Sarcoma ◽  
Follicular Dendritic

scholarly journals A Case of Disseminated Extranodal Interdigitating Dendritic Cell Sarcoma Arising from Parotid Gland

2015 ◽  
Vol 30 (2) ◽  
pp. 163 ◽  
Author(s):  
Young Hoon Park ◽  
Shin Il Kim ◽  
Suk Jin Choi ◽  
Joo Han Lim ◽  
Hyeon Gyu Yi ◽  
...  
Keyword(s):  
Dendritic Cell ◽  
Parotid Gland ◽  
Cell Sarcoma ◽  
Dendritic Cell Sarcoma ◽  
Interdigitating Dendritic Cell Sarcoma

scholarly journals Intraneural synovial sarcoma of median nerve

2020 ◽  
pp. 275-279
Author(s):  
Sandeep Bhardwaj ◽  
Anil Kansal ◽  
Rohit Bansil ◽  
Rakesh Singh ◽  
Akangsha Sharma
Keyword(s):  
Median Nerve ◽  
Synovial Sarcoma ◽  
Histopathological Examination ◽  
Soft Tissue Tumour ◽  
Rare Tumour ◽  
Nerve Sheath Tumour ◽  
Nerve Sheath ◽  
Tissue Tumour ◽  
Dismal Prognosis ◽  
Synovial Sarcomas

Synovial sarcomas are highly aggressive soft tissue tumour with a poor and dismal prognosis. These tumours have a high propensity for distant metastasis and local recurrence.  Although originally believed to arise from synovium, these tumours have been found to occur anywhere in body [1],[2]. We report here, a case of median nerve sarcoma in a 15-year female. This is a rare tumour, which is diagnosed only after histopathological examination with only a few cases reported in the literature (Table 1). Although preoperatively tumour was thought to be a nerve sheath tumour, on histopathology analysis was found to be synovial sarcoma. Despite aggressive behaviour, wide local excision is recommended even in smaller lesions. So, the diagnosis should always be kept in differentials of nerve sheath tumour, as what may be a synovial sarcoma.

scholarly journals Surgical excision of complex lipoma from the foot: a case report 

2020 ◽  
Author(s):  
Akram Uddin ◽  
George Flanagan ◽  
Ian Reilly
Keyword(s):  
Soft Tissue ◽  
Diagnostic Imaging ◽  
Histopathological Examination ◽  
Histopathological Analysis ◽  
Soft Tissue Tumour ◽  
Foot And Ankle ◽  
Level Of Evidence ◽  
Plantar Aspect ◽  
Tissue Tumour ◽  
Patient Reported

Abstract Background: Soft tissue malignant tumours of the foot and ankle are rare. Diagnostic imaging and interventional biopsy are vital to establish the nature and grading of a suspicious tumour prior to surgical intervention. The purpose of the study is to provide an account on how a symptomatic mass to the plantar aspect of the foot warranted a referral to a sarcoma centre, highlighting the importance of having urgent access to diagnostic imaging and a pathway to refer suspected cases to specialist centres. Method: A single patient with a symptomatic soft tissue tumour of the plantar foot was referred from our service to the regional sarcoma centre. It was considered to be benign and therefore open surgical resection was performed under local anaesthesia by our team, and the lesion sent for histopathological examination. Results: Histopathological analysis identified the excised mass as a lipoma to show no atypia or necrosis and mature adipose tissue with fibrous bands. At 2 years postoperatively there was no recurrence and the patient presented an asymptomatic foot. Favourable patient reported outcomes measures were observed. Conclusion: United Kingdom (UK) Guidelines suggest that all soft tissue masses of suspicious nature, greater than 50mm, deep seated irrespective of size, or fast growing should be referred to a sarcoma unit prior to surgical management. European guidance identifies a threshold of 15mm for a mass in the foot. Patients presenting with red flag symptoms irrespective of size of mass should be referred to a sarcoma centre. Advanced imaging and multidisciplinary input to enable appropriate surgical planning is recommended for these soft tissue tumours that present to the foot and ankle surgeon.Level of evidence: V case study.

scholarly journals A large malignant oncocytoma of parotid gland: a case report

2020 ◽  
Vol 6 (12) ◽  
pp. 2310
Author(s):  
Nidhi S. Mohan ◽  
Sunita S. Vernekar ◽  
Mohammed M. Abus Samee ◽  
Manjunath D.
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Fine Needle Aspiration ◽  
Facial Palsy ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

<p class="abstract">Malignant oncocytoma is an extremely rare neoplasm of the salivary gland accounting for 0.5% of epithelial salivary gland malignancies and 0.18% of epithelial salivary gland tumors. We report a case of malignant oncocytoma of left parotid gland in a 61-year old female patient. Patient presented with a 6-year history of painless swelling in the left parotid region. Fine needle aspiration cytology of the swelling was suggestive of pleomorphic adenoma. A computed tomography scan performed did not reveal any features suggestive of malignancy. Patient underwent left superficial parotidectomy. However, histopathological examination of the specimen turned out to be malignant oncocytoma. Malignant oncocytoma of salivary glands have rare incidence and may have similar morphologic features with other neoplasms. Despite the tumor being large and malignant in this case, there was no facial palsy preoperatively. As histopathology is often diagnostic, the possibility of malignancy always must be kept in mind preoperatively even when there is no facial palsy or fine needle aspiration cytology not showing up malignancy.</p>

The incidence and relevance of Non-Fatty components in trunk and extremity lipomatous soft tissue masses

2021 ◽  
pp. 20201403
Author(s):  
Rupert Berkeley ◽  
Odinakachukwu Okereke ◽  
Karan Malhotra ◽  
Asif Saifuddin
Keyword(s):  
Soft Tissue ◽  
Spindle Cell ◽  
Single Case ◽  
Myxoid Liposarcoma ◽  
Histological Diagnosis ◽  
Soft Tissue Tumour ◽  
Spindle Cell Lipoma ◽  
Tissue Tumour ◽  
Soft Tissue Masses ◽  
Final Histological Diagnosis

Objectives: To determine the incidence and diagnostic relevance of non-fatty ‘solid appearing’ components within lipomatous tumours of the trunk and extremity. Methods and materials: Retrospective review of patients referred to a specialist musculoskeletal oncology service over a 12 month period with a lipomatous trunk or extremity soft tissue tumour. The presence and morphology (solitary/multifocal; homogeneous/heterogeneous; well-defined/poorly-defined) of non-fatty components was recorded based on MRI, and compared with the final histological diagnosis. Results: 213 patients with 217 lipomatous tumours were included, 119 (55.9%) males and 94 (44.1%) females with mean age of 54.6 years (range 7–93 years). Seventy-seven (35.5%) lesions arose superficial to the fascia and 139 (64.1%) deep, while a single case involved both compartments. Mean maximal tumour dimension was 94.9 mm (range 12–288 mm). Non-fatty ‘solid appearing’ components were identified in 28 (12.9%) cases, of which eight were solitary and 20 were multifocal, six had homogeneous SI and 22 had heterogeneous SI, and eight had well-defined margins while 20 had poorly-defined margins. Histological diagnosis was available in 20 of the tumours containing non-fatty components, 16 of which were benign, two intermediate grade and two malignant (a dedifferentiated liposarcoma and a myxoid liposarcoma). The commonest diagnosis was spindle cell lipoma, which accounted for 10 of 20 (50%) cases with confirmed histology. Conclusions: Non-fatty components are identified in ~13% of trunk and extremity lipomatous tumours. The majority of such lesions are benign lipoma variants, most commonly spindle cell lipoma. Advances in knowledge: Solid non-fatty components are identified in approximately 13% of lipomatous tumours referred to a specialist sarcoma service. Despite the concern that these may represent dedifferentiated liposarcomas, high-grade tumours were seen in only two cases, the commonest diagnosis being a spindle cell lipoma.

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