Postural Sway and Effect of Levodopa in Early Parkinson's Disease

Objective:To characterize postural stability control and levodopa responsiveness in early Parkinson's disease (PD).Methods:Postural sway was studied during quiet stance in ten patients within six years of PD onset, both before (OFF) and after (ON) regular oral levodopa dosing. Postural sway was recorded using a force platform during 30 sec with eyes open, and six dependent variables were examined.Results:Mild baseline subclinical changes in postural sway were recorded in our patients. Clear benefit was observed in five out of six characteristics (mean sway, transversal sway, sagittal sway, sway intensity, and sway area) in the ON condition.Conclusion:Postural control mechanisms are affected early in PD and modulated by dopamine.

Download Full-text

Characteristics of Standing Postural Control in Women under Additional Load

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17020490 ◽

2020 ◽

Vol 17 (2) ◽

pp. 490

Author(s):

Bożena Wojciechowska-Maszkowska ◽

Dorota Borzucka

Keyword(s):

Postural Control ◽

Postural Stability ◽

Postural Sway ◽

Center Of Pressure ◽

Stability Control ◽

Standing Posture ◽

Additional Load ◽

Eyes Open ◽

Heavy Loads ◽

Load Conditions

The aim of this study was to evaluate the effect of additional load on postural-stability control in young women. To evaluate postural control in the 34 women in this study (mean age, 20.8 years), we measured postural sway (center of pressure, COP) in a neutral stance (with eyes open) in three trials of 30 s each. Three load conditions were used in the study: 0, 14, and 30 kg. In analysis, we used three COP parameters, variability (linear), mean sway velocity (linear), and entropy (nonlinear). Results suggested that a considerable load on a young woman’s body (approximately 48% of body weight) had significant influence on stability. Specifically, heavy loads triggered random movements, increased the dynamics of postural-stability control, and required more attention to control standing posture. The results of our study indicate that inferior postural control mainly results from insufficient experience in lifting such a load.

Download Full-text

249 RELATIONSHIP BETWEEN EXCESSIVE POSTURAL SWAY IN DYNAMIC CONDITION AND POSTURAL STABILITY IN QUIET STANDING IN PARKINSON'S DISEASE

Parkinsonism & Related Disorders ◽

10.1016/s1353-8020(10)70250-9 ◽

2010 ◽

Vol 16 ◽

pp. S71-S72

Author(s):

J. Nantel ◽

H. Brontë-Stewart

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Postural Stability ◽

Postural Sway ◽

Dynamic Condition ◽

Quiet Standing

Download Full-text

Postural Sway and Perception of the Upright Stance Stability Borders

Perception ◽

10.1068/p221333 ◽

1993 ◽

Vol 22 (11) ◽

pp. 1333-1341 ◽

Cited By ~ 28

Author(s):

Janusz W Blaszczyk ◽

Paul D Hansen ◽

Deborah L Lowe

Keyword(s):

Postural Stability ◽

Postural Sway ◽

Age Groups ◽

The Elderly ◽

Stability Control ◽

Center Of Gravity ◽

Elderly Subjects ◽

Experimental Conditions ◽

Eyes Closed ◽

Eyes Open

Decline in the perception of the borders of postural stability due to increase in sway was evaluated in young and elderly subjects. Ranges of lateral and anteroposterior postural sway were measured in eleven young and eleven elderly subjects during maximum voluntary excursions of center of gravity while leaning forward, backward, left, and right. In both age groups, displacement of the center of gravity out of the reference position resulted in increases in the range of sway in the plane corresponding to the direction of lean. Young subjects who further displaced their center of gravity within the base of support also exhibited significantly elevated anteroposterior sway range while leaning forward and backward, both in eyes-closed and in eyes-open experimental conditions. The elderly subjects, however, showed greater mediolateral oscillation of center of gravity while leaning forward with their eyes open. No significant intergroup differences in the anteroposterior sway range during leans in the mediolateral plane were found. However, a greater mediolateral component of sway range at lateral borders of stability was observed in the young adults. Analysis of signal-to-noise ratios indicated a greater decline in stability control in the elderly, due to impairment of perception of postural stability borders.

Download Full-text