Does tip-of-the-tongue for proper names discriminate amnestic mild cognitive impairment?

2012 ◽  
Vol 25 (4) ◽  
pp. 627-634 ◽  
Author(s):  
Onésimo Juncos-Rabadán ◽  
David Facal ◽  
Cristina Lojo-Seoane ◽  
Arturo X. Pereiro
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Verbal Fluency ◽  
Multivariate Regression ◽  
Proper Names ◽  
Naming Task ◽  
Amnestic Mild Cognitive Impairment ◽  
Regression Analyses ◽  
Tip Of The Tongue ◽  
Normal Controls

ABSTRACTBackground: Difficulty in retrieving people's names is very common in the early stages of Alzheimer's disease and mild cognitive impairment. Such difficulty is often observed as the tip-of-the-tongue (TOT) phenomenon. The main aim of this study was to explore whether a famous people's naming task that elicited the TOT state can be used to discriminate between amnestic mild cognitive impairment (aMCI) patients and normal controls.Methods: Eighty-four patients with aMCI and 106 normal controls aged over 50 years performed a task involving naming 50 famous people shown in pictures. Univariate and multivariate regression analyses were used to study the relationships between aMCI and semantic and phonological measures in the TOT paradigm.Results: Univariate regression analyses revealed that all TOT measures significantly predicted aMCI. Multivariate analysis of all these measures correctly classified 70% of controls (specificity) and 71.6% of aMCI patients (sensitivity), with an AUC (area under curve ROC) value of 0.74, but only the phonological measure remained significant. This classification value was similar to that obtained with the Semantic verbal fluency test.Conclusions: TOTs for proper names may effectively discriminate aMCI patients from normal controls through measures that represent one of the naming processes affected, that is, phonological access.

Tip-of-the-tongue for proper names in non-amnestic mild cognitive impairment

2013 ◽  
Vol 26 (3) ◽  
pp. 409-420 ◽  
Author(s):  
Onésimo Juncos-Rabadán ◽  
David Facal ◽  
Cristina Lojo-Seoane ◽  
Arturo X. Pereiro
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Proper Names ◽  
Amnestic Mild Cognitive Impairment ◽  
Tip Of The Tongue

Tip-of-the-tongue for proper names in mild cognitive impairment. Semantic or post-semantic impairments?

2011 ◽  
Vol 24 (6) ◽  
pp. 636-651 ◽  
Author(s):  
Onésimo Juncos-Rabadán ◽  
Nelly Rodríguez ◽  
David Facal ◽  
José Cuba ◽  
Arturo X. Pereiro
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Proper Names ◽  
Tip Of The Tongue ◽  
Semantic Impairments

scholarly journals Verbal fluency in categories of common and proper names in the phase of mild cognitive impairment in the course of Parkinson’s disease

1970 ◽  
Author(s):  
Renata Gliwa
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Executive Functions ◽  
Verbal Fluency ◽  
Proper Names ◽  
Test Group ◽  
Progressive Decrease ◽  
Test Result

Renata Gliwa, Verbal fluency in categories of common and proper names in the phase of mild cognitive impairment in the course of Parkinson’s disease. Interdisciplinary Contexts of Special Pedagogy, no. 27, Poznań 2019. Pp. 249–272. Adam Mickiewicz University Press. ISSN 2300-391X. e-ISSN 2658-283X. DOI: https://doi.org/10.14746/ikps.2019.27.12 The article is devoted to consideration of verbal fluency in MCI-PD. The VF test allows for the detection of dysfunctions within linguistic processes, semantic memory and dysfunctions of executive functions already in the early stages of Parkinson’sdisease. The article compares the results of verbal fluency tests in selected categories of proper names and common names, and assesses the effect of the MCIPD stage on the test result. The comparison of the test group results with various degrees of MCI indicates a progressive decrease in verbal fluency. The experiment showed different profiles of the verbal task in terms of common and proper names.

scholarly journals P2-030: 3-D mapping of verbal fluency performance in amnestic mild cognitive impairment and Alzheimer's disease

2009 ◽  
Vol 5 (4S_Part_9) ◽  
pp. P270-P270
Author(s):  
Tao Li ◽  
Mei-Yan Zhang ◽  
Jing Liao ◽  
Daniel Chang ◽  
Huishu Yuan ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Verbal Fluency ◽  
Amnestic Mild Cognitive Impairment

scholarly journals Distinct Subgroups of Amnestic Mild Cognitive Impairment as Identified by Soft Independent Modeling of Class Analogy

2019 ◽  
Author(s):  
Sookjaroen Tangwongchai ◽  
Itthipol Tawankanjanachot ◽  
Chavit Tunvirachaisakul ◽  
Thitiporn Supasitthumrong ◽  
Solaphat Hemrungrojn ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Neuropsychological Tests ◽  
Diagnostic Category ◽  
Principal Component ◽  
Amnestic Mild Cognitive Impairment ◽  
Cognitive Profile ◽  
Support Vector ◽  
Patients At Risk ◽  
Normal Controls

Amnestic mild cognitive impairment (aMCI) is a condition characterized by mild deficits in episodic and semantic memory and learning. The conversion rate of aMCI to Alzheimer disease (AD) is significantly higher in aMCI than in the general population. The aim of this study is to examine whether aMCI is a valid diagnostic category or whether aMCI comprises different subgroups based on cognitive functions. We recruited 60 aMCI patients, 60 with AD and 61 healthy controls who completed neuropsychological tests of the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD-NP) and biomarkers including serum anion gap (AGAP). Principal component analysis, support vector machine and Soft Independent Modeling of Class Analogy (SIMCA) showed that AD patients and controls were highly significantly discrimanted from each other, while patients with aMCI overlap considerably with normal controls. SIMCA showed that 68.3% of the aMCI patients were assigned to the control class (named: aMCI-HC), 15% to AD (aMCI-AD), while 16.6% did not belong to either class (aMCI-strangers). aMCI-HC subjects showed sings of very mild cognitive decline and impaired recall. aMCI-strangers showed signs of mild cognitive impairment with impaired fluency and naming. aMCI-AD cases showed a cognitive profile reminiscent of AD an increased AGAP levels. In conclusion, our SIMCA model may classify subjects afforded a clinical diagnosis of aMCI according to Petersen’s criteria into three clinically relevant subgroups and help in the early detection of AD by identifying aMCI patients at risk to develop AD and those that have an AD prodrome.

scholarly journals Category verbal fluency performance may be impaired in amnestic mild cognitive impairment

2007 ◽  
Vol 1 (2) ◽  
pp. 161-165 ◽  
Author(s):  
Márcio Luiz Figueredo Balthazar ◽  
Fernando Cendes ◽  
Benito Pereira Damasceno
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Verbal Fluency ◽  
Mood State ◽  
Digit Span ◽  
Statistical Significance ◽  
Verbal Learning ◽  
Poor Performance ◽  
Amnestic Mild Cognitive Impairment ◽  
Significance Level

Abstract To study category verbal fluency (VF) for animals in patients with amnestic mild cognitive impairment (aMCI), mild Alzheimer disease (AD) and normal controls. Method: Fifteen mild AD, 15 aMCI, and 15 normal control subjects were included. Diagnosis of AD was based on DSM-IV and NINCDS-ADRDA criteria, while aMCI was based on the criteria of the International Working Group on Mild Cognitive Impairment, using CDR 0.5 for aMCI and CDR 1 for mild AD. All subjects underwent testing of category VF for animals, lexical semantic function (Boston Naming-BNT, CAMCOG Similarities item), WAIS-R forward and backward digit span, Rey Auditory Verbal Learning (RAVLT), Mini-Mental Status Examination (MMSE), and other task relevant functions such as visual perception, attention, and mood state (with Cornell Scale for Depression in Dementia). Data analysis used ANOVA and a post-hoc Tukey test for intergroup comparisons, and Pearson's coefficient for correlations of memory and FV tests with other task relevant functions (statistical significance level was p<0.05). Results: aMCI patients had lower performance than controls on category VF for animals and on the backward digit span subtest of WAIS-R but higher scores compared with mild AD patients. Mild AD patients scored significantly worse than aMCI and controls across all tests. Conclusion: aMCI patients may have poor performance in some non-memory tests, specifically category VF for animals in our study, where this could be attributable to the influence of working memory.

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