Appropriate use of a beta-blocker in paediatric coronary CT angiography

2018 ◽  
Vol 28 (10) ◽  
pp. 1148-1153 ◽  
Author(s):  
Hirofumi Watanabe ◽  
Hiroshi Kamiyama ◽  
Masataka Kato ◽  
Akiko Komori ◽  
Yuriko Abe ◽  
...  

AbstractBackgroundThere is no standard dose or protocol for beta-blocker administration as preconditioning in children undergoing coronary CT angiography.MethodsA total of 63 consecutive patients, with a mean age of 10.0±3.1 years, who underwent coronary CT angiography to assess possible coronary complications were enrolled in a single-centre, retrospective study. All patients were given an oral beta-blocker 1 hour before coronary CT angiography. Additional oral beta-blocker or intravenous beta-blocker was given to those with a high heart rate. We compared image quality, radiation exposure, and adverse events among the patients without additional beta-blocker, with additional oral beta-blocker, and with additional intravenous beta-blocker.ResultsThere were no significant differences in image quality or radiation exposure among the groups. The heart rate just before scanning was significantly correlated with image quality (p<0.001, r=−0.533) but was not correlated with radiation exposure (p=0.45, r=0.096). There were no adverse events related to any allergic reaction, thereby showing the effectiveness of the beta-blocker.ConclusionInitial oral beta-blocker administration (0.8 mg/kg/dose) should be administered to all children undergoing coronary CT angiography. Additional intravenous beta-blocker should be given to those with poor heart rate control to improve image quality without increasing radiation exposure or allowing adverse events.

Radiology ◽  
2008 ◽  
Vol 248 (3) ◽  
pp. 792-798 ◽  
Author(s):  
Annick C. Weustink ◽  
Nico R. Mollet ◽  
Francesca Pugliese ◽  
Willem B. Meijboom ◽  
Koen Nieman ◽  
...  

2010 ◽  
Vol 51 (8) ◽  
pp. 903-909 ◽  
Author(s):  
Jonaz Ripsweden ◽  
Torkel B. Brismar ◽  
Jon Holm ◽  
Annika Melinder ◽  
Habib Mir-Akbari ◽  
...  

2010 ◽  
Vol 3 (11) ◽  
pp. 1113-1123 ◽  
Author(s):  
Jörg Hausleiter ◽  
Stefan Martinoff ◽  
Martin Hadamitzky ◽  
Eugenio Martuscelli ◽  
Iris Pschierer ◽  
...  

2019 ◽  
Vol 26 (11) ◽  
pp. 1544-1549 ◽  
Author(s):  
Saima Mushtaq ◽  
Edoardo Conte ◽  
Eleonora Melotti ◽  
Daniele Andreini

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