scholarly journals FDG-PET/CT and MR imaging for target volume delineation in rectal cancer radiotherapy treatment planning: a systematic review

2021 ◽  
pp. 1-11
Author(s):  
Elizabeth E. Olanloye ◽  
Aarthi Ramlaul ◽  
Atara I. Ntekim ◽  
Segun S. Adeyemi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Rectal Cancer ◽  
Magnetic Resonance ◽  
Fdg Pet ◽  
Target Volume ◽  
Resonance Imaging ◽  
Target Volume Delineation ◽  
Volume Delineation ◽  
Pet Ct ◽  
Fdg Pet Ct

Abstract Aim: The aim of this systematic review was to synthesise and summarise evidence surrounding the clinical use of fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT) and magnetic resonance imaging (MRI) for target volume delineation (TVD) in rectal cancer radiotherapy planning. Methods: PubMed, EMBASE, Cochrane library, CINAHL, Web of Science and Scopus databases and other sources were systematically queried using keywords and relevant synonyms. Eligible full-text studies were assessed for methodological quality using the QUADAS-2 tool. Results: Eight of the 1448 studies identified met the inclusion criteria. Findings showed that MRI significantly delineate larger tumour volumes (TVs) than FDG-PET/CT while diffusion-weighted magnetic resonance imaging (DW-MRI) defined smaller gross tumour volumes (GTVs) compared to T2 weighted-Magnetic Resonance Image. CT-based GTVs were found to be larger compared to FDG-PET/CT. FDG-PET/CT also identified new lesions in 15–17% patients and TVs extending outside the routinely used clinical standard CT TV in 29–83% patients. Between observers, delineated volumes were similar and consistent between MRI sequences, whereas interobserver agreement was significantly improved with FDG-PET/CT than CT. Conclusion: FDG-PET/CT and DW-MRI appear to delineate smaller rectal TVs and show improved interobserver variability. Overall, this study provides valuable insights into the amount of attention in the research literature that has been paid to imaging for TVD in rectal cancer.

FDG-PET/CT Imaging for Staging and Target Volume Delineation in Preoperative Conformal Radiotherapy of Rectal Cancer

2008 ◽  
Vol 70 (5) ◽  
pp. 1423-1426 ◽  
Author(s):  
Maria Chiara Bassi ◽  
Lucia Turri ◽  
Gianmauro Sacchetti ◽  
Gianfranco Loi ◽  
Barbara Cannillo ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Fdg Pet ◽  
Conformal Radiotherapy ◽  
Target Volume ◽  
Ct Imaging ◽  
Target Volume Delineation ◽  
Volume Delineation ◽  
Pet Ct ◽  
Fdg Pet Ct

scholarly journals Whole-body diffusion-weighted magnetic resonance imaging versus FDG-PET/CT for initial lymphoma staging: systematic review on diagnostic test accuracy studies

2015 ◽  
Vol 133 (2) ◽  
pp. 141-150 ◽  
Author(s):  
Rodrigo Regacini ◽  
Andrea Puchnick ◽  
David Carlos Shigueoka ◽  
Wagner Iared ◽  
Henrique Manoel Lederman
Keyword(s):  
Magnetic Resonance Imaging ◽  
Systematic Review ◽  
Magnetic Resonance ◽  
Diagnostic Test ◽  
Fdg Pet ◽  
Whole Body ◽  
Test Accuracy ◽  
Resonance Imaging ◽  
Pet Ct ◽  
Fdg Pet Ct

CONTEXT AND OBJECTIVE: Positron emission tomography with [18]F-fluoro-2-deoxyglucose (FDG-PET/CT) has been advocated as the method of choice for lymphoma staging, since it enables whole-body analysis with high sensitivity for detection of affected areas and because it combines capacities for anatomical and functional assessment. With technological advances, magnetic resonance imaging (MRI) has emerged as an alternative to FDG-PET/CT. This systematic review with meta-analysis aimed to compare whole-body diffusion-weighted MRI (WB-MRI) with FDG-PET/CT for lymphoma staging. DESIGN AND SETTING: Systematic review on diagnostic test accuracy studies conducted at a public university. METHODS: The Medline, Scopus, Embase and Lilacs databases were searched for studies published up to September 2013 that compared WB-MRI and FDG-PET/CT for lymphoma staging. The reference lists of included studies were checked for any relevant additional citations. RESULTS: Six studies that evaluated the initial lymphoma staging in 116 patients were included. WB-MRI and FDG-PET/CT agreed in 90.5% of the cases (κ = 0.871; P < 0.0001). In most of the studies, when there was disagreement between the methods, WB-MRI overstaged in relation to FDG-PET/CT. The sensitivity of WB-MRI and FDG-PET/CT, in comparison with the clinical-radiological standard, ranged from 59 to 100% and from 63 to 100% respectively. CONCLUSION: WB-MRI is a highly sensitive method for initial lymphoma staging. It has excellent agreement with FDG-PET/CT and is a great alternative for managing lymphoma patients, without using ionizing radiation or an intravenous contrast agent.

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