Effect of Trypanosoma brucei infection on the salivary gland secretions of the tsetse Glossina morsitans morsitans (Westwood)

1982 ◽  
Vol 3 (01) ◽  
pp. 35-38
Author(s):  
N. Y. Patel ◽  
L. H. Otieno ◽  
T. K. Golder
Keyword(s):  
Salivary Gland ◽  
Trypanosoma Brucei ◽  
Glossina Morsitans Morsitans ◽  
Glossina Morsitans

Trypanosome infections and survival in tsetse

Parasitology ◽  
1998 ◽  
Vol 116 (S1) ◽  
pp. S23-S28 ◽  
Author(s):  
I. Maudlin ◽  
S. C. Welburn ◽  
P. J. M. Milligan
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Trypanosoma Brucei ◽  
Glossina Morsitans Morsitans ◽  
Trypanosoma Congolense ◽  
Vectorial Capacity ◽  
Trypanosome Infection ◽  
Trypanosoma Brucei Rhodesiense ◽  
Glossina Morsitans ◽  
Differential Effects

SummaryThe effect of trypanosome infection on vector survival was observed in a line of Glossina morsitans morsitans selected for susceptibility to trypanosome infection. The differential effects of midgut and salivary gland infections on survival were examined by exposing flies to infection with either Trypanosoma congolense which colonizes midgut and mouthparts or Trypanosoma brucei rhodesiense which colonizes midgut and salivary glands. A comparison of the survival distributions of uninfected flies with those exposed to infection showed that salivary gland infection significantly reduces tsetse survival; midgut infection had little or no effect on the survival of tsetse. The significance of these findings is discussed in relation to the vectorial capacity of wild flies.

Identification of major soluble salivary gland proteins in teneral Glossina morsitans morsitans

2002 ◽  
Vol 32 (9) ◽  
pp. 1045-1053 ◽  
Author(s):  
J.D. Haddow ◽  
B. Poulis ◽  
L.R. Haines ◽  
R.H. Gooding ◽  
S. Aksoy ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Glossina Morsitans Morsitans ◽  
Glossina Morsitans

Infection of post-teneral tsetse flies (Glossina morsitans morsitans and Glossina morsitans centralis) with Trypanosoma brucei brucei

1988 ◽  
Vol 66 (6) ◽  
pp. 1289-1292 ◽  
Author(s):  
R. H. Gooding
Keyword(s):  
Trypanosoma Brucei ◽  
Significant Proportion ◽  
Glossina Morsitans Morsitans ◽  
Tsetse Flies ◽  
Glossina Morsitans ◽  
Trypanosoma Brucei Brucei ◽  
Male And Female ◽  
Glossina Morsitans Centralis

A significant proportion of post-teneral male Glossina morsitans morsitans Westwood and post-teneral male and female Glossina morsitans centralis Machado develop mature infections of Trypanosoma brucei brucei Plimmer and Bradford without being starved before feeding upon infected rabbits.

Effects of Tsetse (Glossina morsitans morsitans Westw.) (Diptera: Glossinidae) Salivary Gland Homogenate on Coagulation and Fibrinolysis

1979 ◽  
Vol 42 (02) ◽  
pp. 743-751 ◽  
Author(s):  
Kenneth R Parker ◽  
Michael J Mant
Keyword(s):  
Molecular Weight ◽  
Salivary Gland ◽  
Anticoagulant Activity ◽  
Glossina Morsitans Morsitans ◽  
Glossina Morsitans ◽  
Antithrombotic Agent ◽  
Protamine Sulphate ◽  
Esterolytic Activity ◽  
And Storage

SummaryThe saliva of the tsetse, Glossina morsitans morsitans Westwood, has antithrombin anticoagulant activity and inhibits thrombin’s esterolytic activity. It has no other detectable anticoagulant properties. The anticoagulant elutes in a single peak on Sephadex fraction, is immediately acting, heat and storage stable, and has a molecular weight of 11-13,000. Unlike heparin it is not neutralized by protamine sulphate or toluidine blue and does not require the co-factor, antithrombin III, for optimal anticoagulant activity. It has similar properties to hirudin, but does not elute with a protein peak upon Sephadex fractionation and has a slightly different molecular weight. Salivary gland homogenates contained neither a plasminogen activator nor fibrinolytic activity. The sera of rabbits used to maintain tsetses, which contained precipitating antibodies against saliva, did not neutralize the salivary anticoagulant in vitro. The properties of this anticoagulant suggest that it might be a potentially useful antithrombotic agent in man.

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