PDT-Enhanced Ferroptosis by a Polymer Nanoparticle with pH-Activated Singlet Oxygen Generation and Superb Biocompatibility for Cancer Therapy

2021 ◽  
Author(s):  
Jing Li ◽  
Junhua Li ◽  
Yuji Pu ◽  
Sai Li ◽  
Wenxia Gao ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Singlet Oxygen ◽  
Oxygen Generation ◽  
Polymer Nanoparticle ◽  
Singlet Oxygen Generation

Biodegradable Nano-photosensitizer with Photoactivatable Singlet Oxygen Generation for Synergistic Phototherapy

2021 ◽  
Author(s):  
Jiaxin Shen ◽  
Dandan Chen ◽  
Ye Liu ◽  
Guoyang Gao ◽  
Zhihe Liu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Singlet Oxygen ◽  
Near Infrared ◽  
Promising Method ◽  
Normal Cells ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Nir Light

Photodynamic therapy (PDT) is a promising method for cancer therapy and also may initiate unexpected damages to normal cells and tissues. Herein, we developed a near-infrared (NIR) light-activatable nanophotosensitizer, which...

Amplified Singlet Oxygen Generation in Semiconductor Polymer Dots for Photodynamic Cancer Therapy

2015 ◽  
Vol 8 (6) ◽  
pp. 3624-3634 ◽  
Author(s):  
Shouying Li ◽  
Kaiwen Chang ◽  
Kai Sun ◽  
Ying Tang ◽  
Ni Cui ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Singlet Oxygen ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Polymer Dots ◽  
Photodynamic Cancer Therapy

scholarly journals Activatable Singlet Oxygen Generation from Lipid Hydroperoxide Nanoparticles for Cancer Therapy

2017 ◽  
Vol 129 (23) ◽  
pp. 6592-6596 ◽  
Author(s):  
Zijian Zhou ◽  
Jibin Song ◽  
Rui Tian ◽  
Zhen Yang ◽  
Guocan Yu ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Singlet Oxygen ◽  
Lipid Hydroperoxide ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation

scholarly journals Activatable Singlet Oxygen Generation from Lipid Hydroperoxide Nanoparticles for Cancer Therapy

2017 ◽  
Vol 56 (23) ◽  
pp. 6492-6496 ◽  
Author(s):  
Zijian Zhou ◽  
Jibin Song ◽  
Rui Tian ◽  
Zhen Yang ◽  
Guocan Yu ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Singlet Oxygen ◽  
Lipid Hydroperoxide ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation

Design of Novel Photosensitizers and Controlled Singlet Oxygen Generation for Photodynamic Therapy

2021 ◽  
Author(s):  
Esra Tanrıverdi Eçik ◽  
Onur BULUT ◽  
Hasan Hüseyin Kazan ◽  
Elif Şenkuytu ◽  
Bunyemin Cosut
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Treatment ◽  
Singlet Oxygen ◽  
Side Effect ◽  
Side Effect Profile ◽  
High Ability ◽  
Lower Side ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Promising Strategy

Photodynamic therapy (PDT) is a promising strategy in cancer treatment with its relatively lower side effect profile. Undoubtedly, the key component of PDT is the photosensitizers with a high ability...

Achieving high singlet-oxygen generation by applying the heavy-atom effect to thermally activated delayed fluorescent materials

2021 ◽  
Author(s):  
Ya-Fang Xiao ◽  
Jia-Xiong Chen ◽  
Wen-Cheng Chen ◽  
Xiuli Zheng ◽  
Chen Cao ◽  
...  
Keyword(s):  
Singlet Oxygen ◽  
Heavy Atom ◽  
Synergetic Effect ◽  
Heavy Atom Effect ◽  
Oxygen Generation ◽  
Thermally Activated ◽  
Singlet Oxygen Generation ◽  
Fluorescent Materials ◽  
Atom Effect

Applying the heavy-atom effect to TADF photosensitizers achieves ultra-high 1O2 generation (ФΔ = 0.91) by the synergetic effect of small ΔEST and considerable SOC.

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