Biodegradable Nano-photosensitizer with Photoactivatable Singlet Oxygen Generation for Synergistic Phototherapy

2021 ◽  
Author(s):  
Jiaxin Shen ◽  
Dandan Chen ◽  
Ye Liu ◽  
Guoyang Gao ◽  
Zhihe Liu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Singlet Oxygen ◽  
Near Infrared ◽  
Promising Method ◽  
Normal Cells ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Nir Light

Photodynamic therapy (PDT) is a promising method for cancer therapy and also may initiate unexpected damages to normal cells and tissues. Herein, we developed a near-infrared (NIR) light-activatable nanophotosensitizer, which...

scholarly journals Highly efficient singlet oxygen generation, two-photon photodynamic therapy and melanoma ablation by rationally designed mitochondria-specific near-infrared AIEgens

2020 ◽  
Vol 11 (9) ◽  
pp. 2494-2503 ◽  
Author(s):  
Zheng Zheng ◽  
Haixiang Liu ◽  
Shaodong Zhai ◽  
Haoke Zhang ◽  
Guogang Shan ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Near Infrared ◽  
Molecular Engineering ◽  
Photon Absorption ◽  
Oxygen Generation ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Singlet Oxygen Generation ◽  
Highly Efficient

Mitochondria-targeted photosensitizers with highly efficient singlet oxygen generation, bright near-infrared AIE and good two-photon absorption are obtained through ingenious molecular engineering for cancer cell-selective photodynamic therapy.

Singlet oxygen generation under NIR light and visible light excitations of photosensitizers on upconversion nanoparticle surface

RSC Advances ◽  
2015 ◽  
Vol 5 (83) ◽  
pp. 67892-67895 ◽  
Author(s):  
Padmanabh Joshi ◽  
Tevhide Ozkaya Ahmadov ◽  
Peng Wang ◽  
Peng Zhang
Keyword(s):  
Visible Light ◽  
Singlet Oxygen ◽  
Near Infrared ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Nir Light ◽  
Nanoparticle Surface

Effects of beef tissue on singlet oxygen generation under both near-infrared and visible light excitations are investigated and compared.

Design of Novel Photosensitizers and Controlled Singlet Oxygen Generation for Photodynamic Therapy

2021 ◽  
Author(s):  
Esra Tanrıverdi Eçik ◽  
Onur BULUT ◽  
Hasan Hüseyin Kazan ◽  
Elif Şenkuytu ◽  
Bunyemin Cosut
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Treatment ◽  
Singlet Oxygen ◽  
Side Effect ◽  
Side Effect Profile ◽  
High Ability ◽  
Lower Side ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Promising Strategy

Photodynamic therapy (PDT) is a promising strategy in cancer treatment with its relatively lower side effect profile. Undoubtedly, the key component of PDT is the photosensitizers with a high ability...

scholarly journals Correction: Efficient singlet oxygen generation from sugar pendant C60 derivatives for photodynamic therapy

2015 ◽  
Vol 51 (99) ◽  
pp. 17631-17632 ◽  
Author(s):  
Shigenobu Yano ◽  
Masami Naemura ◽  
Akio Toshimitsu ◽  
Motofusa Akiyama ◽  
Atsushi Ikeda ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
C60 Derivatives

Correction for ‘Efficient singlet oxygen generation from sugar pendant C60 derivatives for photodynamic therapy’ by Shigenobu Yano et al., Chem. Commun., 2015, DOI: 10.1039/c5cc07353g.

scholarly journals Nucleotide-derived theranostic nanodots with intrinsic fluorescence and singlet oxygen generation for bioimaging and photodynamic therapy

2019 ◽  
Vol 1 (6) ◽  
pp. 2250-2257 ◽  
Author(s):  
Xin Ting Zheng ◽  
Yee Ching Lai ◽  
Yen Nee Tan
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Intrinsic Fluorescence ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Bright Fluorescence ◽  
Theranostic Applications

We report a new way to engineer nanomaterials from biomolecules (N-dots) with bright fluorescence and high singlet oxygen generation towards theranostic applications.

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