Self-Assembly of Pluronic F127—Silica Spherical Core–Shell Nanoparticles in Cubic Close-Packed Structures

A targeting drug delivery system using folate-conjugated pluronic F127/chitosan core-shell nanoparticles was developed to deliver doxorubicin (DOX) to the target cancer cells. First, DOX was encapsulated in pluronic F127 micelle cores in the presence of sodium dodecyl sulfate (SDS) by a self-assembly method. To form a shell, a layer of either chitosan or folate-conjugated chitosan was deposited onto the pluronic micelles. The encapsulation efficiency was approximately58.1±4.7%. The average size of the core-shell nanoparticles was37.4±2.0 nm, while the zeta potential was12.9±2.3 mV, indicating the presence of a shell layer and more stable particles. In anin vitroDOX release study, an initial burst release, followed by a sustained release, was observed within 24 hours. In addition, the core-shell nanoparticles showed greater cytotoxicity towards MCF-7 cells than free DOX, suggesting a better therapeutic efficacy in treating cancer.

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Magnetic-field-induced self-assembly of FeCo/CoFe2O4 core/shell nanoparticles with tunable collective magnetic properties

Nanoscale ◽

10.1039/d1nr00136a ◽

2021 ◽

Vol 13 (8) ◽

pp. 4519-4529

Author(s):

J. Mohapatra ◽

J. Elkins ◽

M. Xing ◽

D. Guragain ◽

Sanjay R. Mishra ◽

...

Keyword(s):

Magnetic Field ◽

Magnetic Properties ◽

Physical Properties ◽

Self Assembly ◽

Core Shell ◽

Shell Nanoparticles ◽

Novel Approach ◽

Core Shell Nanoparticles

Self-assembly of nanoparticles into ordered patterns is a novel approach to build up new consolidated materials with desired collective physical properties.

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Hybrid Core-Shell Nanoparticles by “Plug and Play” Self-Assembly

Chemistry - A European Journal ◽

10.1002/chem.201804155 ◽

2018 ◽

Vol 24 (67) ◽

pp. 17672-17676 ◽

Cited By ~ 5

Author(s):

Benjamin Pacaud ◽

Loïc Leclercq ◽

Jean-François Dechézelles ◽

Véronique Nardello-Rataj

Keyword(s):

Self Assembly ◽

Core Shell ◽

Plug And Play ◽

Shell Nanoparticles ◽

Core Shell Nanoparticles

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Investigation on the self-assembly of magnetic core-shell nanoparticles under soft-magnet element by using discrete element method

Journal of Magnetism and Magnetic Materials ◽

10.1016/j.jmmm.2018.11.038 ◽

2019 ◽

Vol 475 ◽

pp. 152-159 ◽

Cited By ~ 1

Author(s):

Zongqian Shi ◽

Jiajia Sun ◽

Shuang Chen ◽

Shenli Jia

Keyword(s):

Discrete Element Method ◽

Self Assembly ◽

Discrete Element ◽

Magnetic Core ◽

The Self ◽

Core Shell ◽

Shell Nanoparticles ◽

Core Shell Nanoparticles ◽

Element Method

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Interaction-Induced Self-Assembly of Au@La2O3 Core–Shell Nanoparticles on La2O2CO3 Nanorods with Enhanced Catalytic Activity and Stability for Soot Oxidation

ACS Catalysis ◽

10.1021/acscatal.9b00107 ◽

2019 ◽

Vol 9 (4) ◽

pp. 3700-3715 ◽

Cited By ~ 33

Author(s):

Qiangqiang Wu ◽

Jing Xiong ◽

Yilin Zhang ◽

Xuelei Mei ◽

Yuechang Wei ◽

...

Keyword(s):

Catalytic Activity ◽

Self Assembly ◽

Soot Oxidation ◽

Core Shell ◽

Shell Nanoparticles ◽

Core Shell Nanoparticles

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Synthesis and Magnetic Properties of FePt Nanoparticles with Hard Nonmagnetic Shells

Journal of Nanoscience and Nanotechnology ◽

10.1166/jnn.2007.18034 ◽

2007 ◽

Vol 7 (1) ◽

pp. 350-355 ◽

Cited By ~ 3

Author(s):

Shishou Kang ◽

Shifan Shi ◽

G. X. Miao ◽

Zhiyong Jia ◽

David E. Nikles ◽

...

Keyword(s):

Magnetic Properties ◽

Crystallographic Orientation ◽

Sol Gel ◽

Molar Ratio ◽

Core Shell ◽

Fept Nanoparticles ◽

Shell Nanoparticles ◽

Spherical Core ◽

Size And Morphology ◽

Core Shell Nanoparticles

Chemically synthesized FePt nanoparticles were coated with nonmagnetic SiO2 and MnO shells by sol–gel and polyol processes. TEM images show that the FePt/SiO2 nanoparticles exhibit a thick spherical shell. The size and morphology of the MnO shell can be controlled by changing the reaction temperature, the molar ratio of surfactants/Mn(acac)2, and/or the concentration of precursor. The morphology of the MnO shell can be either spherical-like or cubic-like, depending on whether the molar ratio of surfactants/Mn(acac)2 is less than or larger than 2. From XRD measurements, the spherical core/shell nanoparticles exhibit 3D random crystallographic orientation, while the cubic core/shell nanoparticles prefer (200) texture. The magnetic moment of FePt particles can be enhanced by coating with SiO2 and MnO shells. Furthermore, the agglomeration of FePt particles upon the thermal annealing can be significantly inhibited with SiO2 and MnO shells.

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