Rational Design, Synthesis, and Biological Evaluation of 7-Azaindole Derivatives as Potent Focused Multi-Targeted Kinase Inhibitors

Rational Design, Synthesis and Biological Evaluation of Novel Derivatives Based on in vivo Metabolism of Natural Product β-elemene

Letters in Drug Design & Discovery ◽

10.2174/1570180814666171108093021 ◽

2018 ◽

Vol 15 (8) ◽

pp. 905-912 ◽

Cited By ~ 1

Author(s):

Renren Bai ◽

Xiaokang Jie ◽

Eric Salgado ◽

Jian Sun ◽

Yao Zhu ◽

...

Keyword(s):

Natural Product ◽

Rational Design ◽

Biological Evaluation ◽

In Vivo Metabolism ◽

Design Synthesis ◽

3,5-Diaryl-1H-pyrazolo[3,4-b]pyridines as potent tubulin polymerization inhibitors: Rational design, synthesis and biological evaluation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.12.053 ◽

2019 ◽

Vol 168 ◽

pp. 426-435 ◽

Cited By ~ 14

Author(s):

Min'an Zhai ◽

Shiyuan Liu ◽

Meiqi Gao ◽

Long Wang ◽

Jun Sun ◽

...

Keyword(s):

Rational Design ◽

Biological Evaluation ◽

Tubulin Polymerization ◽

Design Synthesis ◽

Tubulin Polymerization Inhibitors ◽

WITHDRAWN: Design, synthesis and biological evaluation of 3-substituted-4-anilinequinoline as EGFR tyrosine kinase inhibitors

10.1016/j.bmcl.2012.10.030 ◽

2012 ◽

Author(s):

Yongjun Mao ◽

Kai Xie ◽

Wenxiu Zhu ◽

Jianfeng Li ◽

Hua Xie ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors ◽

Design, synthesis and biological evaluation of potent EGFR kinase inhibitors against 19D/T790M/C797S mutation

10.1016/j.bmcl.2020.127327 ◽

2020 ◽

Vol 30 (16) ◽

pp. 127327

Author(s):

Zhicheng Su ◽

Tingyuan Yang ◽

Jie Wang ◽

Mengzhen Lai ◽

Linjiang Tong ◽

...

Keyword(s):

Kinase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Egfr Kinase

Rational design, synthesis and biological evaluation of ubiquinone derivatives as IDO1 inhibitors

Bioorganic Chemistry ◽

10.1016/j.bioorg.2019.03.044 ◽

2019 ◽

Vol 89 ◽

pp. 102870 ◽

Cited By ~ 5

Author(s):

Yuyang Ding ◽

Fei Tang ◽

Xiaoqian Xue ◽

Jinfeng Luo ◽

Muzammal Hussain ◽

...

Keyword(s):

Rational Design ◽

Biological Evaluation ◽

Design Synthesis ◽

Design, Synthesis, and Biological Evaluation of Chromone-Based p38 MAP Kinase Inhibitors

Journal of Medicinal Chemistry ◽

10.1021/jm200818j ◽

2011 ◽

Vol 54 (20) ◽

pp. 7427-7431 ◽

Cited By ~ 28

Author(s):

Christine Dyrager ◽

Linda Nilsson Möllers ◽

Linda Karlsson Kjäll ◽

John Patrick Alao ◽

Peter Dinér ◽

...

Keyword(s):

Map Kinase ◽

Kinase Inhibitors ◽

Biological Evaluation ◽

P38 Map Kinase ◽

Design Synthesis ◽

P38 Map Kinase Inhibitors ◽

Design, synthesis and biological evaluation of novel pyrimidine, 3-cyanopyridine and m-amino-N-phenylbenzamide based monocyclic EGFR tyrosine kinase inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2013.03.053 ◽

2013 ◽

Vol 21 (11) ◽

pp. 3090-3104 ◽

Cited By ~ 18

Author(s):

Yongjun Mao ◽

Wenxiu Zhu ◽

Xiaoguang Kong ◽

Zhen Wang ◽

Hua Xie ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Egfr Tyrosine Kinase ◽

Egfr Tyrosine Kinase Inhibitors ◽

α1-Adrenoceptor antagonists. rational design, synthesis and biological evaluation of new trazodone-like compounds

10.1016/s0960-894x(01)00772-7 ◽

2002 ◽

Vol 12 (3) ◽

pp. 437-440 ◽

Cited By ~ 18

Author(s):

Laura Betti ◽

Maurizio Botta ◽

Federico Corelli ◽

Monia Floridi ◽

Paola Fossa ◽

...

Keyword(s):

Rational Design ◽

Biological Evaluation ◽

Design Synthesis ◽

Design, Synthesis, and Biological Evaluation of Novel Type I1/2 p38α MAP Kinase Inhibitors with Excellent Selectivity, High Potency, and Prolonged Target Residence Time by Interfering with the R-Spine

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.7b00745 ◽

2017 ◽

Vol 60 (19) ◽

pp. 8027-8054 ◽

Cited By ~ 11

Author(s):

Niklas M. Walter ◽

Heike K. Wentsch ◽

Mike Bührmann ◽

Silke M. Bauer ◽

Eva Döring ◽

...

Keyword(s):

Map Kinase ◽

Residence Time ◽

Kinase Inhibitors ◽

Biological Evaluation ◽

High Potency ◽

Design Synthesis ◽

P38α Map Kinase ◽

Synthesis And Biological Evaluation ◽

Excellent Selectivity

The design, synthesis, and biological evaluation of potent receptor tyrosine kinase inhibitors

Receptor Tyrosine Kinase Inhibitors

10.1016/j.bmcl.2012.06.029 ◽

2012 ◽

Vol 22 (15) ◽

pp. 4979-4985 ◽

Cited By ~ 13

Author(s):

Moon H. Kim ◽

Amy Lew Tsuhako ◽

Erick W. Co ◽

Dana T. Aftab ◽

Frauke Bentzien ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽