Stereoselective Synthesis of Dihydrocoumarins via [1,2]-Phospha-Brook Rearrangement in Three-Component Coupling Reaction of α-Ketoesters, o-Quinone Methides, and Dialkyl Phosphites

2021 ◽  
Author(s):  
Ravneet Kaur ◽  
Dipak Singh ◽  
Ravi P. Singh
Keyword(s):  
Stereoselective Synthesis ◽  
Coupling Reaction ◽  
Quinone Methides ◽  
Brook Rearrangement ◽  
Dialkyl Phosphites ◽  
Three Component Coupling

Brønsted base-catalyzed three-component coupling reaction of α-ketoesters, imines, and diethyl phosphite utilizing [1,2]-phospha-Brook rearrangement

2016 ◽  
Vol 14 (20) ◽  
pp. 4704-4711 ◽  
Author(s):  
Azusa Kondoh ◽  
Masahiro Terada
Keyword(s):  
Coupling Reaction ◽  
Base Catalysis ◽  
Diethyl Phosphite ◽  
Brook Rearrangement ◽  
Brønsted Base ◽  
Three Component Coupling

A three-component coupling reaction of α-ketoesters, imines, and diethyl phosphite under Brønsted base catalysis was developed by utilizing the [1,2]-phospha-Brook rearrangement.

scholarly journals N-Alkylation/aldol reaction of α-aldimino thioesters: a facile three-component coupling reaction

RSC Advances ◽  
2021 ◽  
Vol 11 (22) ◽  
pp. 13097-13104
Author(s):  
Makoto Shimizu ◽  
Asako Higashino ◽  
Isao Mizota ◽  
Yusong Zhu
Keyword(s):  
Aldol Reaction ◽  
Coupling Reaction ◽  
Three Component Coupling

Treatment of α-aldimino thioesters with dialkylzinc reagents in the presence of aldehydes or imines gives three-component coupling products in good yields with good to high anti-selectivities.

Pd-Catalyzed Coupling Reaction of Acetylenes, Iodotrimethylsilane, and Organozinc Reagents for the Stereoselective Synthesis of Vinylsilanes

1995 ◽  
Vol 60 (6) ◽  
pp. 1834-1840 ◽  
Author(s):  
Naoto Chatani ◽  
Nobuyoshi Amishiro ◽  
Takaya Morii ◽  
Toshiaki Yamashita ◽  
Shinji Murai
Keyword(s):  
Stereoselective Synthesis ◽  
Coupling Reaction ◽  
Organozinc Reagents

A 2:1 Coupling Reaction of Arynes with Aldehydes viao-Quinone Methides:  Straightforward Synthesis of 9-Arylxanthenes

2004 ◽  
Vol 6 (22) ◽  
pp. 4049-4051 ◽  
Author(s):  
Hiroto Yoshida ◽  
Masahiko Watanabe ◽  
Hiroyuki Fukushima ◽  
Joji Ohshita ◽  
Atsutaka Kunai
Keyword(s):  
Coupling Reaction ◽  
Quinone Methides

scholarly journals PEG-embedded KBr3: A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines

2011 ◽  
Vol 7 ◽  
pp. 1334-1341 ◽  
Author(s):  
Sanny Verma ◽  
Suman L Jain ◽  
Bir Sain
Keyword(s):  
Coupling Reaction ◽  
Recyclable Catalyst ◽  
Efficient Synthesis ◽  
Molecular Bromine ◽  
Keto Ester ◽  
One Step ◽  
High Yields ◽  
Multicomponent Coupling ◽  
Three Component Coupling

PEG-embedded potassium tribromide ([K+PEG]Br3 −) was found to be an efficient and recyclable catalyst for the synthesis of functionalized piperidines in high yields in a one step, three component coupling between aldehyde, amine and β-keto ester. At the end of the reaction the [K+PEG]Br3 − was readily regenerated from the reaction mixture by treating the residue containing [K+PEG]Br− with molecular bromine.

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