Biological-Profiling-Based Systematic Analysis of Rhizoma Coptidis from Different Growing Regions and Its Anticholesterol Biosynthesis Activity on HepG2 Cells

2018 ◽  
Vol 15 (6) ◽  
pp. 2234-2245
Author(s):  
Juan Feng ◽  
Haoxun Li ◽  
Wenlong Zhao ◽  
Honglei Dang ◽  
Ruijun Wang ◽  
...  
Keyword(s):  
Hepg2 Cells ◽  
Systematic Analysis ◽  
Rhizoma Coptidis

Synergetic cholesterol-lowering effects of main alkaloids from Rhizoma Coptidis in HepG2 cells and hypercholesterolemia hamsters

Life Sciences ◽  
2016 ◽  
Vol 151 ◽  
pp. 50-60 ◽  
Author(s):  
Shuming Kou ◽  
Bing Han ◽  
Yue Wang ◽  
Tao Huang ◽  
Kai He ◽  
...  
Keyword(s):  
Hepg2 Cells ◽  
Cholesterol Lowering ◽  
Rhizoma Coptidis

Preparatory Procedures for Electron Microscopic Analysis at the Molecular Level of Resolution

1978 ◽  
Vol 36 (3) ◽  
pp. 516-520
Author(s):  
F.J. Sjostrand
Keyword(s):  
Electron Microscope ◽  
Molecular Level ◽  
Microscopic Analysis ◽  
Resolving Power ◽  
Cellular Structures ◽  
Electron Microscopic ◽  
Systematic Analysis ◽  
Technical Developments ◽  
Thin Sectioning ◽  
Obvious Reason

In the 1940's and 1950's electron microscopy conferences were attended with everybody interested in learning about the latest technical developments for one very obvious reason. There was the electron microscope with its outstanding performance but nobody could make very much use of it because we were lacking proper techniques to prepare biological specimens. The development of the thin sectioning technique with its perfectioning in 1952 changed the situation and systematic analysis of the structure of cells could now be pursued. Since then electron microscopists have in general become satisfied with the level of resolution at which cellular structures can be analyzed when applying this technique. There has been little interest in trying to push the limit of resolution closer to that determined by the resolving power of the electron microscope.

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