Asymmetric Transfer Hydrogenation of Densely Functionalized Diheteroaryl and Diaryl Ketones by a Ru-Catalyst of Minimal Stereogenicity

2020 ◽  
Vol 22 (21) ◽  
pp. 8458-8463
Author(s):  
Dongxu He ◽  
Xingjun Xu ◽  
Yi Lu ◽  
Min-Jie Zhou ◽  
Xiangyou Xing
Keyword(s):  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Ru Catalyst

Phosphonate-containing polystyrene copolymer-supported Ru catalyst for asymmetric transfer hydrogenation in water

RSC Advances ◽  
2013 ◽  
Vol 3 (19) ◽  
pp. 6747 ◽  
Author(s):  
Xiao Xu ◽  
Rui Wang ◽  
Jingwei Wan ◽  
Xuebing Ma ◽  
Jingdong Peng
Keyword(s):  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Ru Catalyst

Asymmetric transfer hydrogenation of ketones with a polyethylene glycol bound Ru catalyst in water

2008 ◽  
Vol 19 (7) ◽  
pp. 832-837 ◽  
Author(s):  
Juntao Liu ◽  
Yougui Zhou ◽  
Yinuo Wu ◽  
Xingshu Li ◽  
Albert S.C. Chan
Keyword(s):  
Polyethylene Glycol ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Ru Catalyst

A Versatile Ru Catalyst for the Asymmetric Transfer Hydrogenation of Both Aromatic and Aliphatic Sulfinylimines

2012 ◽  
Vol 18 (7) ◽  
pp. 1969-1983 ◽  
Author(s):  
Óscar Pablo ◽  
David Guijarro ◽  
Gábor Kovács ◽  
Agustí Lledós ◽  
Gregori Ujaque ◽  
...  
Keyword(s):  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Ru Catalyst

ChemInform Abstract: Asymmetric Transfer Hydrogenation of Ketones with a Polyethylene Glycol Bound Ru Catalyst in Water.

ChemInform ◽  
2008 ◽  
Vol 39 (40) ◽  
Author(s):  
Juntao Liu ◽  
Yougui Zhou ◽  
Yinuo Wu ◽  
Xingshu Li ◽  
Albert S. C. Chan
Keyword(s):  
Polyethylene Glycol ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Ru Catalyst

ChemInform Abstract: A Versatile Ru Catalyst for the Asymmetric Transfer Hydrogenation of Both Aromatic and Aliphatic Sulfinylimines.

ChemInform ◽  
2012 ◽  
Vol 43 (26) ◽  
pp. no-no
Author(s):  
Oscar Pablo ◽  
David Guijarro ◽  
Gabor Kovacs ◽  
Agusti Lledos ◽  
Gregori Ujaque ◽  
...  
Keyword(s):  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Ru Catalyst

scholarly journals Arene‐Immobilized Ru(II)/TsDPEN Complexes: Synthesis and Applications to the Asymmetric Transfer Hydrogenation of Ketones

2020 ◽  
Author(s):  
Simon Doherty ◽  
Julian G. Knight ◽  
Hind Alshaikh ◽  
James Wilson ◽  
Paul G. Waddell ◽  
...  
Keyword(s):  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation

scholarly journals Design of Iridium N-Heterocyclic Carbene Amino Acid Catalysts for Asymmetric Transfer Hydrogenation of Aryl Ketones

Catalysts ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 671
Author(s):  
Chad M. Bernier ◽  
Joseph S. Merola
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Enantiomeric Excess ◽  
Transfer Hydrogenation ◽  
Acid Catalysts ◽  
Asymmetric Transfer Hydrogenation ◽  
Reaction Conditions ◽  
Chiral Complexes ◽  
Acetophenone Derivatives ◽  
Aryl Ketones

A series of chiral complexes of the form Ir(NHC)2(aa)(H)(X) (NHC = N-heterocyclic carbene, aa = chelated amino acid, X = halide) was synthesized by oxidative addition of -amino acids to iridium(I) bis-NHC compounds and screened for asymmetric transfer hydrogenation of ketones. Following optimization of the reaction conditions, NHC, and amino acid ligands, high enantioselectivity was achieved when employing the Ir(IMe)2(l-Pro)(H)(I) catalyst (IMe = 1,3-dimethylimidazol-2-ylidene), which asymmetrically reduces a range of acetophenone derivatives in up to 95% enantiomeric excess.

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