Enantioselective Radical SN2-Type Alkylation of Morita–Baylis–Hillman Adducts Using Dual Photoredox/Palladium Catalysis

A CF3SO2Na/Pd(OAc)2 co-catalyzed strategy is developed to produce aryl ketones via visible-light-induced decarboxylative cross-coupling of α-oxocarboxylic acids and aryl boronic acids. This process was perfomed under air at room temperature,...

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Recent advance in NHC-palladium catalysis for alkynes chemistry: versatile synthesis and applications

Organic Chemistry Frontiers ◽

10.1039/d1qo00111f ◽

2021 ◽

Author(s):

Jianxiao Li ◽

Dan He ◽

Zidong Lin ◽

Wanqing Wu ◽

Huanfeng Jiang

Keyword(s):

Transition Metal ◽

Palladium Catalysis ◽

Metal Catalysts ◽

Chemical Transformations ◽

The Past ◽

Transition Metal Catalyzed ◽

Metal Catalyzed

During the past decades, alkynes chemistry has attracted considerable attention owing to their unique and idiographic nucleophilic and electrophilic properties in transition-metal-catalyzed chemical transformations. Among the various metal catalysts, palladium...

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Temporary (PO) directing group enabled carbazole ortho arylation via palladium catalysis

Chemical Communications ◽

10.1039/d0cc07596e ◽

2021 ◽

Vol 57 (16) ◽

pp. 2021-2024

Author(s):

Zhi-Chao Qi ◽

Qin-Xin Lou ◽

Yuan Niu ◽

Shang-Dong Yang

Keyword(s):

Palladium Catalysis ◽

Palladium Catalyzed ◽

Directing Group

An efficient palladium-catalyzed, temporary P(O) directing group assisted C–H bond arylation of carbazoles was achieved, accompanied by the directing group being self-shed spontaneously.

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Intermolecular C–H Amidation of Alkenes with Carbon Monoxide and Azides via Tandem Palladium Catalysis

Synthesis ◽

10.1055/a-1401-4486 ◽

2021 ◽

Author(s):

Zheng-Yang Gu ◽

Yang Wu ◽

Feng Jin ◽

Bao Xiaoguang ◽

Ji-Bao Xia

Keyword(s):

Carbon Monoxide ◽

Palladium Catalysis ◽

Computational Studies ◽

Organic Azides ◽

Reaction Proceeds ◽

Palladium Catalyzed ◽

Directing Group ◽

And Control

An atom- and step-economic intermolecular multi-component palladium-catalyzed C–H amidation of alkenes with carbon monoxide and organic azides has been developed for the synthesis of alkenyl amides. The reaction proceeds efficiently without an ortho-directing group on the alkene substrates. Nontoxic dinitrogen is generated as the sole by-product. Computational studies and control experiments have revealed that the reaction takes place via an unexpected mechanism by tandem palladium catalysis.

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