Bifacial PNAs Destabilize MALAT1 by 3′ A-Tail Displacement from the U-Rich Internal Loop

AbstractThe stem-loop (SL1) is the 5'-terminal structural element within the single-stranded SARS-CoV-2 RNA genome. It is formed by nucleotides 7–33 and consists of two short helical segments interrupted by an asymmetric internal loop. This architecture is conserved among Betacoronaviruses. SL1 is present in genomic SARS-CoV-2 RNA as well as in all subgenomic mRNA species produced by the virus during replication, thus representing a ubiquitous cis-regulatory RNA with potential functions at all stages of the viral life cycle. We present here the 1H, 13C and 15N chemical shift assignment of the 29 nucleotides-RNA construct 5_SL1, which denotes the native 27mer SL1 stabilized by an additional terminal G-C base-pair.

Hydrodynamic characteristics in an inverse internal-loop airlift-driven fibrous-bed bioreactor

Chemical Engineering Science ◽

10.1016/j.ces.2009.09.023 ◽

2010 ◽

Vol 65 (2) ◽

pp. 692-707 ◽

Cited By ~ 8

Author(s):

Peter M. Kilonzo ◽

Argyrios Margaritis ◽

M.A. Bergougnou

Keyword(s):

Hydrodynamic Characteristics ◽

Internal Loop ◽

Fibrous Bed Bioreactor

Identification of flow regime transitions in an annulus sparged internal loop airlift reactor based on higher order statistics and Winger trispectrum

Chemical Engineering Science ◽

10.1016/j.ces.2011.07.018 ◽

2011 ◽

Vol 66 (21) ◽

pp. 5224-5235 ◽

Cited By ~ 8

Author(s):

Lijia Luo ◽

Yuanyuan Xu ◽

Jingqi Yuan

Keyword(s):

Order Statistics ◽

Flow Regime ◽

Higher Order ◽

Airlift Reactor ◽

Higher Order Statistics ◽

Internal Loop ◽

Regime Transitions

Nd:YAG Oscillator Power Amplifier Using Photorefractive BaTiO/sub 3/:Rh Internal Loop and Ring Self-Pumped Phase Conjugate Mirrors

CLEO/Europe Conference on Lasers and Electro-Optics ◽

10.1109/cleoe.1998.719320 ◽

2005 ◽

Author(s):

N. Huot ◽

J.M.C. Jonathan ◽

G. Pauliat ◽

G. Roosen ◽

A. Brignon ◽

...

Keyword(s):

Power Amplifier ◽

Phase Conjugate ◽

Internal Loop

Simultaneous sewage sludge digestion and metal leaching using an internal loop reactor

Water Research ◽

10.1016/s0043-1354(97)00112-7 ◽

1997 ◽

Vol 31 (10) ◽

pp. 2638-2654 ◽

Cited By ~ 20

Author(s):

H. Benmoussa ◽

R.D. Tyagi ◽

P.G.C. Campbell

Keyword(s):

Sewage Sludge ◽

Metal Leaching ◽

Loop Reactor ◽

Internal Loop ◽

Sludge Digestion

Numerical simulation and physical modeling of the hydrodynamics in an air-lift internal loop reactor

Chemical Engineering Science ◽

10.1016/s0009-2509(97)00224-8 ◽

1997 ◽

Vol 52 (21-22) ◽

pp. 3787-3793 ◽

Cited By ~ 42

Author(s):

A. Cockx ◽

A. Liné ◽

M. Roustan ◽

Z. Do-Quang ◽

V. Lazarova

Keyword(s):

Numerical Simulation ◽

Physical Modeling ◽

Loop Reactor ◽

Internal Loop ◽

Air Lift

Influence of biomass on hydrodynamics of an internal loop airlift reactor

Chemical Papers ◽

10.2478/s11696-006-0080-2 ◽

2006 ◽

Vol 60 (6) ◽

Cited By ~ 1

Author(s):

M. Juraščík ◽

M. Hucík ◽

I. Sikula ◽

J. Annus ◽

J. Markoš

Keyword(s):

Aspergillus Niger ◽

Gluconic Acid ◽

Solid Phase ◽

Biomass Concentration ◽

Airlift Reactor ◽

Phase System ◽

Two Phase ◽

Experimental Conditions ◽

Internal Loop ◽

Three Phase

AbstractThe effect of the biomass presence on the overall circulation velocity, the linear velocities both in the riser and the downcomer and the overall gas hold-up was studied in a three-phase internal loop airlift reactor (ILALR). The measured data were compared with those obtained using a two-phase system (air—water). All experiments were carried out in a 40 dm3 ILALR at six different biomass concentrations (ranging from 0 g dm−3 to 7.5 g dm−3), at a temperature of 30°C, under atmospheric pressure. Air and water were used as the gas and liquid model media, respectively. Pellets of Aspergillus niger produced during the fermentation of glucose to gluconic acid in the ILALR were considered solid phase. In addition, liquid velocities were measured during the fermentation of glucose to gluconic acid using Aspergillus niger. All measurements were performed in a bubble circulation regime. At given experimental conditions the effect of the biomass on the circulation velocities in the ILALR was negligible. However, increasing of the biomass concentration led to lower values of the total gas hold-up.