scholarly journals Structure-Guided Design of Novel l-Cysteine Derivatives as Potent KSP Inhibitors

2015 ◽  
Vol 6 (9) ◽  
pp. 1004-1009 ◽  
Author(s):  
Naohisa Ogo ◽  
Yoshinobu Ishikawa ◽  
Jun-ichi Sawada ◽  
Kenji Matsuno ◽  
Akihiro Hashimoto ◽  
...  
Keyword(s):  
Ksp Inhibitors

Synthesis, docking studies, and in silico ADMET predictions of some new derivatives of pyrimidine as potential KSP inhibitors

2014 ◽  
Vol 24 (1) ◽  
pp. 304-315 ◽  
Author(s):  
Umer Rashid ◽  
Syed Fahad Hassan ◽  
Samina Nazir ◽  
Abdul Wadood ◽  
Muhammad Waseem ◽  
...  
Keyword(s):  
In Silico ◽  
Docking Studies ◽  
In Silico Admet ◽  
Ksp Inhibitors ◽  
Derivatives Of

Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP

2005 ◽  
Vol 15 (8) ◽  
pp. 2041-2045 ◽  
Author(s):  
Christopher D. Cox ◽  
Michael J. Breslin ◽  
Brenda J. Mariano ◽  
Paul J. Coleman ◽  
Carolyn A. Buser ◽  
...  
Keyword(s):  
Selective Inhibitors ◽  
Kinesin Spindle Protein ◽  
Ksp Inhibitors

KSP Inhibitors as Antimitotic Agents

2014 ◽  
Vol 14 (20) ◽  
pp. 2286-2311 ◽  
Author(s):  
Concepcion Perez-Melero
Keyword(s):  
Ksp Inhibitors

Abstract 3234: Development of potent and selective antibody-drug conjugates with pyrrole-based KSP inhibitors as novel payload class

2017 ◽  
Author(s):  
Hans-Georg Lerchen ◽  
Sven Wittrock ◽  
Nils Griebenow ◽  
Mario Lobell ◽  
Anne-Sophie Rebstock ◽  
...  
Keyword(s):  
Antibody Drug Conjugates ◽  
Drug Conjugates ◽  
Ksp Inhibitors ◽  
Antibody Drug

Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP

2007 ◽  
Vol 17 (20) ◽  
pp. 5677-5682 ◽  
Author(s):  
Anthony J. Roecker ◽  
Paul J. Coleman ◽  
Swati P. Mercer ◽  
John D. Schreier ◽  
Carolyn A. Buser ◽  
...  
Keyword(s):  
Design And Synthesis ◽  
Kinesin Spindle Protein ◽  
Ksp Inhibitors
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