scholarly journals Design and Development of Small-Molecule Arylaldoxime/5-Nitroimidazole Hybrids as Potent Inhibitors of MARK4: A Promising Approach for Target-Based Cancer Therapy

ACS Omega ◽  
2020 ◽  
Vol 5 (36) ◽  
pp. 22759-22771 ◽  
Author(s):  
Mudasir Nabi Peerzada ◽  
Parvez Khan ◽  
Nashrah Sharif Khan ◽  
Fernando Avecilla ◽  
Shadab Miyan Siddiqui ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Small Molecule ◽  
Design And Development

scholarly journals Discovery of fruquintinib, a potent and highly selective small molecule inhibitor of VEGFR 1, 2, 3 tyrosine kinases for cancer therapy

2014 ◽  
Vol 15 (12) ◽  
pp. 1635-1645 ◽  
Author(s):  
Qiaoling Sun ◽  
Jinghong Zhou ◽  
Zheng Zhang ◽  
Mingchuan Guo ◽  
Junqing Liang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Small Molecule ◽  
Tyrosine Kinases ◽  
Small Molecule Inhibitor ◽  
Molecule Inhibitor

scholarly journals Diverse Landscape Of Dermatologic Toxicities From Small Molecule Inhibitor Cancer Therapy

2021 ◽  
Author(s):  
Riyad N. H. Seervai ◽  
Woo Cheal Cho ◽  
Emily Y. Chu ◽  
Mario L. Marques‐Piubelli ◽  
Debora A. Ledesma ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Small Molecule ◽  
Small Molecule Inhibitor ◽  
Molecule Inhibitor

scholarly journals Preclinical Characterization of Signal Transducer and Activator of Transcription 3 Small Molecule Inhibitors for Primary and Metastatic Brain Cancer Therapy

2014 ◽  
Vol 349 (3) ◽  
pp. 458-469 ◽  
Author(s):  
Hikmat H. Assi ◽  
Chris Paran ◽  
Nathan VanderVeen ◽  
Jonathan Savakus ◽  
Robert Doherty ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Small Molecule ◽  
Brain Cancer ◽  
Small Molecule Inhibitors ◽  
Signal Transducer ◽  
Transcription 3

A Unique Self-Reporting Photosensitizer Enabling Simultaneous Photodynamic Therapy and Real-Time Monitoring Phototheranostic Process in a Dynamic Dual-Color Mode

2021 ◽  
Author(s):  
Dong-Hui Wang ◽  
Li-Jian Chen ◽  
Xu Zhao ◽  
Xiu-Ping Yan
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Real Time ◽  
Small Molecule ◽  
Therapeutic Efficacy ◽  
Real Time Monitoring ◽  
Dual Color

Phototheranostics has attracted great interest in cancer therapy. Small-molecule self-reporting photosensitizers, one kind of idea agents in phototheranostics, enable simultaneous photodynamic therapy (PDT) and feedback of therapeutic efficacy. However, previous...

Tetraspanins: useful multifunction proteins for the possible design and development of small-molecule therapeutic tools

2020 ◽  
Author(s):  
Jean-Michel H. Robert ◽  
Nathalie Gisèle Amoussou ◽  
Hubert Le Mai ◽  
Cédric Logé ◽  
Sophie Brouard
Keyword(s):  
Small Molecule ◽  
Design And Development ◽  
Therapeutic Tools

scholarly journals Long-Pentraxin 3 Derivative as a Small-Molecule FGF Trap for Cancer Therapy

Cancer Cell ◽  
2015 ◽  
Vol 28 (3) ◽  
pp. 399 ◽  
Author(s):  
Roberto Ronca ◽  
Arianna Giacomini ◽  
Emanuela Di Salle ◽  
Daniela Coltrini ◽  
Katiuscia Pagano ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Small Molecule ◽  
Pentraxin 3
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