A Unique Self-Reporting Photosensitizer Enabling Simultaneous Photodynamic Therapy and Real-Time Monitoring Phototheranostic Process in a Dynamic Dual-Color Mode

2021 ◽  
Author(s):  
Dong-Hui Wang ◽  
Li-Jian Chen ◽  
Xu Zhao ◽  
Xiu-Ping Yan
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Real Time ◽  
Small Molecule ◽  
Therapeutic Efficacy ◽  
Real Time Monitoring ◽  
Dual Color

Phototheranostics has attracted great interest in cancer therapy. Small-molecule self-reporting photosensitizers, one kind of idea agents in phototheranostics, enable simultaneous photodynamic therapy (PDT) and feedback of therapeutic efficacy. However, previous...

scholarly journals Real-Time Monitoring of Photocytotoxicity in Nanoparticles-Based Photodynamic Therapy: A Model-Based Approach

PLoS ONE ◽  
2012 ◽  
Vol 7 (11) ◽  
pp. e48617 ◽  
Author(s):  
Hamanou Benachour ◽  
Thierry Bastogne ◽  
Magali Toussaint ◽  
Yosra Chemli ◽  
Aymeric Sève ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Real Time ◽  
Real Time Monitoring ◽  
Model Based

Smart multifunctional polyurethane microcapsules for the quick release of anticancer drugs in BGC 823 and HeLa tumor cells

2017 ◽  
Vol 5 (48) ◽  
pp. 9477-9481 ◽  
Author(s):  
Yuqing Niu ◽  
Florian J. Stadler ◽  
Tao He ◽  
Xingcai Zhang ◽  
Yingjie Yu ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Tumor Cell ◽  
Real Time ◽  
Tumor Cells ◽  
Anticancer Drugs ◽  
Real Time Monitoring ◽  
Triggered Release ◽  
Quick Release ◽  
Cell Internalization

Smart fluorescent polyurethane microcapsules with high tumor cell internalization, triggered release were developed for precision real-time monitoring cancer therapy.

OPTICAL CHARACTERISTICS OF THE CANINE PROSTATE AT 665 NM SENSITIZED WITH TIN ETIOPURPURIN DICHLORIDE: NEED FOR REAL-TIME MONITORING OF PHOTODYNAMIC THERAPY

2004 ◽  
Vol 172 (2) ◽  
pp. 739-743 ◽  
Author(s):  
JERZY JANKUN ◽  
LOTHAR LILGE ◽  
ALEXANDER DOUPLIK ◽  
RICK W. KECK ◽  
MACIEJ PESTKA ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Real Time ◽  
Optical Characteristics ◽  
Real Time Monitoring

Activatable Ferritin Nanocomplex for Real-Time Monitoring of Caspase-3 Activation during Photodynamic Therapy

2015 ◽  
Vol 7 (41) ◽  
pp. 23248-23256 ◽  
Author(s):  
Jingjing Wang ◽  
Liwen Zhang ◽  
Minglong Chen ◽  
Shi Gao ◽  
Lei Zhu
Keyword(s):  
Photodynamic Therapy ◽  
Real Time ◽  
Caspase 3 ◽  
Real Time Monitoring

Real-Time Monitoring of Singlet Oxygen and Oxygen Partial Pressure During the Deep Photodynamic Therapy In Vitro

2016 ◽  
Vol 44 (9) ◽  
pp. 2737-2745 ◽  
Author(s):  
Weitao Li ◽  
Dong Huang ◽  
Yan Zhang ◽  
Yangyang Liu ◽  
Yueqing Gu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Oxygen Partial Pressure ◽  
Partial Pressure ◽  
Singlet Oxygen ◽  
Real Time ◽  
Real Time Monitoring

A nanoporous photosensitizing hydrogel based on chitosan cross-linked by zinc phthalocyanine: an injectable and pH-stimuli responsive system for effective cancer therapy

RSC Advances ◽  
2016 ◽  
Vol 6 (94) ◽  
pp. 91445-91452 ◽  
Author(s):  
Ali Reza Karimi ◽  
Azam Khodadadi ◽  
Mahnaz Hadizadeh
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Therapeutic Efficacy ◽  
Zinc Phthalocyanine ◽  
Stimuli Responsive ◽  
Zinc Phthalocyanines ◽  
Tumor Selectivity ◽  
Biological Environment ◽  
Low Solubility ◽  
Effective Cancer Therapy

Although zinc phthalocyanines (ZnPcs) have promising applications in photodynamic therapy (PDT), their therapeutic efficacy suffer from their low solubility in the biological environment and their lack of tumor selectivity.

Fully automated, on-site isolation of cfDNA from whole blood for cancer therapy monitoring

Lab on a Chip ◽  
2018 ◽  
Vol 18 (9) ◽  
pp. 1320-1329 ◽  
Author(s):  
Chi-Ju Kim ◽  
Juhee Park ◽  
Vijaya Sunkara ◽  
Tae-Hyeong Kim ◽  
Yongjin Lee ◽  
...  
Keyword(s):  
Targeted Therapy ◽  
Cancer Therapy ◽  
Real Time ◽  
Whole Blood ◽  
Therapy Monitoring ◽  
Real Time Monitoring ◽  
Site Isolation ◽  
Mutation Status ◽  
Fully Integrated

Fully integrated lab-on-a-disc for cfDNA isolation allows real-time monitoring of tumor mutation status during targeted therapy.

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