Ion binding and reactivity at charged aqueous interfaces

1991 ◽  
Vol 24 (12) ◽  
pp. 357-364 ◽  
Author(s):  
Clifford A. Bunton ◽  
Faruk Nome ◽  
Frank H. Quina ◽  
Laurence S. Romsted
Keyword(s):  
Ion Binding ◽  
Aqueous Interfaces

Molecular Recognition and Hydration Energy Mismatch Combine To Inform Ion Binding Selectivity at Aqueous Interfaces

2020 ◽  
Vol 124 (49) ◽  
pp. 10171-10180
Author(s):  
Jennifer F. Neal ◽  
Ankur Saha ◽  
Mia M. Zerkle ◽  
Wei Zhao ◽  
Mickey M. Rogers ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Ion Binding ◽  
Hydration Energy ◽  
Binding Selectivity ◽  
Aqueous Interfaces

Photophysical Characterisation, Metal Ion Binding and Enantiomeric Recognition of Chiral Ligands Containing Phenazine Fluorophore

2004 ◽  
Vol 69 (4) ◽  
pp. 885-896 ◽  
Author(s):  
Luisa Stella Dolci ◽  
Péter Huszthy ◽  
Erika Samu ◽  
Marco Montalti ◽  
Luca Prodi ◽  
...  
Keyword(s):  
Metal Ion ◽  
Photophysical Properties ◽  
Ion Binding ◽  
Metal Ion Binding ◽  
Ammonium Ions ◽  
Enantiomerically Pure ◽  
Binding Process ◽  
High Affinity ◽  
Enantiomeric Recognition ◽  
Chiral Species

Enantiomerically pure dimethyl- and diisobutyl-substituted phenazino-18-crown-6 ligands bind metal and ammonium ions and also primary aralkylammonium perchlorates in acetonitrile with high affinity, causing pronounced changes in their luminescence properties. In addition, they show enantioselectivity towards chiral primary aralkylammonium perchlorates. The possibility to monitor the binding process by photoluminescence spectroscopy can gain ground for the design of very efficient enantioselective chemosensors for chiral species. The observed changes in the photophysical properties are also an important tool for understanding the interactions present in the adduct.

Selective Ion Binding by Protein Probed with the Statistical Mechanical Integral Equation Theory

2007 ◽  
Vol 111 (17) ◽  
pp. 4588-4595 ◽  
Author(s):  
Norio Yoshida ◽  
Saree Phongphanphanee ◽  
Fumio Hirata
Keyword(s):  
Integral Equation ◽  
Integral Equation Theory ◽  
Ion Binding ◽  
Statistical Mechanical

scholarly journals Voltage-dependent modulation of ion binding and translocation in the cardiac Na(+)-Ca2+ exchange system

1991 ◽  
Vol 266 (21) ◽  
pp. 13764-13769
Author(s):  
D. Khananshvili
Keyword(s):  
Ion Binding ◽  
Exchange System ◽  
Voltage Dependent

scholarly journals Thermodynamics of ion binding and occupancy in potassium channels

2021 ◽  
Author(s):  
Zhifeng Jing ◽  
Joshua A. Rackers ◽  
Lawrence Pratt ◽  
Chengwen Liu ◽  
Susan B. Rempe ◽  
...  
Keyword(s):  
Potassium Channels ◽  
Ion Binding ◽  
Cellular Functions ◽  
Ion Conduction

Potassium channels modulate various cellular functions through efficient and selective conduction of K+ ions. The mechanism of ion conduction in potassium channels has recently emerged as a topic of debate....

scholarly journals Manganous ion binding to tubulin.

1980 ◽  
Vol 255 (5) ◽  
pp. 2164-2168
Author(s):  
D.H. Buttlaire ◽  
B.A. Czuba ◽  
T.H. Stevens ◽  
Y.C. Lee ◽  
R.H. Himes
Keyword(s):  
Ion Binding

scholarly journals Snapshots of a Non-Canonical RdRP in Action

Viruses ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1260
Author(s):  
Diego S. Ferrero ◽  
Michela Falqui ◽  
Nuria Verdaguer
Keyword(s):  
Metal Ion ◽  
Rna Viruses ◽  
Ion Binding ◽  
Genome Replication ◽  
Metal Ion Binding ◽  
Insect Virus ◽  
X Ray ◽  
Template Strand ◽  
Nucleotide Incorporation ◽  
Elongation Process

RNA viruses typically encode their own RNA-dependent RNA polymerase (RdRP) to ensure genome replication and transcription. The closed “right hand” architecture of RdRPs encircles seven conserved structural motifs (A to G) that regulate the polymerization activity. The four palm motifs, arranged in the sequential order A to D, are common to all known template dependent polynucleotide polymerases, with motifs A and C containing the catalytic aspartic acid residues. Exceptions to this design have been reported in members of the Permutotetraviridae and Birnaviridae families of positive single stranded (+ss) and double-stranded (ds) RNA viruses, respectively. In these enzymes, motif C is located upstream of motif A, displaying a permuted C–A–B–D connectivity. Here we study the details of the replication elongation process in the non-canonical RdRP of the Thosea asigna virus (TaV), an insect virus from the Permutatetraviridae family. We report the X-ray structures of three replicative complexes of the TaV polymerase obtained with an RNA template-primer in the absence and in the presence of incoming rNTPs. The structures captured different replication events and allowed to define the critical interactions involved in: (i) the positioning of the acceptor base of the template strand, (ii) the positioning of the 3’-OH group of the primer nucleotide during RNA replication and (iii) the recognition and positioning of the incoming nucleotide. Structural comparisons unveiled a closure of the active site on the RNA template-primer binding, before rNTP entry. This conformational rearrangement that also includes the repositioning of the motif A aspartate for the catalytic reaction to take place is maintained on rNTP and metal ion binding and after nucleotide incorporation, before translocation.

Sign in / Sign up

Export Citation Format

Share Document