Ligand binding site interaction in adenosine cyclic 3',5'-monophosphate-dependent protein kinase catalytic subunit: circular dichroic evidence for intramolecular transmission of conformational change

Biochemistry ◽

10.1021/bi00300a026 ◽

1984 ◽

Vol 23 (5) ◽

pp. 968-973 ◽

Author(s):

Jennifer Reed ◽

Volker Kinzel

Keyword(s):

Protein Kinase ◽

Ligand Binding ◽

Binding Site ◽

Conformational Change ◽

Catalytic Subunit ◽

Ligand Binding Site ◽

Dependent Protein Kinase ◽

Dependent Protein ◽

Circular Dichroic

Download Full-text

Circular dichroic evidence for an ordered sequence of ligand/binding site interactions in the catalytic reaction of the cAMP-dependent protein kinase

Biochemistry ◽

10.1021/bi00333a024 ◽

1985 ◽

Vol 24 (12) ◽

pp. 2967-2973 ◽

Author(s):

Jennifer Reed ◽

Volker Kinzel ◽

Bruce E. Kemp ◽

Hueng Chin Cheng ◽

Donal A. Walsh

Keyword(s):

Protein Kinase ◽

Ligand Binding ◽

Binding Site ◽

Catalytic Reaction ◽

Ligand Binding Site ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein ◽

Circular Dichroic

Download Full-text

Adenosine cyclic 3',5'-monophosphate dependent protein kinase: a new fluorescence displacement titration technique for characterizing the nucleotide binding site on the catalytic subunit

Biochemistry ◽

10.1021/bi00295a042 ◽

1983 ◽

Vol 22 (26) ◽

pp. 6310-6317 ◽

Author(s):

Deepak Bhatnagar ◽

Robert Roskoski ◽

Mary S. Rosendahl ◽

Nelson J. Leonard

Keyword(s):

Protein Kinase ◽

Binding Site ◽

Protein Kinase A ◽

Nucleotide Binding ◽

Nucleotide Binding Site ◽

Catalytic Subunit ◽

Dependent Protein Kinase ◽

Dependent Protein ◽

Titration Technique ◽

Download Full-text

Mapping the ATP-Binding Site in the Catalytic Subunit of A denosine-3':5'-monophosphate-Dependent Protein Kinase. Spatial Relationship with the ATP Site of the Undissociated Enzyme

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1978.tb12621.x ◽

1978 ◽

Vol 90 (3) ◽

pp. 427-432 ◽

Author(s):

Jurgen HOPPE ◽

Wolfgang FREIST ◽

Rainer MARUTZKY ◽

Shmuel SHALTIEL

Keyword(s):

Protein Kinase ◽

Binding Site ◽

Spatial Relationship ◽

Catalytic Subunit ◽

Atp Binding ◽

Dependent Protein Kinase ◽

Atp Binding Site ◽

Dependent Protein

Download Full-text

Affinity labeling of the nucleotide binding site of the catalytic subunit of cAMP-dependent protein kinase using p-fluorosulfonyl-[14C]benzoyl 5'-adenosine. Identification of a modified lysine residue.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)86899-0 ◽

1979 ◽

Vol 254 (17) ◽

pp. 8363-8368 ◽

Author(s):

M.J. Zoller ◽

S.S. Taylor

Keyword(s):

Protein Kinase ◽

Binding Site ◽

Nucleotide Binding ◽

Lysine Residue ◽

Nucleotide Binding Site ◽

Catalytic Subunit ◽

Affinity Labeling ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

Download Full-text

MgATP-induced conformational change of the catalytic subunit of cAMP-dependent protein kinase

Biophysical Chemistry ◽

10.1016/j.bpc.2004.08.008 ◽

2005 ◽

Vol 113 (2) ◽

pp. 193-199 ◽

Author(s):

Shumei Yang ◽

Kestrel M. Rogers ◽

David A. Johnson

Keyword(s):

Protein Kinase ◽

Conformational Change ◽

Catalytic Subunit ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

Download Full-text

Fluorescence energy transfer between cysteine 199 and cysteine 343: evidence for magnesium ATP-dependent conformational change in the catalytic subunit of cAMP-dependent protein kinase

Biochemistry ◽

10.1021/bi00434a068 ◽

1989 ◽

Vol 28 (8) ◽

pp. 3606-3613 ◽

Author(s):

Eric A. First ◽

David A. Johnson ◽

Susan S. Taylor

Keyword(s):

Energy Transfer ◽

Protein Kinase ◽

Conformational Change ◽

Catalytic Subunit ◽

Fluorescence Energy Transfer ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein ◽

Fluorescence Energy

Download Full-text

Calculating pKa values in the cAMP-dependent protein kinase: The effect of conformational change and ligand binding

Protein Science ◽

10.1002/pro.530 ◽

2010 ◽

Vol 19 (12) ◽

pp. 2485-2497 ◽

Author(s):

Una Bjarnadottir ◽

Jens Erik Nielsen

Keyword(s):

Protein Kinase ◽

Ligand Binding ◽

Conformational Change ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

Download Full-text

Rapid and reversible translocation of the catalytic subunit of cAMP-dependent protein kinase type II from the Golgi complex to the nucleus.

The EMBO Journal ◽

10.1002/j.1460-2075.1985.tb04006.x ◽

1985 ◽

Vol 4 (11) ◽

pp. 2801-2806 ◽

Author(s):

E.A. Nigg ◽

H. Hilz ◽

H.M. Eppenberger ◽

F. Dutly

Keyword(s):

Protein Kinase ◽

Golgi Complex ◽

Catalytic Subunit ◽

Type Ii ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

Download Full-text

Glutamic acid 203 of the cAMP-dependent protein kinase catalytic subunit participates in the inhibition by two isoforms of the protein kinase inhibitor.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)42170-3 ◽

1994 ◽

Vol 269 (3) ◽

pp. 2316-2323

Author(s):

E.J. Baude ◽

S.S. Dignam ◽

S.R. Olsen ◽

E.M. Reimann ◽

M.D. Uhler

Keyword(s):

Protein Kinase ◽

Glutamic Acid ◽

Kinase Inhibitor ◽

Protein Kinase Inhibitor ◽

Catalytic Subunit ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

Download Full-text

Effect of the thermostable protein kinase inhibitor on intracellular localization of the catalytic subunit of cAMP-dependent protein kinase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)41857-1 ◽

1992 ◽

Vol 267 (24) ◽

pp. 16824-16828 ◽

Author(s):

D.A. Fantozzi ◽

S.S. Taylor ◽

P.W. Howard ◽

R.A. Maurer ◽

J.R. Feramisco ◽

...

Keyword(s):

Protein Kinase ◽

Kinase Inhibitor ◽

Intracellular Localization ◽

Protein Kinase Inhibitor ◽

Catalytic Subunit ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein ◽

Thermostable Protein

Download Full-text